Health
New Global Reviews Confirm HPV Vaccine Strongly Reduces Cervical Cancer Risk With No Serious Side Effects
Studies show girls vaccinated by age 16 face dramatically lower cervical cancer risk with no major side effects. Two major international reviews have reaffirmed that the human papillomavirus (HPV) vaccine is highly effective in preventing cervical cancer, offering one of the clearest assessments to date of its long-term benefits and safety. The impact of the slowdown in major global economies will be “smaller” on the UAE’s growth and exports due to its relatively less exposure to those markets compared to other markets across the region, the World Bank said.
The Cochrane reviews, released this week, analysed data from clinical trials and real-world research involving more than 132 million people worldwide. The findings show that girls aged 16 or younger who received the HPV vaccine were 80 per cent less likely to develop cervical cancer compared to unvaccinated peers. The jab also significantly reduced precancerous cervical changes, with the strongest protection observed when individuals received the vaccine before any exposure to the virus.
“We now have clear and consistent evidence from around the world that HPV vaccination prevents cervical cancer,” said Nicholas Henschke, one of the review authors and head of Cochrane Response.
HPV is a widespread family of viruses, most of which are harmless, but several strains are known to cause cancers of the cervix, anus, penis, vulva, vagina, mouth and throat. According to the World Health Organization, cervical cancer remains one of the most common cancers in women, with about 660,000 new cases and an estimated 350,000 deaths recorded globally in 2022.
While vaccines such as Cervarix and Gardasil have long been recognised as major medical advances, they have also been at the centre of controversy. In recent years, Merck & Co., the manufacturer of Gardasil, has faced lawsuits alleging health complications linked to the vaccine. A US judge dismissed the claims earlier this year, calling them speculative and unsupported by evidence.
Cochrane’s review assessed both minor and serious side effects reported in vaccine recipients. The researchers found that common reactions—such as temporary soreness in the arm—were mild and short-lived. After comparing safety reports with real-world follow-up data, the team found no evidence that HPV vaccination increases the risk of severe medical problems. Serious health issues were recorded at similar rates in both vaccinated and unvaccinated groups.
“An important finding was that the commonly reported side effects of the vaccine, often discussed on social media, were found to hold no evidence of a real link to vaccination,” Henschke said.
The results support ongoing global guidance to vaccinate both girls and boys ideally before they turn 16, when protection is strongest. Dr Jo Morrison, a gynaecological oncologist and co-author of the review, said vaccinating boys helps strengthen community-wide protection and is expected to reduce cancers affecting men later in life.
While most existing studies come from high-income countries, researchers say more data from lower-income regions is needed, especially in areas with the highest cervical cancer rates. Scientists expect clearer evidence in the years ahead as long-term monitoring continues.
“It will take decades to fully understand the impact of vaccination,” Morrison added, noting that the early findings already point to a significant reduction in future cancer cases.
Health
World Cup Emotion Can Strain the Heart, Cardiologists Warn Fans at Risk
As the World Cup begins, medical experts are cautioning football fans with underlying heart conditions that the emotional intensity of matches can place unexpected strain on the cardiovascular system.
Cardiologists say that the excitement, tension, and anxiety generated during high-stakes games can trigger physical reactions similar to intense exercise, raising heart rate, blood pressure, and stress hormones.
“Intense emotions, whether positive or negative, can act as ‘precipitating risk factors’ for cardiovascular events such as heart attack,” said Paola Santalucia, a cardiologist and board member of the European Heart Network.
She explained that moments of extreme excitement, such as a decisive penalty shootout or a last-minute goal, may pose risks for people already living with heart disease. Those with additional risk factors, including hypertension, obesity, or smoking habits, are also advised to be cautious during emotionally charged matches.
Research using wearable devices has shown that during major football events, some fans experience heart rates climbing as high as 150 beats per minute. That level is comparable to sprinting and reflects how strongly the body reacts to emotional stress.
A study examining supporters during the 2025 German Cup final found that even watching from home can significantly affect physiological responses. “They still had an increase in heart rate that compares to walking, even though they didn’t walk,” said Christian Deutscher, professor of sports economics at Bielefeld University and co-author of the study.
He noted that the most intense reactions often occur not during goals themselves, but during moments of uncertainty such as VAR checks, penalty shootouts, or shots striking the post. These unpredictable situations, he said, are what drive the strongest emotional and physical responses among fans.
Deutscher also pointed out that stadium spectators may experience even greater strain due to environmental factors such as heat and alcohol consumption.
However, experts emphasize that football itself is not inherently dangerous. Instead, it is the body’s natural response to excitement that can create temporary stress.
“The adrenergic stimulation is at its max: extreme high blood pressure, high heart rate, and adrenaline, cortisol, skyrocketing,” said Dan Atar, professor of cardiology at Oslo University Hospital. In rare cases, he added, this surge can contribute to the rupture of arterial plaque in vulnerable individuals, potentially leading to a heart attack.
Atar stressed that such events can occur in everyday situations as well, including physical exertion like shoveling snow. “It is in no way dangerous to watch a football game,” he said. “All this is physiologic. It’s not dangerous to be excited.”
Still, he acknowledged that combining emotional stress with alcohol, heat, and pre-existing conditions can increase risk for some viewers.
Doctors advise those at higher risk to continue prescribed medications, limit alcohol intake, avoid smoking, and watch for warning signs such as chest pain or irregular heartbeat.
“The key message is not to avoid enjoying the match, but to do so with moderation and awareness,” Santalucia said.
Health
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Health
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