Health
Europe Struggles to Meet Tuberculosis Targets Amid Rising Drug Resistance
Tuberculosis remains a public health issue in Europe as the region falls behind elimination targets, according to a new report by the World Health Organization (WHO) and the European Centre for Disease Prevention and Control (ECDC). The report warns that one in five cases goes undiagnosed, while drug resistance continues to exceed global averages.
Although the overall number of TB cases has declined, progress toward elimination remains insufficient. Tuberculosis, an infectious disease spread when an individual with pulmonary TB expels bacteria through coughing, is the leading cause of death from a single infectious agent worldwide. Common symptoms include a persistent cough lasting more than two weeks, fever, night sweats, and weight loss.
Across the WHO European Region, which covers 53 countries in Europe and Central Asia, TB incidence has fallen by 39 percent since 2015, and deaths have dropped by 49 percent. These figures fall short of the WHO’s End TB Strategy 2025 milestones of 50 percent reduction in cases and 75 percent reduction in deaths.
Within the European Union, cases have decreased by 33 percent and deaths by 17 percent, insufficient to meet the 2030 targets. Health authorities note this gap has led to thousands of preventable infections and fatalities. In 2024, more than 160,000 newly diagnosed TB cases were reported, while the estimated actual number of cases was 204,000, meaning only 79 percent were officially notified.
Hans Kluge, WHO Regional Director for Europe, said undiagnosed cases represent missed opportunities to treat patients earlier and curb transmission. “By investing in rapid diagnosis, shorter all-oral treatment regimens and stronger follow-up, countries can reach more people earlier, improve outcomes and put us back on track toward our targets,” he said. Delayed diagnosis increases treatment difficulty and heightens the risk of spreading the disease.
Drug-resistant tuberculosis remains a major challenge. Multi-drug resistant TB among new and previously treated cases stands at 23 percent and 51 percent, respectively, far above the global averages of 3.2 percent and 16 percent. Standard treatment for non-resistant TB typically lasts six months with success rates above 85 percent, but resistant variants require longer, more complex regimens with lower success rates.
Most European countries now report low TB incidence, with notification rates below 10 per 100,000. The disease mainly affects vulnerable populations, including migrants, prison inmates, and people with HIV co-infections. Ralf Otto-Knapp of the German Central Committee against Tuberculosis warned that lower overall case numbers in Western Europe have led to decreased attention, making it harder to combat multidrug-resistant TB. “We must strengthen treatment and prevention services, ensure easy access to new medicines and foster cross-border cooperation,” he said.
The report underscores that without urgent action on diagnosis, treatment, and drug resistance, Europe risks falling further behind its TB elimination goals, putting vulnerable communities at heightened risk.
Health
Medieval Manuscripts Reveal Thousands-Year History of Deadly Sheep Virus
DNA recovered from medieval manuscripts has given scientists new clues about the long history of sheep pox, a highly contagious disease that has threatened livestock for thousands of years.
An international team led by researchers at University College Dublin discovered traces of sheep pox virus in parchment used for some of Europe’s historic manuscripts. The findings suggest that animal diseases may have left genetic records in old documents, providing scientists with another way to study how pathogens developed over time.
During the Middle Ages, parchment was commonly made from the treated skin of sheep, goats and cattle. Researchers extracted DNA from the animal skins used to produce centuries-old manuscripts and identified genetic material linked to the sheep pox virus.
The study involved geneticists, historians, virologists, protein chemists and conservation specialists. Louis L’Hôte, the study’s lead author, said the research showed that parchment could preserve DNA from animal pathogens and provide valuable evidence about infectious diseases in the past.
Among the manuscripts examined was the approximately 1,000-year-old York Gospels, considered one of the finest surviving illuminated manuscripts from the late Anglo-Saxon period. Researchers also examined the Corpus Glossary at Corpus Christi College in Cambridge, an early English dictionary, along with other medieval texts from Britain and continental Europe.
In some manuscripts, several pages contained sheep pox virus DNA. Researchers said this could indicate that animals infected with the disease were used to produce the parchment.
The team compared the genetic material recovered from the manuscripts with older DNA samples obtained from Bronze Age sheep teeth. Their analysis indicated that sheep pox has affected livestock for more than 3,700 years.
Sheep pox spreads quickly among animals and can infect a large proportion of a flock. The disease causes fever and skin lesions and can result in death. Outbreaks can also cause major financial losses through reduced milk production, damage to wool and hides, and restrictions on livestock trade.
There is no evidence that sheep pox infects humans.
The research, published in Science Advances, also provided insight into how the virus changed over time. Scientists found that the sheep pox virus genome remained relatively stable during the past several thousand years.
L’Hôte said the finding contrasts with the evolutionary history of some other pathogens, including smallpox. The stability of the sheep pox genome may indicate that important genetic changes occurred much earlier in the virus’s history and helped it adapt to sheep.
Researchers said the work could encourage scientists to examine other archives and libraries for genetic traces of historic animal diseases. Ancient DNA preserved in manuscripts could offer a new source of information about outbreaks that affected livestock and societies long before modern disease surveillance existed.
Health
North African Dust Set to Worsen Air Quality Across Portugal
Health
New Zealand Approves MDMA Treatment for Severe PTSD Under Strict Medical Controls
-
Entertainment2 years agoMeta Acquires Tilda Swinton VR Doc ‘Impulse: Playing With Reality’
-
Sports2 years agoChina’s Historic Olympic Victory Sparks National Pride Amid Controversy
-
Business2 years agoSaudi Arabia’s Model for Sustainable Aviation Practices
-
Business2 years agoRecent Developments in Small Business Taxes
-
Home Improvement2 years agoEffective Drain Cleaning: A Key to a Healthy Plumbing System
-
Politics2 years agoWho was Ebrahim Raisi and his status in Iranian Politics?
-
Sports2 years agoKeely Hodgkinson Wins Britain’s First Athletics Gold at Paris Olympics in 800m
-
Business2 years agoCarrectly: Revolutionizing Car Care in Chicago
