Health
UNAIDS Chief Warns of HIV Surge if US Funding is Cut
The global fight against HIV and AIDS could suffer a devastating setback if the United States withdraws its financial support, potentially leading to a sixfold increase in new infections, UNAIDS Executive Director Winnie Byanyima warned on Monday.
Speaking from Uganda, Byanyima told the Associated Press that millions of lives are at risk, and the world could see a resurgence of drug-resistant strains of the virus if crucial funding is not maintained.
According to UNAIDS estimates, 39.9 million people worldwide are currently living with HIV, with 1.3 million new infections recorded in 2023. Since the peak of the epidemic in 1995, new cases have dropped by 60%, largely due to international efforts, including significant US contributions.
However, with former US President Donald Trump announcing a 90-day freeze on all foreign aid, UNAIDS officials predict that by 2029, new infections could soar to 8.7 million, and AIDS-related deaths could rise tenfold to 6.3 million. Additionally, an estimated 3.4 million children could be orphaned due to the crisis.
Fear and Uncertainty in Affected Countries
Byanyima described the abrupt funding freeze as a “crisis” that has triggered panic, fear, and confusion in African countries hardest hit by the epidemic. In one Kenyan county alone, 550 HIV healthcare workers were laid off immediately, while thousands of Ethiopian health professionals also lost their jobs, leaving officials unable to track and manage the disease effectively.
“The loss of US funding is catastrophic,” Byanyima said, noting that in some countries, up to 90% of HIV programmes are funded by external donors, primarily the United States. The potential loss amounts to nearly $400 million (€384 million) for HIV programmes in countries like Uganda, Mozambique, and Tanzania.
A Call for Global Action
Byanyima urged Washington to reconsider, emphasizing that while the US might seek to reduce its financial commitment, a gradual transition would be far less damaging than an abrupt withdrawal.
“We can work with [the Americans] on how to decrease their contribution if they wish to decrease it,” she said.
She called the potential loss of US support the second-biggest crisis the global HIV response has faced—after the long delay in making life-saving antiretroviral treatments available in low-income countries.
Will Europe Step In?
So far, no other major donor has pledged to fill the funding gap. Byanyima said she plans to visit several European capitals to push for urgent financial commitments, hoping that countries that prioritize human rights and global health will step in.
“People are going to die because lifesaving tools have been taken away from them,” she warned.
“I have not yet heard of any European country committing to step in, but I know that they are listening and trying to see where they can come in because they care about rights, about humanity.”
With time running out, global leaders will need to decide whether they can afford to let one of the world’s most significant public health battles slide backward.
Health
Medieval Manuscripts Reveal Thousands-Year History of Deadly Sheep Virus
DNA recovered from medieval manuscripts has given scientists new clues about the long history of sheep pox, a highly contagious disease that has threatened livestock for thousands of years.
An international team led by researchers at University College Dublin discovered traces of sheep pox virus in parchment used for some of Europe’s historic manuscripts. The findings suggest that animal diseases may have left genetic records in old documents, providing scientists with another way to study how pathogens developed over time.
During the Middle Ages, parchment was commonly made from the treated skin of sheep, goats and cattle. Researchers extracted DNA from the animal skins used to produce centuries-old manuscripts and identified genetic material linked to the sheep pox virus.
The study involved geneticists, historians, virologists, protein chemists and conservation specialists. Louis L’Hôte, the study’s lead author, said the research showed that parchment could preserve DNA from animal pathogens and provide valuable evidence about infectious diseases in the past.
Among the manuscripts examined was the approximately 1,000-year-old York Gospels, considered one of the finest surviving illuminated manuscripts from the late Anglo-Saxon period. Researchers also examined the Corpus Glossary at Corpus Christi College in Cambridge, an early English dictionary, along with other medieval texts from Britain and continental Europe.
In some manuscripts, several pages contained sheep pox virus DNA. Researchers said this could indicate that animals infected with the disease were used to produce the parchment.
The team compared the genetic material recovered from the manuscripts with older DNA samples obtained from Bronze Age sheep teeth. Their analysis indicated that sheep pox has affected livestock for more than 3,700 years.
Sheep pox spreads quickly among animals and can infect a large proportion of a flock. The disease causes fever and skin lesions and can result in death. Outbreaks can also cause major financial losses through reduced milk production, damage to wool and hides, and restrictions on livestock trade.
There is no evidence that sheep pox infects humans.
The research, published in Science Advances, also provided insight into how the virus changed over time. Scientists found that the sheep pox virus genome remained relatively stable during the past several thousand years.
L’Hôte said the finding contrasts with the evolutionary history of some other pathogens, including smallpox. The stability of the sheep pox genome may indicate that important genetic changes occurred much earlier in the virus’s history and helped it adapt to sheep.
Researchers said the work could encourage scientists to examine other archives and libraries for genetic traces of historic animal diseases. Ancient DNA preserved in manuscripts could offer a new source of information about outbreaks that affected livestock and societies long before modern disease surveillance existed.
Health
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Health
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