Health
Raising Awareness of Haemochromatosis: The ‘Celtic Curse’ That Affects Millions
Haemochromatosis, a genetic condition that causes the body to store excessive amounts of iron, disproportionately affects people of Celtic heritage, including those from Ireland, Scotland, Wales, and Brittany. Despite its prevalence, awareness of the condition remains low, often leading to delayed diagnoses and increased health risks.
Iron is essential for producing haemoglobin, a protein in red blood cells responsible for oxygen transport. However, in individuals with haemochromatosis, iron accumulates in organs over time, potentially causing severe complications such as liver cirrhosis, liver cancer, and heart problems.
A Common but Underdiagnosed Condition
The condition often manifests through symptoms like fatigue, joint pain, and “brain fog,” which can appear as early as age 30 but are more common in men around 50 and women post-menopause. Diagnosis typically involves a blood test to detect mutations in the HFE gene, which regulates iron absorption. Individuals who inherit two faulty copies of the gene are at higher risk of developing the condition, while carriers with one faulty gene are less likely to experience symptoms.
Matt Skinner, 39, from Wales, shared his experience with haemochromatosis. “I had difficulty retaining information at work and felt constantly fatigued,” he said. Initially misdiagnosed with depression, Skinner’s condition was only identified after persistent medical consultations.
The Celtic Connection
Nicknamed the “Celtic Curse,” haemochromatosis is particularly prevalent among people of Irish descent. Studies by Haemochromatosis UK estimate that one in 10 people in Northern Ireland carries the gene mutation, compared to one in 113 in Scotland and one in 150 in England and Wales. Genetic traces of the condition have been found in human remains dating back to the Neolithic and Bronze Ages in Northern Ireland, underscoring its deep historical roots.
Despite its nickname, the reasons for the genetic mutation’s prominence in Celtic populations remain unclear.
Management and Treatment
While there is no cure for haemochromatosis, it can be effectively managed through early diagnosis and treatment. Options include venesection (similar to blood donation) to reduce iron levels and chelation therapy, which removes heavy metals from the blood. Early intervention minimizes the risk of organ damage and improves quality of life.
Edward Holland, 66, from England, has undergone 38 venesections since his diagnosis in 2023. “I feel as if I have more energy now,” he said, emphasizing the importance of awareness for earlier diagnosis and better outcomes.
Health organizations in Ireland and Scotland have ramped up efforts to encourage testing, but advocates like Skinner and Holland believe more public campaigns are needed. “If I’d been diagnosed earlier, I could be in maintenance now,” Skinner noted.
Haemochromatosis may be underdiagnosed, but with increased awareness and proactive testing, many more could benefit from early treatment and improved health outcomes.
Health
World Cup Emotion Can Strain the Heart, Cardiologists Warn Fans at Risk
As the World Cup begins, medical experts are cautioning football fans with underlying heart conditions that the emotional intensity of matches can place unexpected strain on the cardiovascular system.
Cardiologists say that the excitement, tension, and anxiety generated during high-stakes games can trigger physical reactions similar to intense exercise, raising heart rate, blood pressure, and stress hormones.
“Intense emotions, whether positive or negative, can act as ‘precipitating risk factors’ for cardiovascular events such as heart attack,” said Paola Santalucia, a cardiologist and board member of the European Heart Network.
She explained that moments of extreme excitement, such as a decisive penalty shootout or a last-minute goal, may pose risks for people already living with heart disease. Those with additional risk factors, including hypertension, obesity, or smoking habits, are also advised to be cautious during emotionally charged matches.
Research using wearable devices has shown that during major football events, some fans experience heart rates climbing as high as 150 beats per minute. That level is comparable to sprinting and reflects how strongly the body reacts to emotional stress.
A study examining supporters during the 2025 German Cup final found that even watching from home can significantly affect physiological responses. “They still had an increase in heart rate that compares to walking, even though they didn’t walk,” said Christian Deutscher, professor of sports economics at Bielefeld University and co-author of the study.
He noted that the most intense reactions often occur not during goals themselves, but during moments of uncertainty such as VAR checks, penalty shootouts, or shots striking the post. These unpredictable situations, he said, are what drive the strongest emotional and physical responses among fans.
Deutscher also pointed out that stadium spectators may experience even greater strain due to environmental factors such as heat and alcohol consumption.
However, experts emphasize that football itself is not inherently dangerous. Instead, it is the body’s natural response to excitement that can create temporary stress.
“The adrenergic stimulation is at its max: extreme high blood pressure, high heart rate, and adrenaline, cortisol, skyrocketing,” said Dan Atar, professor of cardiology at Oslo University Hospital. In rare cases, he added, this surge can contribute to the rupture of arterial plaque in vulnerable individuals, potentially leading to a heart attack.
Atar stressed that such events can occur in everyday situations as well, including physical exertion like shoveling snow. “It is in no way dangerous to watch a football game,” he said. “All this is physiologic. It’s not dangerous to be excited.”
Still, he acknowledged that combining emotional stress with alcohol, heat, and pre-existing conditions can increase risk for some viewers.
Doctors advise those at higher risk to continue prescribed medications, limit alcohol intake, avoid smoking, and watch for warning signs such as chest pain or irregular heartbeat.
“The key message is not to avoid enjoying the match, but to do so with moderation and awareness,” Santalucia said.
Health
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