Health
E-Cigarettes Found More Effective Than Patches and Gum for Quitting Smoking, Study Shows
E-cigarettes may help smokers quit more effectively than traditional methods such as patches and gum, according to a new study led by researchers at the University of Oxford. The study, published in the journal Addiction, also highlights ongoing health concerns associated with vaping.
The researchers analyzed 14 systematic reviews conducted between 2014 and 2023 to evaluate the effectiveness of nicotine e-cigarettes for smoking cessation. Their findings suggest that e-cigarettes outperform conventional nicotine replacement therapies. One 2024 Cochrane review cited in the study found that for every 100 users, an additional two to five people quit smoking when using nicotine e-cigarettes compared to using patches or gum.
Angela Difeng Wu, senior researcher and lecturer at the Nuffield Department of Primary Care Health Sciences at Oxford, said the evidence is “clear and consistent across all of the meta-analyses we consulted: e-cigarettes are effective at helping people stop smoking.” The team also developed an “Evidence and Gap Map” to highlight areas where further research is needed.
While e-cigarettes appear effective, the researchers noted that evidence on serious adverse events remains inconclusive. Most other side effects showed little or no difference between nicotine e-cigarettes and other cessation treatments. Experts caution that while vaping is less harmful than smoking combustible tobacco, it is not risk-free.
A February 2026 study found that e-cigarette users are exposed to carcinogenic chemicals, though at lower levels than smokers of traditional tobacco products. The long-term health impacts of e-cigarettes remain uncertain, partly because the products are relatively new and continue to evolve.
Despite their potential to reduce smoking, e-cigarettes have raised public health concerns, particularly among young people. The World Health Organization estimated in 2025 that over 100 million people worldwide use e-cigarettes, including at least 15 million children aged 13 to 15. In countries with available data, children are on average nine times more likely than adults to vape.
“E-cigarettes are fuelling a new wave of nicotine addiction,” said WHO’s Etienne Krug. “They are marketed as harm reduction but, in reality, are hooking kids on nicotine earlier and risk undermining decades of progress.”
The Oxford study emphasizes that uncertainties about e-cigarettes’ long-term effects and their role in smoking cessation continue to influence policy and clinical decision-making. Researchers stress that e-cigarettes should be considered as tools for current smokers attempting to quit, rather than products for non-smokers or young people.
The study contributes to the growing body of evidence supporting nicotine e-cigarettes as an alternative to traditional cessation methods, while underscoring the need for ongoing monitoring and regulation to prevent uptake among children and non-smokers.
Health
Global Mental Health Cases Near 1.2 Billion as Anxiety and Depression Drive Sharp Worldwide Rise
A major global analysis has found that mental health conditions have surged to an estimated 1.2 billion people worldwide, driven largely by steep increases in anxiety and depression over the past three decades.
The findings, published in The Lancet as part of the Global Burden of Disease Study 2023, show that the number of people living with mental disorders has almost doubled since 1990, marking a 95% rise. Researchers say major depressive disorder and anxiety disorders have seen even sharper growth, increasing by 131% and 158% respectively, making them the most prevalent mental health conditions globally.
The report describes mental illnesses as widespread conditions that create long-term disability and significant human suffering. It also highlights broader consequences for economies and public services, including reduced productivity, lower workforce participation and increasing pressure on health and welfare systems.
Researchers estimate that in 2023 alone, around 620 million females and 552 million males were affected by mental health conditions. While the overall burden is rising across both sexes, the study points to notable differences in the types and prevalence of disorders.
Among women, depression and anxiety were the most commonly reported conditions, alongside higher rates of eating disorders such as anorexia nervosa and bulimia nervosa. The report links this disparity to a mix of biological, social and structural factors, including exposure to domestic violence, sexual abuse, gender inequality and reproductive health-related changes.
In contrast, neurodevelopmental and behavioural disorders, including attention deficit hyperactivity disorder (ADHD), conduct disorder and autism spectrum conditions, were more frequently diagnosed in men.
Teenagers aged 15 to 19 were identified as the group experiencing the highest mental health burden globally, raising concerns about early onset of conditions and insufficient preventive care for young people.
The study identifies several key risk factors associated with mental illness, including childhood sexual violence, bullying and intimate partner violence. These factors are strongly linked to conditions such as depression, schizophrenia, bipolar disorder and anxiety disorders. However, researchers note that such exposures have remained relatively stable over time and account for only a portion of the overall rise.
According to the authors, broader drivers are likely contributing to the increasing prevalence of mental disorders. These include genetic and biological influences, poverty, inequality, and the growing impact of global crises such as armed conflict, pandemics, natural disasters and climate-related stress.
While mental health conditions have long been a leading cause of disability worldwide, the report warns that the situation is worsening. At the same time, health systems have not expanded services at a pace matching demand.
The authors caution that the gap between rising need and limited access to care is becoming more pronounced, leaving millions without adequate treatment or support.
Health
Europe Records Sharp Rise in Sexually Transmitted Infections, ECDC Warns
Health
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