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AI Tool Uses Facial Ageing to Help Predict Cancer Survival

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Researchers in the United States have developed an artificial intelligence system that uses changes in facial appearance over time to help predict how cancer patients may respond to treatment and their chances of survival.

The tool, known as FaceAge, was created by scientists at Mass General Brigham. It estimates a person’s biological age from a photograph, offering a measure of how old the body appears physiologically rather than simply counting years since birth.

Biological age can differ from chronological age, as factors such as illness, stress and lifestyle often accelerate the ageing process. Researchers say facial features may provide important clues about a person’s overall health.

Earlier studies using FaceAge found that cancer patients typically appeared about five years older biologically than their actual age. Those with older-looking facial profiles were also more likely to experience poorer outcomes following treatment.

In the latest research, scientists introduced a new metric called Face Aging Rate, or FAR, which tracks changes in biological age over time by comparing multiple photographs. The method is designed to monitor how quickly a person appears to age, potentially offering a real-time indicator of health.

The study analysed images of 2,276 cancer patients treated at Brigham and Women’s Hospital between 2012 and 2023. All participants had undergone at least two courses of radiation therapy, with photographs taken routinely during their treatment.

Researchers found that, on average, patients’ facial ageing progressed about 40% faster than their actual chronological ageing. Those with higher FAR scores had significantly lower survival rates, particularly when the photographs were taken more than two years apart.

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The findings suggest that changes in facial appearance over time may provide valuable insight into a patient’s condition and long-term prognosis.

The study also examined FaceAge Deviation, a separate measure comparing biological age from a single photograph with a person’s actual age. While higher scores were also linked to poorer outcomes, FAR proved to be a stronger and more reliable predictor of survival over extended periods.

Researchers believe combining both measures could offer a more complete picture of a patient’s health and disease progression.

Dr Raymond Mak, a radiation oncologist at Mass General Brigham Cancer Institute, said the technology could help doctors refine treatment plans, improve patient counselling and determine the most appropriate follow-up care.

The team also sees broader potential beyond oncology. Future research will explore whether the technology could help assess other chronic illnesses or even provide early health insights for otherwise healthy individuals.

To support ongoing studies, researchers have launched a public web portal where users can upload a photograph, receive a FaceAge estimate and contribute data to further development of the tool.

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AI Tool Shows Promise in Detecting ADHD Risk Years Before Diagnosis

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Artificial intelligence could soon help doctors identify children at risk of attention-deficit/hyperactivity disorder (ADHD) years before they receive a formal diagnosis, according to new research that could transform early intervention for one of childhood’s most common neurodevelopmental disorders.

The study, conducted by researchers at Duke Health and published in Nature Mental Health, found that AI can analyse routine electronic health records to detect early warning signs of ADHD long before symptoms typically lead to a diagnosis.

ADHD affects an estimated 8% of children and adolescents. It is characterised by symptoms such as difficulty concentrating, impulsivity, restlessness and problems with organisation. Despite its prevalence, many children are not diagnosed until years after symptoms first appear, delaying access to treatment and support.

Researchers examined health records from more than 140,000 children, including both those diagnosed with ADHD and those without the condition. Using data collected from birth through early childhood, the AI model was trained to identify patterns linked to later ADHD diagnoses.

The system successfully recognised combinations of developmental, behavioural and clinical indicators that often emerged years before a formal diagnosis. It was particularly accurate in assessing risk among children aged five and older, and its performance remained consistent across sex, race, ethnicity and insurance status.

Elliot Hill, the study’s lead author and a data scientist at Duke University School of Medicine, said electronic health records contain a wealth of information that can reveal important patterns.

The researchers believe the technology could help clinicians identify children who may benefit from earlier assessment, allowing families to access support sooner. Early intervention has been shown to improve academic performance, social development and long-term health outcomes.

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Naomi Davis, an associate professor in Duke’s Department of Psychiatry and Behavioral Sciences and a co-author of the study, said timely support is critical for children with ADHD.

“Children with ADHD can really struggle when their needs aren’t understood and adequate supports are not in place,” she said.

The research team stressed that the tool is not intended to replace doctors or provide a definitive diagnosis. Instead, it is designed to assist clinicians by highlighting children who may require further evaluation.

Matthew Engelhard, senior author of the study, described it as a way to ensure that children who need help are identified earlier and do not face unnecessary delays.

Experts say the approach could eventually be expanded to other areas of mental health, with similar AI models already being explored to better understand psychiatric risks in adolescents.

The findings also highlight the potential to improve recognition of ADHD in girls, who are often underdiagnosed because their symptoms tend to be less overt than those seen in boys.

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Baby Food Recall Across Europe After Suspected Tampering Contamination

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Authorities in Central Europe have ordered the recall of baby food products from organic manufacturer HiPP after several jars were found to contain a toxic substance believed to be rodenticide, raising serious safety concerns.

The affected products, 190-gram jars of carrot and potato baby food intended for infants aged five months and older, were sold through SPAR stores in Austria and distributed in parts of Slovakia and the Czech Republic. Austrian officials confirmed the contamination on April 19, following initial positive test results a day earlier.

Investigators believe the case is the result of deliberate tampering rather than a failure in manufacturing. In a statement, HiPP said the products left its facilities in proper condition and described the incident as a “criminal act” currently under investigation.

The alert was triggered after a customer reported a jar that appeared to have been interfered with. So far, no cases of consumption or illness linked to the contaminated products have been reported.

Police in Austria’s Burgenland region have urged parents to examine any recently purchased jars. Warning signs include damaged or already-opened lids, unusual smells, missing sealing “pop” sounds when opened, and suspicious markings such as a white sticker with a red circle on the base.

The Austrian Agency for Health and Food Safety said the substance detected is likely bromadiolone, a chemical commonly used in rat poison. It works by preventing blood from clotting and can lead to internal bleeding, posing a serious risk, especially to infants.

Health officials warned that symptoms may not appear immediately, with signs potentially emerging between two and five days after ingestion. These may include bleeding gums, nosebleeds, unexplained bruising, or blood in stool. Treatment is available and typically involves administering vitamin K.

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As a precaution, HiPP has recalled all its baby food jars from SPAR outlets in Austria, including EUROSPAR, INTERSPAR and Maximarkt stores. Customers have been advised to return the products for a full refund, with no receipt required.

Retailers in Slovakia and the Czech Republic have also removed HiPP baby food products from shelves, although no further confirmed contamination cases have been reported in those countries.

The investigation into the source of the tampering remains ongoing, with no suspects identified so far.

The incident comes amid heightened concern over infant food safety. Earlier this year, companies including Nestlé and Danone issued widespread recalls of baby formula products after reports of contamination and illness affecting children in multiple countries.

Authorities across Europe are continuing to monitor the situation closely as efforts intensify to ensure consumer safety and identify those responsible.

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Air Pollution Linked to Higher Cancer Risk and Death Rates, Report Warns

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A new global report has found that exposure to polluted air significantly increases the risk of developing and dying from a range of cancers, prompting renewed calls for stricter air quality standards worldwide.

The study, led by the Union for International Cancer Control with support from the Clean Air Fund, analysed findings from 42 meta-analyses and systematic reviews published between 2019 and 2024. Researchers concluded that air pollution is not only a major cause of lung cancer but is also strongly linked to other forms of the disease, including liver, breast, colorectal, kidney and bladder cancers.

According to the report, fine particulate matter known as PM2.5 poses the greatest threat. People exposed to high levels of these particles face an 11 percent higher overall risk of developing cancer compared to those in cleaner environments. Long-term exposure was also associated with a 12 percent increase in cancer-related deaths, with particularly sharp rises seen in breast, liver and lung cancer mortality.

Larger particles, classified as PM10, were also found to increase cancer risks. Exposure to these pollutants was linked to a 10 percent rise in overall cancer risk and higher death rates from both lung and breast cancers.

Experts behind the report stressed that the impact of air pollution extends far beyond respiratory illnesses. Helen Clark, co-chair of the Our Common Air initiative, said clean air should be treated as a fundamental human right tied to health, equality and sustainable development.

The findings also highlight significant inequalities in exposure and health outcomes. Women and children are often more vulnerable due to reliance on solid fuels for cooking and heating in many parts of the world. The report found that women exposed to household air pollution face a 69 percent higher risk of lung cancer, along with increased risks of other diseases.

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Communities in low- and middle-income countries bear the heaviest burden, as they are more likely to experience higher pollution levels while having limited access to healthcare. The report noted that disparities also exist within wealthier regions, with poorer communities often facing greater exposure to polluted environments.

Cary Adams said that while progress has been made in reducing cancer deaths globally, air pollution continues to undermine these gains. He described it as a risk that individuals cannot avoid and one that disproportionately affects vulnerable populations.

The report calls for stronger action to address the issue, including improved air quality monitoring and stricter environmental regulations. Elisabete Weiderpass of the International Agency for Research on Cancer said more research is needed to better understand how pollution contributes to cancers beyond the lungs, but added that existing evidence already justifies immediate action.

Researchers warned that reducing air pollution could have wide-ranging health benefits, including lowering rates of cancer as well as cardiovascular and respiratory diseases, reinforcing the urgency of tackling the problem.

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