Health
Experimental Alzheimer’s Drug Shows Promise in Reducing Dementia Risk
A new experimental treatment targeting amyloid plaques in the brain has shown promising early results in reducing the risk of Alzheimer’s-related dementia among asymptomatic patients. The drug, gantenerumab, was studied in a small group of individuals genetically predisposed to the neurodegenerative disease.
Researchers tracked 22 patients with genetic mutations that cause an overproduction of amyloid, a protein that clumps together to form plaques in the brain, a hallmark of Alzheimer’s disease. According to findings published in Lancet Neurology, participants who took gantenerumab for eight years saw their risk of developing symptoms drop from 100% to approximately 50%.
Long-Term Treatment May Be Key
The study’s lead author, Randall Bateman, a professor of neurology at Washington University School of Medicine in the U.S., emphasized the significance of the results. “Everyone in this study was destined to develop Alzheimer’s disease, and some of them haven’t yet,” Bateman said. “To give them the best opportunity to stay cognitively normal, we have continued treatment with another anti-amyloid antibody in hopes they will never develop symptoms at all.”
Notably, cognitive benefits were observed only in patients who received the treatment for the full eight years. Those who were treated for only two to three years did not show noticeable improvements, suggesting that long-term preventive therapy may be necessary for effectiveness.
Challenges and Limitations
Despite the encouraging results, experts have pointed out limitations in the study. Charles Marshall, a professor of clinical neurology at Queen Mary University of London, called the findings “very exciting” but noted that the study involved a small number of participants and was a secondary evaluation rather than a primary clinical trial.
Another concern is that gantenerumab is not as effective as some newer amyloid-reducing treatments, suggesting there may be even better options available. The drug was discontinued in 2022 after failing to slow symptoms in a trial involving over 1,900 participants with more common forms of Alzheimer’s disease.
Future Research Needed
While gantenerumab has shown potential in genetically predisposed individuals, further research is required to determine the optimal treatment duration, the effects on non-genetic cases of Alzheimer’s, and possible side effects. Some anti-amyloid drugs have been linked to brain abnormalities and localized swelling, though most side effects resolve on their own. In the study, two participants had to stop taking the drug due to side effects, but no life-threatening adverse effects were reported.
The findings contribute to the growing body of research on anti-amyloid therapies, highlighting the need for continued investigation into more effective Alzheimer’s prevention and treatment strategies.
Health
FDA Clears AI Tool to Improve Detection of Fetal Abnormalities in Ultrasounds
A new artificial intelligence software designed to enhance prenatal ultrasound screenings has received clearance from the United States Food and Drug Administration (FDA), offering a potential boost to the detection of fetal abnormalities.
Developed by the American start-up BioticsAI, the tool integrates with existing ultrasound machines to analyze images in real time, highlighting potential issues during scans. Prenatal ultrasounds are widely used throughout pregnancy to identify potential problems in a developing fetus, including malformations in organs or limbs. Yet studies suggest that routine scans can miss a significant number of abnormalities.
According to research, a single early scan performed between 11 and 14 weeks of pregnancy detects only about 38 percent of birth defects. A mid-pregnancy scan, typically conducted between 18 and 24 weeks, identifies roughly 51 percent of abnormalities. When both scans are performed, detection rises to 84 percent, leaving a remaining gap in diagnosis.
BioticsAI’s software works by analyzing each fetal image as it is captured. It evaluates image quality, suggesting adjustments to ensure a clear view of the fetus, and checks whether all parts of the baby are visible. Using data patterns drawn from a global database, the system can detect anomalies, including heart or limb defects, and flag them for the doctor during the scan. After the examination, the software generates a report compiling all findings for clinical review.
Developers say the tool can also save healthcare professionals roughly eight minutes per patient in documentation time. The FDA’s clearance confirms that the software meets medical device performance standards and can be safely integrated into current ultrasound systems.
The approval comes amid ongoing challenges in prenatal care. In Europe, major congenital anomalies occur in about 23.9 per 10,000 births. AI-driven tools are emerging as a promising supplement to conventional scans. French companies Diagnoly and Sonio Detect have also received approval for AI-assisted ultrasound solutions, which automatically identify fetal structures and detect potential heart issues.
Experts say integrating AI into prenatal care could improve early detection rates and help doctors provide timely interventions or monitoring. Real-time feedback during scans ensures that images are complete and abnormalities are less likely to be missed.
BioticsAI’s FDA-cleared tool is expected to be rolled out in clinics across the United States, offering clinicians an additional layer of support in detecting congenital abnormalities. As AI technologies continue to expand in healthcare, prenatal care is emerging as a key area where machine learning can complement human expertise, improving outcomes for both mothers and babies.
Health
Early Flu Wave Hits Europe as Experts Offer Tips to Ease Symptoms
Most people catch a cold in winter, battling fatigue, runny noses, sneezes, coughs, and congestion. This season, an unusually early flu wave has affected millions across Europe, prompting health authorities to offer guidance on managing symptoms.
Typically, influenza season runs from mid-November to late May. However, figures from the European Centre for Disease Prevention and Control (ECDC) indicate that cases in 2025 surged three to four weeks earlier than in the previous two seasons. The agency reports that flu circulation remains high, though it has recently peaked in most regions.
While there are no specific cures for the flu and the common cold, some simple measures can help manage symptoms and improve comfort. Experts recommend a combination of hydration, rest, and symptom relief to support recovery.
Drinking enough fluids is particularly important. Water, broths, and warm beverages with honey, lemon, or ginger can help prevent dehydration, loosen mucus, and soothe irritated airways. Health authorities caution against alcohol, coffee, and other caffeinated drinks, which can act as diuretics and worsen congestion and sore throats.
Gargling with warm salt water is another simple measure to ease throat pain and reduce inflammation. Mixing one teaspoon of salt in a cup of warm water and using it several times a day can provide relief and help clear mucus.
Rest is essential for recovery. Adults are advised to sleep seven to nine hours a night, and to take naps as needed to allow the immune system to combat the virus. Light exercise such as short walks or yoga may be suitable for mild symptoms, but physical activity should be avoided if fever is present or chest symptoms worsen, to prevent complications.
Maintaining moisture in the environment can also alleviate symptoms. Dry air worsens congestion and sore throats, while humidified air hydrates airways and helps clear mucus. Higher humidity can also reduce how long some respiratory viruses survive in the air.
Medicines can relieve symptoms but do not cure viral infections. Decongestants, such as saline sprays or drops, can ease nasal congestion. Painkillers, including ibuprofen, may reduce fever and discomfort in adults. Antibiotics are not effective against colds or flu and should be avoided to prevent antibiotic resistance.
Health authorities emphasize that these measures, combined with good hygiene and vaccination where appropriate, are key to limiting the impact of seasonal viruses. The ECDC notes that most healthy adults recover from flu within about a week, while a common cold may last up to two weeks.
With the early flu wave affecting millions across Europe, simple steps such as staying hydrated, resting, and taking appropriate symptom relief can help patients recover safely and reduce strain on healthcare services.
Health
Climate Change Drives Respiratory Illness, Push for Low-Carbon Inhalers Grows
As climate change worsens respiratory diseases, doctors and drugmakers are exploring earlier diagnosis and low-carbon inhalers to cut emissions from care and protect patients.
For millions of people worldwide, climate change is already affecting breathing. Rising air pollution, longer pollen seasons, and smoke from wildfires are contributing to asthma attacks, lung damage, and other chronic respiratory illnesses. At the same time, the health systems treating these conditions are themselves contributing to greenhouse gas emissions.
Experts note that over 90 percent of the global population breathe air with particulate levels above World Health Organization recommendations. Climate extremes and poor air quality are increasing the frequency and severity of respiratory diseases, from exacerbations to disease onset. Therese Laperre, head of the respiratory department at University Hospital Antwerp, said changes in particulate matter can trigger emergency visits for asthma and chronic pulmonary diseases days later. A European Environment Agency study estimated that more than a third of chronic respiratory disease deaths in Europe are linked to environmental factors such as pollution, extreme temperatures, wildfire smoke, and allergenic pollen.
Worldwide, an estimated 400 to 500 million adults live with COPD, and over 250 million have asthma. Health care responses come with their own climate cost. Health Care Without Harm estimates global health services generate about five percent of worldwide greenhouse gas emissions, which could rise to six gigatons annually by 2050 if unchecked, equivalent to more than a billion cars on the road. Hospitals, particularly intensive care units, are among the most carbon-intensive, due to high energy use, equipment, and single-use materials.
Respiratory specialists emphasize that early disease control benefits both patients and the environment. Philippe Tieghem from the French respiratory association Sante Respiratoire said early diagnosis allows for better patient care while reducing emissions.
Inhalers, commonly used to treat asthma and COPD, illustrate the challenge. Traditional pressurised metered-dose inhalers (pMDIs) use hydrofluorocarbon propellants, which contribute 16–17 million tonnes of CO₂-equivalent emissions globally each year. The UK’s National Health Service estimates these inhalers account for around three percent of its carbon footprint.
Pharmaceutical companies are developing greener alternatives. AstraZeneca’s reformulated COPD inhaler uses a new propellant, HFO‑1234ze(E), cutting its global warming potential by roughly 99.9 percent compared with older devices. The company has pledged to reduce its emissions by 98 percent by 2026, starting with inhalers. Pfizer and Johnson & Johnson have committed to net-zero targets by 2040 and 2045, respectively.
Pablo Panella, senior vice-president for respiratory diseases at AstraZeneca, told Euronews Health that early detection, diagnosis, and treatment keep patients controlled in the community, reducing hospital admissions and the high-carbon interventions that come with them. Panella also stressed the importance of regulation that supports innovation, allowing low-carbon technologies to reach patients more quickly.
Better disease control, combined with environmentally conscious products, is creating the concept of the “green patient”: someone whose chronic condition is managed well enough to avoid repeated flare-ups, hospital stays, and carbon-intensive treatments.
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