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Psychedelic Therapies Gain Attention as Mental Health Crisis Deepens

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As mental health disorders continue to rise worldwide, researchers are increasingly turning to psychedelic-assisted therapy as a possible new treatment for conditions such as depression and post-traumatic stress disorder, particularly in patients who do not respond to conventional care.

Scientists and mental health experts say the growing interest reflects frustration with the limited progress in psychiatric medicine over recent decades. According to the World Health Organization, more than one billion people globally are living with mental health conditions, placing pressure on healthcare systems to find more effective therapies.

Psychedelic-assisted treatment typically combines controlled doses of psychoactive substances with professional psychological support in carefully monitored settings. Patients are guided through the experience by trained clinicians, often in quiet rooms designed to reduce stress and encourage emotional openness.

Among the substances under study, psilocybin — the active compound found in so-called magic mushrooms — has emerged as one of the most promising. Researchers say it may help patients break free from rigid patterns of thinking commonly linked to severe depression.

Dr Liliana Galindo, assistant professor in psychiatry at the University of Cambridge, said psychedelic research offers hope for patients who have exhausted existing treatment options.

“Unfortunately, in psychiatry, we haven’t really had many new treatments for decades,” she said. “Psychedelics are opening the possibility for treatments aimed at people who do not respond to standard therapies.”

A synthetic form of psilocybin known as COMP360 has already completed phase three clinical trials for treatment-resistant depression. Developers are expected to seek approval from the US Food and Drug Administration, raising the possibility that psilocybin could become the first approved psychedelic-based mental health treatment.

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Researchers believe psychedelics work differently from traditional antidepressants. Rather than only easing symptoms, they may temporarily alter brain activity in ways that allow patients to rethink traumatic memories, emotional responses and long-standing negative thought patterns.

Studies from institutions including Imperial College London suggest even a single controlled dose of psilocybin may produce measurable changes in brain function.

Other compounds, including MDMA, are also being studied for their potential to treat PTSD by helping patients revisit traumatic memories in a less fearful state.

Despite the growing scientific interest, significant obstacles remain. Psychedelics are still illegal in many countries and are often associated with recreational drug use. In the United Kingdom, substances such as psilocybin remain classified as Class A drugs, creating strict licensing requirements for researchers.

Experts also warn that psychedelic treatments should never be used without medical supervision. Controlled environments, trained therapists and careful patient screening are considered essential to reduce risks and manage possible side effects.

Researchers say more studies are still needed to determine who benefits most from psychedelic-assisted therapy. However, supporters believe the field could eventually transform mental healthcare if treatments prove both safe and effective.

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AI Models Show Ability to Mimic Human Emotions, Offering New Pathways for Mental Health Research

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Artificial intelligence systems may be able to imitate human emotional responses in controlled settings, potentially opening new directions for mental health research, according to a recent study from Dresden University of Technology in Germany.

The findings come at a time when mental health conditions are rising globally, with projections suggesting that up to 1.2 billion people could be affected by 2050. Researchers say this growing challenge highlights the need for improved understanding of psychological disorders and more effective treatment approaches, particularly in talk-based therapies that are difficult to model through traditional methods.

Unlike drug development, which can rely on biological testing, psychotherapy research faces limitations because neither animal models nor human trials can fully capture the complexity of emotional and cognitive processes. Scientists involved in the study argue that large language models (LLMs) may help bridge part of this gap.

“Our results show that large language models can reproduce patterns of human affective and cognitive processes under controlled conditions,” said Dr Magdalena Wekenborg, who leads the PsychoDigital Research group at TU Dresden. She added that such systems could support efforts to better understand underlying psychological mechanisms and help explore new forms of psychotherapy research.

The study examined whether LLMs could replicate emotional states such as fear, anxiety, anger, sadness, disgust, worry, and stress when prompted. Researchers then tested whether those induced states could be altered using different emotional regulation techniques, and whether emotional prompting would lead the models to make errors similar to those seen in humans experiencing the same feelings.

Findings showed that while artificial intelligence systems do not experience emotions in a human sense, they are capable of reproducing certain patterns of emotional reasoning through language processing. This allows researchers to observe behaviour that resembles human cognitive responses under structured conditions.

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The team also noted that such models offer a level of experimental control that is not possible in human or animal studies. According to researcher Jakob N. Kather, experiments can be repeated under identical conditions and adjusted systematically, allowing for more precise comparisons.

He said this could enable new data-driven approaches in psychological and biomedical research, particularly in areas where ethical or practical constraints have limited traditional experimentation.

While the study does not suggest that artificial intelligence understands emotion as humans do, it highlights how language models may serve as useful tools for exploring aspects of mental health and human cognition in ways that were previously out of reach.

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AI Saves Clinicians Weeks of Work but Health Systems Struggle to Keep Up, Philips Report Finds

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Healthcare professionals are gaining significant time savings through artificial intelligence tools, but health systems are struggling to adapt quickly enough to the rapid pace of change, according to a new global report.

The findings come from the Future Health Index 2026 report published by health technology company Philips, which examined how AI is being used across hospitals and clinics and its impact on clinical workflows.

The study surveyed more than 2,000 clinicians and over 20,000 patients across 10 countries, including the United Kingdom, United States, Germany, France, China and India. It found that AI adoption among healthcare workers has increased significantly over the past year, with growing confidence in its ability to improve patient care.

More than 80% of healthcare professionals said they are optimistic about AI’s impact on patient outcomes, while around 70% believe the benefits already outweigh the risks. Many clinicians reported that AI is already making a measurable difference in their daily work.

According to the report, 46% of clinicians said they save at least 132 hours per year through AI-enabled tools, equivalent to more than three working weeks. Nurses were among those reporting the greatest time savings, particularly from reduced administrative workloads.

Shez Partovi, Chief Innovation Officer at Philips, said clinicians are increasingly able to redirect that time toward patient care, collaboration and reflection on complex medical cases. He noted improvements in work-life balance, reduced stress and greater efficiency across clinical teams.

Around 71% of respondents said AI has improved workflow efficiency, while half said it has allowed them to see more patients. Approximately the same proportion reported better work-life balance and lower stress levels.

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Common uses of AI include transcribing medical notes, scheduling appointments and assisting with diagnostic tasks such as reviewing X-rays. Some clinicians also described using AI systems as support tools for clinical discussions and decision-making, including identifying potential drug interactions.

The report also found that 39% of clinicians had seen AI help identify or prevent potential medical errors multiple times in recent months, while more than 65% said it had improved their confidence in clinical decisions.

Despite these gains, the report highlights growing pressure on health systems to keep pace with demand for AI tools. Nearly two-thirds of clinicians said they turn to personal AI applications when workplace systems are insufficient, raising concerns about governance and data security.

Seven in 10 respondents said training for AI tools is limited or inconsistent, suggesting organisations are struggling to implement structured adoption programmes. Partovi said this reflects a gap between rapid technological advancement and slower institutional rollout.

He added that hospitals face complex challenges including privacy, safety, regulatory oversight and role-specific training, all of which must be addressed to ensure safe deployment.

Looking ahead, 96% of healthcare professionals expect AI to change their roles, with more than half anticipating major shifts in how they work. However, concerns remain, with 44% worried about losing clinical skills due to over-reliance on AI and 37% saying changes are happening faster than they are comfortable with.

Even so, most clinicians emphasised that human oversight remains essential. Around 86% said AI outputs must always be reviewed by healthcare professionals, while more than 80% said technology will not replace the patient-clinician relationship.

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WHO Warns Unsafe Food Causes Over 1.5 Million Deaths a Year, Children Most at Risk

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Unsafe food continues to pose a major global health threat, causing hundreds of millions of illnesses and more than 1.5 million deaths each year, according to a new warning from the World Health Organization.

The WHO estimates that over 860 million people fall ill annually due to contaminated or improperly handled food, with children under the age of five bearing a disproportionate share of the burden. The findings were released ahead of World Food Safety Day on 7 June and highlight the widespread impact of foodborne disease across all regions.

World Health Organization Director-General Dr Tedros Adhanom Ghebreyesus said food safety is a daily concern affecting families worldwide. He noted that while unsafe food has long been recognised as a public health issue, global data now provides a clearer picture of its scale and economic cost.

The report estimates that foodborne illnesses led to around $310 billion in lost productivity in 2021 alone. Health officials say many of these cases could be prevented through improved sanitation, safer food handling practices such as pasteurisation, and better access to healthcare services for vulnerable populations.

Climate change is also emerging as a growing risk factor. Rising temperatures, extreme weather events and changing rainfall patterns are expected to increase the spread of foodborne pathogens and create new food safety challenges in the years ahead.

Children remain the most affected group. Those under five are three times more likely to suffer foodborne illness compared with older children and adults. In 2021, they accounted for 29 percent of the global health burden linked to unsafe food and 143,000 deaths.

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Although they represent a small share of the global population, young children experience nearly one-third of all foodborne disease cases, particularly diarrhoeal infections that can quickly become life-threatening. The WHO also warned that exposure to chemical contaminants in food can disrupt brain development and cause long-term neurological harm in children.

The burden of unsafe food is also unevenly distributed. Low-income countries in Africa and South-East Asia account for nearly three-quarters of global foodborne illnesses and about 60 percent of deaths, reflecting deep inequalities in food systems, infrastructure and healthcare access.

Foodborne diseases are caused by bacteria, viruses, parasites or chemical substances entering the body through contaminated food. In Europe, common examples include Campylobacter infections linked to undercooked poultry, Salmonella often associated with eggs and raw meat, STEC infections from undercooked foods and unpasteurised products, and Listeriosis, a rare but severe infection with high hospitalisation rates.

Health experts say that strengthening food safety systems and improving global cooperation will be essential to reducing preventable illness and death linked to contaminated food.

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