Health
EU Food Safety Agency Lowers Safe Fluoride Intake Amid Concerns Over Children’s Brain Development
The European Food Safety Authority (EFSA) has issued new guidance lowering the safe daily intake of fluoride, amid growing concerns that even low levels of exposure may impact children’s brain development.
In a comprehensive reassessment, EFSA said there is currently no strong evidence of serious health risks from fluoride at levels typically found in EU drinking water. However, the agency acknowledged that new scientific findings suggest possible links between fluoride exposure and lower IQ in children, prompting it to lower recommended safety thresholds.
Fluoride is a naturally occurring mineral widely known for its role in preventing tooth decay. While only a few European countries, including Ireland and parts of Spain, actively add fluoride to public water supplies, the substance is present in roughly 90% of toothpaste brands. Most EU drinking water contains fluoride concentrations below 0.3 milligrams per litre (mg/L), well within the bloc’s legal limit of 1.5 mg/L and the same maximum recommended by the World Health Organization (WHO).
Despite these low levels, EFSA’s new review—which analyzed over 20,000 scientific studies—raises fresh questions. Experts reviewed fluoride’s potential effects on the developing brain, bones, thyroid function, and dental health through common sources such as water, food, fluoridated salt, and dental care products.
“We estimated that, in general, with the current concentrations of fluoride in European drinking water, total fluoride exposure does not pose a health concern,” said EFSA toxicologist Susanne Hougaard Bennekou. However, she noted that children aged four to eight who regularly swallow toothpaste could face mild tooth discoloration, particularly in their developing molars. “This is unlikely to occur if children spit the toothpaste out properly after brushing,” she added.
In response to the findings, EFSA introduced new safe daily intake thresholds:
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1 mg/day for infants under one year
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1.6 mg/day for toddlers aged one to three
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2 mg/day for children aged four to eight
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3.3 mg/day for older children and adults, including pregnant women
These new recommendations aim to protect against potential risks to brain development, thyroid function, and bone health. While they currently serve as part of a consumer safety guideline, they may influence future revisions to EU regulations on fluoride in drinking water.
Still, experts say more research is needed. “There is evidence that we can’t ignore linking fluoride to possible effects on the developing nervous system of the foetus,” said Thorhallur Halldorsson, chair of EFSA’s working group on fluoride. “But the evidence is not yet strong enough to set a definitive threshold.”
The findings could renew debate across Europe on the use of fluoride in public health, especially as governments weigh the benefits of dental protection against emerging concerns over long-term neurological effects.
Health
Study Finds AI Systems Can Repeat Fake Medical Claims When Framed Credibly
“Large language models accept fake medical claims if presented as realistic in medical notes and social media discussions, a study has found.”
As more people turn to the internet to research symptoms, compare treatments and share personal health experiences, artificial intelligence tools are increasingly being used to answer medical questions. A new study warns that many of these systems remain vulnerable to medical misinformation, particularly when false claims are presented in authoritative or realistic language.
The findings, published in The Lancet Digital Health, show that leading artificial intelligence systems can mistakenly repeat incorrect medical information when it appears in formats that resemble professional healthcare documents or trusted online discussions. Researchers analysed how large language models respond when faced with false medical statements written in a credible tone.
The study examined responses from 20 widely used language models, including systems developed by OpenAI, Meta, Google, Microsoft, Alibaba and Mistral AI, as well as several models specifically fine-tuned for medical use. In total, researchers assessed more than one million prompts designed to test whether AI would accept or reject fabricated health information.
Fake statements were inserted into real hospital discharge notes, drawn from common health myths shared on Reddit, or embedded in simulated clinical scenarios written to resemble authentic healthcare guidance. Across all models tested, incorrect information was accepted around 32 percent of the time. Performance varied significantly, with smaller or less advanced models accepting false claims in more than 60 percent of cases, while more advanced systems, including ChatGPT-4o, did so in roughly 10 percent of responses.
The researchers also found that medical fine-tuned models performed worse than general-purpose systems, raising concerns about tools designed specifically for healthcare use.
“Our findings show that current AI systems can treat confident medical language as true by default, even when it’s clearly wrong,” said Eyal Klang of the Icahn School of Medicine at Mount Sinai, one of the study’s senior authors. He added that how a claim is written often matters more to the model than whether it is accurate.
Some of the accepted misinformation could pose real risks to patients. Several models endorsed claims such as Tylenol causing autism during pregnancy, rectal garlic boosting immunity, mammograms causing cancer, and tomatoes thinning blood as effectively as prescription medication. In another case, a discharge note incorrectly advised patients with oesophageal bleeding to drink cold milk, which some models repeated without flagging safety concerns.
The study also tested how AI systems responded to flawed arguments known as fallacies. While many fallacies prompted scepticism, models were more likely to accept false claims framed as expert opinions or warnings of catastrophic outcomes.
Researchers say future work should focus on measuring how often AI systems pass on falsehoods before they are used in clinical settings. Mahmud Omar, the study’s first author, said the dataset could help developers and hospitals stress-test AI tools and track improvements over time.
The authors said stronger safeguards will be essential as AI becomes more deeply embedded in healthcare decision-making.
Health
Moderate Caffeine Intake Linked to Lower Dementia Risk, Study Finds
Health
Growing Research Links Tattoos to Possible Cancer Risks, Experts Say
Tattoos are more popular than ever, but a growing body of research suggests a connection between permanent ink and certain types of cancer. How concerned should the public be?
From tribal sleeves to lower-back butterflies, humans have been inking their skin for thousands of years. For most, the main concern has been the fear of future regrets. However, recent studies suggest that tattoos could carry more serious long-term health risks.
The popularity of tattoos has risen sharply in recent years. Research published in the European Journal of Public Health estimates that between 13 and 21 percent of people in Western Europe now have at least one tattoo. Despite this prevalence, relatively little is known about the potential long-term effects of permanent ink.
Previous studies have shown that tattoo pigments can accumulate in the lymph nodes, sometimes causing inflammation and, in rare cases, lymphoma—a type of blood cancer. A 2025 study by the University of Southern Denmark (SDU) expanded on this, reporting that individuals with tattoos may face higher risks of skin cancer and lymphoma. Using a cohort of randomly selected twins, the researchers found that tattooed participants had nearly four times the risk of skin cancer compared with their non-tattooed siblings.
The study also suggested that tattoo size could affect risk, with designs larger than the palm associated with higher hazard rates.
“We have evidence that there is an association [between the amount of ink and risk] for lymphoma and for skin cancer,” said Signe Bedsted Clemmensen, co-author of the study and assistant professor of biostatistics at SDU. “For lymphoma, the hazard rate is 2.7 times higher, so this is quite a lot. And for skin cancers, before it was 1.6 and now it’s 2.4. This indicates that the more ink you have, the higher the risk, the higher the hazard rate.”
Clemmensen emphasized that these findings remain preliminary, with many variables—including ink types, tattoo placement, and genetic and environmental factors—still under investigation. “The bottom line is, more research is needed,” she said. “But also, the next step I think is studying the biological mechanisms [of getting tattooed] and trying to understand what happens there.”
Experts also note other risks unrelated to cancer. Tattoo inks consist of pigments combined with a carrier fluid to deposit color into the dermis. Some inks, often imported, can contain trace amounts of heavy metals such as nickel, chromium, cobalt, and lead, which can trigger allergic reactions or immune sensitivity. In 2022, the European Union restricted more than 4,000 hazardous substances in tattoo inks under its REACH regulations.
While tattoos are generally considered safe when applied hygienically, the long-term health consequences remain uncertain. “It’s up to each of us how we choose to live our lives, right? But as a researcher, it’s also my job to inform people of these risks,” Clemmensen said. “Or, when it comes to tattooing, right now it’s more about informing people about how little we know.”
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