Connect with us

Health

Study Links Specific Genes to Cannabis Use and Addiction Risk

Published

on

New research has found that a person’s genetic makeup may play a key role in whether they try cannabis, how frequently they use it, and their likelihood of developing an addiction.

The study, published in the journal Molecular Psychiatry, was conducted by researchers at the University of California, San Diego, in collaboration with DNA testing company 23andMe. It identified several genes that appear to influence cannabis use and its potential link to mental health, cognitive function, and physical health conditions.

“Cannabis is widely used, but its long-term effects on health remain poorly characterised,” said Dr. Sandra Sanchez-Roige, associate professor of psychiatry at UC San Diego and the study’s lead author. She noted that about 30% of people who try cannabis eventually develop cannabis use disorder. “Understanding the genetics of early-stage behaviours may help clarify who is at greater risk, opening the door to prevention and intervention strategies,” she added.

The research analysed data from more than 130,000 participants who shared information about their cannabis use and provided DNA samples. Using genome-wide association studies (GWAS), the team identified two key genes influencing cannabis-related behaviours.

The first, Cell Adhesion Molecule 2 (CADM2), helps brain cells communicate and has previously been linked to impulsivity, obesity, and cancer risk. The second, Metabotropic Glutamate Receptor 3 (GRM3), plays a role in brain plasticity and is associated with psychiatric disorders such as schizophrenia and bipolar disorder.

Beyond these, the study revealed 40 additional genes connected to lifetime cannabis use and four linked to usage frequency, 29 of which had not been previously identified in cannabis-related research.

See also  New Research Suggests Daily Orange Juice Consumption May Influence Thousands of Genes Linked to Heart Health

When the findings were compared with major U.S. health databases, the researchers discovered more than 100 related traits and conditions, including attention-deficit/hyperactivity disorder (ADHD), anxiety, depression, and risk-taking behaviours. Physical health links included diabetes, chronic pain, autoimmune disorders, and higher susceptibility to infectious diseases such as HIV and hepatitis.

Dr. Hayley Thorpe, a postdoctoral researcher at Western University and a co-author of the study, said that while genetics can increase a person’s vulnerability, environmental factors and personal choices remain critical. “By studying these intermediate traits, we can begin to map how genetic risk unfolds before cannabis use disorder develops,” she explained.

The findings come as global cannabis use continues to rise. According to the World Health Organization, around 147 million people—2.5% of the world’s population—use cannabis. In Europe alone, about 8.4% of adults aged 15 to 64 reported using the drug in the past year, with 1.5% identified as daily or near-daily users.

Researchers hope the new insights into genetic pathways could eventually lead to targeted prevention strategies and improved treatment for cannabis-related disorders.

Health

New Review Finds Plant-Based Diets Safe for Children When Properly Supplemented

Published

on

A major scientific review has concluded that children can safely follow vegetarian or vegan diets, provided they receive the right supplements or consume foods fortified with essential nutrients. The findings, published in Critical Reviews in Food Science and Nutrition, assessed how plant-based eating patterns affect growth, health, and nutrient intake among young people.

Researchers examined data from nearly 49,000 children and teenagers across 18 countries, comparing those who followed vegetarian, vegan, and omnivorous diets. The study’s lead author, Monica Dinu of the University of Florence, said the results show that plant-based diets can support healthy development when they are carefully planned. She stressed that key nutrients must be monitored to avoid deficiencies.

The review found that vegetarian children typically consumed more fibre, iron, folate, vitamin C, and magnesium than their meat-eating peers. However, their intake of energy, protein, fat, vitamin B12, vitamin D, and zinc was lower. Similar patterns were observed among vegan children, whose calcium intake was notably low. According to the researchers, vitamin B12 was consistently inadequate without fortified foods or supplements.

Study co-author Jeannette Beasley of New York University noted that children on vegetarian and vegan diets may require supplementation for nutrients such as vitamin B12, calcium, iodine, and zinc. These gaps were most evident among vegans, who avoid all animal products, including dairy and eggs.

Despite these shortcomings, the review identified several health advantages linked to plant-based diets. Both vegetarian and vegan children showed signs of stronger cardiovascular health compared with omnivores. The study reported lower cholesterol levels, including reduced low-density lipoprotein (LDL) cholesterol, which is associated with a higher risk of heart disease. Vegetarian children were generally slightly shorter and leaner, with lower body mass index and fat mass, though these differences remained within healthy ranges.

See also  Tanzania Reports Deadly Marburg Virus Outbreak, Eight Fatalities Confirmed

The authors cautioned that interpreting the results has limitations. It remains difficult to determine whether the diets themselves caused the observed health outcomes. Families adopting plant-based eating patterns may also differ in lifestyle or socioeconomic factors that influence children’s health.

Given the increasing number of households adopting plant-based diets for ethical, environmental, or health reasons, researchers urged parents to seek guidance from paediatricians or dieticians when planning meals for children. They also called for more official recommendations to help families ensure adequate nutrient intake during key stages of growth.

Dinu said the team hopes the findings will help families better understand the potential benefits and risks associated with plant-based diets, enabling them to make informed decisions that support children’s long-term wellbeing.

Continue Reading

Health

Sperm Donor with Cancer-Causing Mutation Fathers Nearly 200 Children Across Europe

Published

on

A sperm donor carrying a rare cancer-causing genetic mutation has fathered nearly 200 children across Europe, according to an investigation led by the European Broadcasting Union, involving 14 public service broadcasters. The man, who appeared healthy and passed standard screening, donated sperm for approximately 17 years while he was a student.

The mutation, found in the TP53 gene, increases the risk of cells becoming cancerous. Children who inherit the mutation develop Li Fraumeni syndrome, a disorder associated with up to a 90 percent lifetime risk of cancer. Some donor-conceived children have already died, and many more are expected to develop cancer in the future.

Doctors first identified the risk this year after discovering 23 children carrying the mutation among 67 known cases, 10 of whom had already been diagnosed with cancer. Investigators reported that the donor’s sperm was used to conceive at least 197 children in 14 countries, though the actual number may be higher. Children have been born in Denmark, Belgium, Spain, Greece, and Germany, with additional recipients in Ireland, Poland, Albania, Kosovo, and Sweden. A small number of women from the United Kingdom were also treated at clinics in Denmark, according to Peter Thompson, chief executive of the UK’s Human Fertilisation and Embryology Authority.

Denmark’s European Sperm Bank, which supplied the samples, admitted the sperm was overused and expressed “deepest sympathy” to affected families. The bank said the mutation could not have been detected through routine screening and immediately blocked the donor once the problem was discovered.

Experts have described the case as both a regulatory failure and an extraordinary coincidence. Jackson Kirkman-Brown, a professor at the University of Birmingham, noted that detecting new mutations in sperm is difficult and that the core issue lies in insufficient monitoring of how often a single donor’s sperm is used. Clare Turnbull from the UK Institute of Cancer Research said the situation reflects a highly unusual combination: a donor carrying a rare mutation and that same sperm being used to create a large number of children. She added that the mutation likely arose in the donor’s testes and spread among sperm cells, a phenomenon known as selfish spermatogonial selection.

See also  Experts Warn Poorly Designed Tech Could Add to Doctors’ Workload, Not Ease It

The investigation has also highlighted differences in European regulations on sperm donation. Family and child limits vary widely: in Cyprus, a donor may contribute to only one child, while France, Greece, Italy, and Poland allow up to 10. Denmark limits donations to 12 families, and Sweden and Norway to six families. Some countries maintain anonymous donations, though disclosure may occur in cases of severe health conditions.

Euronews Health has contacted the European Sperm Bank for comment but has not yet received a response. The case has renewed calls from experts for tighter international oversight of sperm donation to prevent similar incidents in the future.

Continue Reading

Health

AI Note-Taking Tool Gives European Clinicians More Time With Patients, Study Finds

Published

on

A new analysis from Swedish firm Tandem Health suggests that automated note-taking technology is reducing paperwork for clinicians across Europe and allowing them to spend more meaningful time with patients.

The company reviewed more than 375,000 medical notes produced with its AI scribe, a tool now used by nearly 1,300 clinicians in 11 European countries, including the UK, France and Spain. The findings indicate that the technology shortened the average time spent writing notes from 6.69 minutes to 4.71 minutes — a 29% drop.

Tandem Health also surveyed 177 clinicians, ranging from GPs and surgeons to psychologists and nurses. Many said the reduction in administrative work allowed them to feel more attentive during consultations, while some reported a noticeable decrease in stress linked to routine documentation.

Health workforce fatigue remains a growing concern in Europe. An international survey published earlier this year found that administrative overload is a major factor behind burnout among primary care doctors. In the UK, 28% of GPs who reported burnout said excessive paperwork was the main cause. In Switzerland, the proportion rose to 65%.

Tandem Health CEO Lukas Saari said the results highlight how digital tools could support overstretched services. “For European healthcare systems facing acute workforce shortages and rising costs, that capacity gain could make a real difference at scale, addressing wait times, clinician burnout and care access,” he said.

The company stressed that much of the existing research on AI scribes comes from the United States, where healthcare structures differ significantly from those in Europe. Tandem Health’s scribe is classified as a medical device under EU rules, and the firm says more regional evidence is necessary as adoption grows.

See also  WHO Urges Continued Funding for PEPFAR as US Freezes Foreign Aid

Dr Artin Entezarjou, head of medical operations at Tandem Health, said the data offers insight for policymakers and health leaders examining new ways to address persistent staffing pressures. He noted that European systems must understand how such tools function in their own clinical environments to shape appropriate guidance and investment decisions.

Supporters of the technology argue that even modest efficiency gains could help reduce appointment backlogs and ease strain on health workers. Many clinicians in the survey said the extra time and reduced cognitive load improved the quality of their patient interactions, which they viewed as a central benefit of the scribe.

The findings arrive as hospitals and primary care networks across Europe continue to test digital tools that could take on repetitive administrative duties. Tandem Health says demand for its scribe has risen sharply over the past year as more clinicians explore ways to streamline paperwork without compromising record accuracy.

The company plans to expand data collection to assess long-term effects on patient flow, clinical workload and staff retention.

Continue Reading

Trending