Health
Study Links Fathers’ Childhood Exposure to Secondhand Smoke With Poor Lung Health in Their Children
Children whose fathers were exposed to secondhand smoke during childhood face a significantly higher risk of developing poor lung health as adults, according to new Australian research published in the journal Thorax.
The study is among the first to suggest that the damaging effects of tobacco smoke may extend beyond those directly exposed, potentially affecting future generations. Scientists say the findings highlight the intergenerational impact of smoking and the importance of protecting children from passive smoke.
“These findings suggest that smoking may adversely affect lung function not only in smokers but also in their children and grandchildren,” the researchers wrote.
The study tracked 890 fathers and their children, who were born in the early 1960s, over more than five decades. Researchers examined whether the fathers had been regularly exposed to secondhand smoke before puberty — defined as having at least one parent who smoked six or more days a week — and then assessed the lung health of their children at age 53.
Results showed that children of fathers exposed to secondhand smoke during childhood were 56 percent more likely to suffer from poor lung function, measured by forced expiratory volume in one second (FEV1), a key marker of respiratory health. They were also more likely to show signs of rapid decline in lung function, even if they had not yet developed chronic obstructive pulmonary disease (COPD), a leading global cause of death.
“Impaired lung function may begin long before respiratory illnesses become clinically apparent,” said Professor Shyamali Dharmage, of the University of Melbourne’s Allergy and Lung Health Unit, who co-authored the study.
The link remained strong even after accounting for other potential factors, including socioeconomic background and family history of asthma. The association was particularly pronounced among children who themselves were also exposed to secondhand smoke while growing up.
The study found that 69 percent of fathers and 57 percent of their children had been exposed to secondhand smoke in childhood. Nearly half of the children also reported smoking at some point in their lives. However, researchers said the children’s own exposure explained only about 10 percent of the connection between poor lung health and their fathers’ early exposure, suggesting a deeper intergenerational effect.
Scientists believe the mechanism may be biological. Boys exposed to harmful chemicals in cigarette smoke before puberty may undergo changes in the genetic expression of sperm cells, which could then affect the respiratory health of their offspring.
Although the study was observational and cannot definitively prove causation, its authors stressed the importance of preventing children’s exposure to smoke.
“Protecting children from passive smoke could benefit not only their own respiratory health but also that of their offspring,” Dharmage said.
The researchers urged fathers to break the cycle by avoiding smoking around their children, warning that the consequences of exposure may ripple across generations.
Health
Study Finds AI Systems Can Repeat Fake Medical Claims When Framed Credibly
“Large language models accept fake medical claims if presented as realistic in medical notes and social media discussions, a study has found.”
As more people turn to the internet to research symptoms, compare treatments and share personal health experiences, artificial intelligence tools are increasingly being used to answer medical questions. A new study warns that many of these systems remain vulnerable to medical misinformation, particularly when false claims are presented in authoritative or realistic language.
The findings, published in The Lancet Digital Health, show that leading artificial intelligence systems can mistakenly repeat incorrect medical information when it appears in formats that resemble professional healthcare documents or trusted online discussions. Researchers analysed how large language models respond when faced with false medical statements written in a credible tone.
The study examined responses from 20 widely used language models, including systems developed by OpenAI, Meta, Google, Microsoft, Alibaba and Mistral AI, as well as several models specifically fine-tuned for medical use. In total, researchers assessed more than one million prompts designed to test whether AI would accept or reject fabricated health information.
Fake statements were inserted into real hospital discharge notes, drawn from common health myths shared on Reddit, or embedded in simulated clinical scenarios written to resemble authentic healthcare guidance. Across all models tested, incorrect information was accepted around 32 percent of the time. Performance varied significantly, with smaller or less advanced models accepting false claims in more than 60 percent of cases, while more advanced systems, including ChatGPT-4o, did so in roughly 10 percent of responses.
The researchers also found that medical fine-tuned models performed worse than general-purpose systems, raising concerns about tools designed specifically for healthcare use.
“Our findings show that current AI systems can treat confident medical language as true by default, even when it’s clearly wrong,” said Eyal Klang of the Icahn School of Medicine at Mount Sinai, one of the study’s senior authors. He added that how a claim is written often matters more to the model than whether it is accurate.
Some of the accepted misinformation could pose real risks to patients. Several models endorsed claims such as Tylenol causing autism during pregnancy, rectal garlic boosting immunity, mammograms causing cancer, and tomatoes thinning blood as effectively as prescription medication. In another case, a discharge note incorrectly advised patients with oesophageal bleeding to drink cold milk, which some models repeated without flagging safety concerns.
The study also tested how AI systems responded to flawed arguments known as fallacies. While many fallacies prompted scepticism, models were more likely to accept false claims framed as expert opinions or warnings of catastrophic outcomes.
Researchers say future work should focus on measuring how often AI systems pass on falsehoods before they are used in clinical settings. Mahmud Omar, the study’s first author, said the dataset could help developers and hospitals stress-test AI tools and track improvements over time.
The authors said stronger safeguards will be essential as AI becomes more deeply embedded in healthcare decision-making.
Health
Moderate Caffeine Intake Linked to Lower Dementia Risk, Study Finds
Health
Growing Research Links Tattoos to Possible Cancer Risks, Experts Say
Tattoos are more popular than ever, but a growing body of research suggests a connection between permanent ink and certain types of cancer. How concerned should the public be?
From tribal sleeves to lower-back butterflies, humans have been inking their skin for thousands of years. For most, the main concern has been the fear of future regrets. However, recent studies suggest that tattoos could carry more serious long-term health risks.
The popularity of tattoos has risen sharply in recent years. Research published in the European Journal of Public Health estimates that between 13 and 21 percent of people in Western Europe now have at least one tattoo. Despite this prevalence, relatively little is known about the potential long-term effects of permanent ink.
Previous studies have shown that tattoo pigments can accumulate in the lymph nodes, sometimes causing inflammation and, in rare cases, lymphoma—a type of blood cancer. A 2025 study by the University of Southern Denmark (SDU) expanded on this, reporting that individuals with tattoos may face higher risks of skin cancer and lymphoma. Using a cohort of randomly selected twins, the researchers found that tattooed participants had nearly four times the risk of skin cancer compared with their non-tattooed siblings.
The study also suggested that tattoo size could affect risk, with designs larger than the palm associated with higher hazard rates.
“We have evidence that there is an association [between the amount of ink and risk] for lymphoma and for skin cancer,” said Signe Bedsted Clemmensen, co-author of the study and assistant professor of biostatistics at SDU. “For lymphoma, the hazard rate is 2.7 times higher, so this is quite a lot. And for skin cancers, before it was 1.6 and now it’s 2.4. This indicates that the more ink you have, the higher the risk, the higher the hazard rate.”
Clemmensen emphasized that these findings remain preliminary, with many variables—including ink types, tattoo placement, and genetic and environmental factors—still under investigation. “The bottom line is, more research is needed,” she said. “But also, the next step I think is studying the biological mechanisms [of getting tattooed] and trying to understand what happens there.”
Experts also note other risks unrelated to cancer. Tattoo inks consist of pigments combined with a carrier fluid to deposit color into the dermis. Some inks, often imported, can contain trace amounts of heavy metals such as nickel, chromium, cobalt, and lead, which can trigger allergic reactions or immune sensitivity. In 2022, the European Union restricted more than 4,000 hazardous substances in tattoo inks under its REACH regulations.
While tattoos are generally considered safe when applied hygienically, the long-term health consequences remain uncertain. “It’s up to each of us how we choose to live our lives, right? But as a researcher, it’s also my job to inform people of these risks,” Clemmensen said. “Or, when it comes to tattooing, right now it’s more about informing people about how little we know.”
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