Health
Ancient Ice Cave Bacteria in Romania Found Resistant to Modern Antibiotics
A strain of bacteria preserved for thousands of years in a Romanian ice cave has been found to resist multiple modern antibiotics, according to a new study published in Frontiers in Microbiology.
Researchers studying ice cores from Scărișoara Cave in western Romania discovered a cold-adapted bacterium known as Psychrobacter SC65A.3 beneath a 5,000-year-old layer of ice. Despite its ancient origin, the strain showed resistance to 10 antibiotics across eight different classes.
Scărișoara Cave contains one of the largest underground ice blocks in the world, measuring about 100,000 cubic metres and estimated to be around 13,000 years old. A research team drilled a 25-metre ice core from an area known as the Great Hall and analysed ice fragments to isolate bacterial strains. They sequenced the genomes to identify genes linked to survival in low temperatures and antimicrobial resistance.
Cristina Purcarea, a scientist at the Institute of Biology Bucharest of the Romanian Academy and lead author of the study, said the Psychrobacter SC65A.3 strain carries more than 100 genes associated with antibiotic resistance. She noted that the antibiotics to which the strain is resistant are widely used in both oral and injectable treatments for serious infections, including tuberculosis, colitis and urinary tract infections.
Bacteria are known to survive in extreme environments for extended periods, including beneath ancient ice sheets, in permafrost and in deep-sea or glacial ecosystems. Over time, they adapt to harsh conditions, developing mechanisms that allow persistence in cold and nutrient-limited settings.
The findings suggest that antibiotic resistance can evolve naturally in the environment, long before the development and widespread use of modern medicines. “Studying microbes such as Psychrobacter SC65A.3 retrieved from millennia-old cave ice deposits reveals how antibiotic resistance evolved naturally,” Purcarea said.
While antimicrobial resistance is a natural phenomenon, scientists warn that its spread has accelerated significantly due to prolonged and widespread antibiotic use in human and veterinary medicine.
Antimicrobial resistance is a growing global health concern. The European Centre for Disease Prevention and Control has estimated that more than 35,000 deaths occur annually in Europe due to drug-resistant infections. The number is expected to rise as populations age and resistant pathogens spread across borders. Overuse and misuse of antibiotics, along with gaps in infection control, have contributed to the problem.
According to the World Health Organization, one in six bacterial infections worldwide is now resistant to standard treatments.
Researchers say that understanding cold-adapted microbes is increasingly important, particularly as climate change affects frozen environments that cover roughly one-fifth of the Earth’s surface.
Health
Global Mental Health Cases Near 1.2 Billion as Anxiety and Depression Drive Sharp Worldwide Rise
A major global analysis has found that mental health conditions have surged to an estimated 1.2 billion people worldwide, driven largely by steep increases in anxiety and depression over the past three decades.
The findings, published in The Lancet as part of the Global Burden of Disease Study 2023, show that the number of people living with mental disorders has almost doubled since 1990, marking a 95% rise. Researchers say major depressive disorder and anxiety disorders have seen even sharper growth, increasing by 131% and 158% respectively, making them the most prevalent mental health conditions globally.
The report describes mental illnesses as widespread conditions that create long-term disability and significant human suffering. It also highlights broader consequences for economies and public services, including reduced productivity, lower workforce participation and increasing pressure on health and welfare systems.
Researchers estimate that in 2023 alone, around 620 million females and 552 million males were affected by mental health conditions. While the overall burden is rising across both sexes, the study points to notable differences in the types and prevalence of disorders.
Among women, depression and anxiety were the most commonly reported conditions, alongside higher rates of eating disorders such as anorexia nervosa and bulimia nervosa. The report links this disparity to a mix of biological, social and structural factors, including exposure to domestic violence, sexual abuse, gender inequality and reproductive health-related changes.
In contrast, neurodevelopmental and behavioural disorders, including attention deficit hyperactivity disorder (ADHD), conduct disorder and autism spectrum conditions, were more frequently diagnosed in men.
Teenagers aged 15 to 19 were identified as the group experiencing the highest mental health burden globally, raising concerns about early onset of conditions and insufficient preventive care for young people.
The study identifies several key risk factors associated with mental illness, including childhood sexual violence, bullying and intimate partner violence. These factors are strongly linked to conditions such as depression, schizophrenia, bipolar disorder and anxiety disorders. However, researchers note that such exposures have remained relatively stable over time and account for only a portion of the overall rise.
According to the authors, broader drivers are likely contributing to the increasing prevalence of mental disorders. These include genetic and biological influences, poverty, inequality, and the growing impact of global crises such as armed conflict, pandemics, natural disasters and climate-related stress.
While mental health conditions have long been a leading cause of disability worldwide, the report warns that the situation is worsening. At the same time, health systems have not expanded services at a pace matching demand.
The authors caution that the gap between rising need and limited access to care is becoming more pronounced, leaving millions without adequate treatment or support.
Health
Europe Records Sharp Rise in Sexually Transmitted Infections, ECDC Warns
Health
White House Rejects Report It Blocked Return of Ebola-Infected US Doctor
-
Entertainment2 years agoMeta Acquires Tilda Swinton VR Doc ‘Impulse: Playing With Reality’
-
Sports2 years agoChina’s Historic Olympic Victory Sparks National Pride Amid Controversy
-
Business2 years agoSaudi Arabia’s Model for Sustainable Aviation Practices
-
Business2 years agoRecent Developments in Small Business Taxes
-
Home Improvement1 year agoEffective Drain Cleaning: A Key to a Healthy Plumbing System
-
Politics2 years agoWho was Ebrahim Raisi and his status in Iranian Politics?
-
Sports2 years agoKeely Hodgkinson Wins Britain’s First Athletics Gold at Paris Olympics in 800m
-
Business2 years agoCarrectly: Revolutionizing Car Care in Chicago
