Health
Study Finds One-Third of Global Cancer Cases Could Be Prevented by Controlling Risk Factors
A new study published in Nature Medicine on Tuesday shows that nearly 40 percent of new cancer cases worldwide could be prevented by managing common risk factors such as smoking, alcohol use, and infections. The research, released ahead of World Cancer Day, analyzed 36 types of cancer across 185 countries using data from 2022 and examined 30 modifiable risk factors that can be controlled or managed to reduce the likelihood of developing the disease.
The study found that tobacco use remains the leading contributor to cancer globally, followed by infections and alcohol consumption. Out of the 18.7 million new cancer cases recorded in 2022, about 7.1 million, or 38 percent, were linked to preventable causes. Stomach, lung, and cervical cancers accounted for nearly half of these avoidable cases.
Smoking was responsible for approximately 15 percent of preventable cancers, making it the single largest risk factor worldwide. Infections, including human papillomavirus (HPV), contributed to around 10 percent of cases, while alcohol consumption accounted for three percent.
Regional differences were evident in the data. In low- and middle-income regions, such as sub-Saharan Africa, infections were the leading contributor to preventable cancers, with cervical cancer being particularly prevalent. In contrast, in high-income regions such as Europe and North America, smoking was the primary factor driving cancer cases among women. Smoking also remained the top risk factor among men globally, responsible for nearly 25 percent of 4.3 million avoidable cases. Infections were the second leading cause of cancer among men, especially in Asia, Africa, and South America.
Among the 9.2 million new cancer cases in women, roughly 30 percent were considered preventable. Infections such as HPV were linked to over 11 percent of these cases, highlighting the importance of vaccination and early detection programs in vulnerable regions.
The research also considered population-level exposure to each risk factor, showing how the number of cases varied across regions based on lifestyle, healthcare access, and public health interventions. Previous studies often focused on single risk factors or mortality, but this study provides a more comprehensive view of cancer incidence globally and the proportion that could be avoided through preventive measures.
Researchers say the findings could help guide more targeted cancer prevention strategies. By identifying the most significant risk factors in different regions, policymakers and health organizations can design interventions tailored to local needs rather than applying a one-size-fits-all approach.
“This study underscores the potential for prevention in reducing the global burden of cancer,” the authors said. “Addressing smoking, infections, and alcohol consumption could prevent millions of cases each year and save countless lives.”
Health
World Cup Emotion Can Strain the Heart, Cardiologists Warn Fans at Risk
As the World Cup begins, medical experts are cautioning football fans with underlying heart conditions that the emotional intensity of matches can place unexpected strain on the cardiovascular system.
Cardiologists say that the excitement, tension, and anxiety generated during high-stakes games can trigger physical reactions similar to intense exercise, raising heart rate, blood pressure, and stress hormones.
“Intense emotions, whether positive or negative, can act as ‘precipitating risk factors’ for cardiovascular events such as heart attack,” said Paola Santalucia, a cardiologist and board member of the European Heart Network.
She explained that moments of extreme excitement, such as a decisive penalty shootout or a last-minute goal, may pose risks for people already living with heart disease. Those with additional risk factors, including hypertension, obesity, or smoking habits, are also advised to be cautious during emotionally charged matches.
Research using wearable devices has shown that during major football events, some fans experience heart rates climbing as high as 150 beats per minute. That level is comparable to sprinting and reflects how strongly the body reacts to emotional stress.
A study examining supporters during the 2025 German Cup final found that even watching from home can significantly affect physiological responses. “They still had an increase in heart rate that compares to walking, even though they didn’t walk,” said Christian Deutscher, professor of sports economics at Bielefeld University and co-author of the study.
He noted that the most intense reactions often occur not during goals themselves, but during moments of uncertainty such as VAR checks, penalty shootouts, or shots striking the post. These unpredictable situations, he said, are what drive the strongest emotional and physical responses among fans.
Deutscher also pointed out that stadium spectators may experience even greater strain due to environmental factors such as heat and alcohol consumption.
However, experts emphasize that football itself is not inherently dangerous. Instead, it is the body’s natural response to excitement that can create temporary stress.
“The adrenergic stimulation is at its max: extreme high blood pressure, high heart rate, and adrenaline, cortisol, skyrocketing,” said Dan Atar, professor of cardiology at Oslo University Hospital. In rare cases, he added, this surge can contribute to the rupture of arterial plaque in vulnerable individuals, potentially leading to a heart attack.
Atar stressed that such events can occur in everyday situations as well, including physical exertion like shoveling snow. “It is in no way dangerous to watch a football game,” he said. “All this is physiologic. It’s not dangerous to be excited.”
Still, he acknowledged that combining emotional stress with alcohol, heat, and pre-existing conditions can increase risk for some viewers.
Doctors advise those at higher risk to continue prescribed medications, limit alcohol intake, avoid smoking, and watch for warning signs such as chest pain or irregular heartbeat.
“The key message is not to avoid enjoying the match, but to do so with moderation and awareness,” Santalucia said.
Health
AI Models Show Ability to Mimic Human Emotions, Offering New Pathways for Mental Health Research
Health
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