Health
WHO Warns Alcohol a Leading Cause of Cancer in Europe
Alcohol consumption remains one of the major causes of cancer in Europe, according to a new report from the World Health Organization’s International Agency for Research on Cancer (IARC), which has urged governments to strengthen policies aimed at reducing drinking rates.
The IARC study found that alcohol was responsible for more than 111,000 new cancer cases across the European Union in 2020 — the highest rate globally. Worldwide, the number reached an estimated 741,000, with men accounting for nearly 70 per cent of cases.
The WHO warned that the impact of alcohol-related cancers extends far beyond public health. In 2018, premature deaths from such diseases cost European economies €4.58 billion. “The WHO European Region, and especially countries of the EU, are paying too high a price for alcohol in preventable cancers and broken families, as well as costing billions to taxpayers,” said Dr. Gundo Weiler, who leads prevention and health promotion efforts at WHO Europe. “Some call alcohol a ‘cultural heritage’, but disease, death, and disability should not be normalised as part of European culture.”
How Alcohol Contributes to Cancer
Alcohol was first classified as a carcinogen in 1988, and the IARC report confirms it increases the risk of at least seven types of cancer — including cancers of the mouth, throat, oesophagus, liver, colon, rectum, and breast.
Researchers say alcohol causes cancer through several biological mechanisms, such as hormonal imbalances, DNA damage caused by oxidative stress, and exposure to acetaldehyde — a toxic compound produced when the body breaks down ethanol.
Even moderate drinking poses a risk. While most alcohol-related cancers are linked to “risky” (two to six drinks daily) and “heavy” (more than six drinks daily) consumption, the report found that moderate intake — fewer than two drinks per day — contributed to over 100,000 new cancer cases globally in 2020.
Policy and Prevention
For the first time, the IARC evaluated the benefits of reducing alcohol consumption as a means of cancer prevention. “This analysis establishes with no further doubt that population-wide alcohol policies reduce drinking, and that reduced drinking lowers cancer risk,” said Dr. Elisabete Weiderpass, Director of IARC.
The agency called for stronger public health measures, including higher alcohol taxes, minimum pricing, raising the legal drinking age, restricting retail hours, limiting marketing, and government control over alcohol sales.
A 2021 study cited by IARC found that doubling alcohol excise taxes could have prevented six per cent of new alcohol-related cancers and deaths in 2019 in Europe and Central Asia.
Dr. Béatrice Lauby-Secretan, deputy head of IARC’s evidence synthesis and classification branch, stressed the importance of awareness. “No level of drinking is safe,” she said. “Everyone has a role to play in changing the current norms surrounding alcohol consumption.”
Health
Medieval Manuscripts Reveal Thousands-Year History of Deadly Sheep Virus
DNA recovered from medieval manuscripts has given scientists new clues about the long history of sheep pox, a highly contagious disease that has threatened livestock for thousands of years.
An international team led by researchers at University College Dublin discovered traces of sheep pox virus in parchment used for some of Europe’s historic manuscripts. The findings suggest that animal diseases may have left genetic records in old documents, providing scientists with another way to study how pathogens developed over time.
During the Middle Ages, parchment was commonly made from the treated skin of sheep, goats and cattle. Researchers extracted DNA from the animal skins used to produce centuries-old manuscripts and identified genetic material linked to the sheep pox virus.
The study involved geneticists, historians, virologists, protein chemists and conservation specialists. Louis L’Hôte, the study’s lead author, said the research showed that parchment could preserve DNA from animal pathogens and provide valuable evidence about infectious diseases in the past.
Among the manuscripts examined was the approximately 1,000-year-old York Gospels, considered one of the finest surviving illuminated manuscripts from the late Anglo-Saxon period. Researchers also examined the Corpus Glossary at Corpus Christi College in Cambridge, an early English dictionary, along with other medieval texts from Britain and continental Europe.
In some manuscripts, several pages contained sheep pox virus DNA. Researchers said this could indicate that animals infected with the disease were used to produce the parchment.
The team compared the genetic material recovered from the manuscripts with older DNA samples obtained from Bronze Age sheep teeth. Their analysis indicated that sheep pox has affected livestock for more than 3,700 years.
Sheep pox spreads quickly among animals and can infect a large proportion of a flock. The disease causes fever and skin lesions and can result in death. Outbreaks can also cause major financial losses through reduced milk production, damage to wool and hides, and restrictions on livestock trade.
There is no evidence that sheep pox infects humans.
The research, published in Science Advances, also provided insight into how the virus changed over time. Scientists found that the sheep pox virus genome remained relatively stable during the past several thousand years.
L’Hôte said the finding contrasts with the evolutionary history of some other pathogens, including smallpox. The stability of the sheep pox genome may indicate that important genetic changes occurred much earlier in the virus’s history and helped it adapt to sheep.
Researchers said the work could encourage scientists to examine other archives and libraries for genetic traces of historic animal diseases. Ancient DNA preserved in manuscripts could offer a new source of information about outbreaks that affected livestock and societies long before modern disease surveillance existed.
Health
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