Health
Patchy European Laws Leave Thousands of Eggs and Embryos in Limbo
As fertility treatments become increasingly popular in Europe, inconsistent laws across the continent are leaving thousands of frozen eggs and embryos in legal and ethical uncertainty. Women are born with all the eggs they will ever have, and their reserves decline naturally after puberty, dropping more rapidly after 35 and reaching critically low levels by 40. At the same time, Europeans are having children later than ever, with the average maternal age now at 30.9 and fertility rates at a record low of 1.46 children per woman, influenced by higher living costs and job instability.
To address these challenges, more people are turning to in vitro fertilisation (IVF) and egg and embryo freezing, a practice known as social freezing. This allows individuals to preserve eggs at their peak quality for potential future use. The global market for egg freezing and embryo banking reached $5.41 billion (€4.55 billion) in 2024 and is projected to grow to around $25.63 billion (€22.1 billion) by 2034.
Saghar Kasiri, head of fertility services at Cryos, the world’s largest egg and sperm bank, described social egg freezing as “almost like an insurance policy.” She explained that patients store eggs in case they are not ready to conceive, but may later find natural pregnancy or change their life plans, leaving the frozen eggs unused. The same challenges apply to embryos, which are often produced in multiples during an IVF cycle. Modern vitrification can preserve embryos indefinitely, but their long-term storage raises moral and emotional questions, as well as practical ones about disposal or donation.
European countries vary widely in their approach to unused eggs and embryos. The United Kingdom allows unlimited embryo creation, transfers, and storage for up to 55 years, with options for donation, research, or destruction. In Poland, embryos cannot be destroyed, and donation to another couple becomes mandatory after 20 years. Italy requires unused embryos to remain frozen indefinitely and prohibits both research use and destruction, with over 10,000 abandoned embryos reported in 2025. Sweden, in contrast, mandates destruction after a 10-year storage limit.
Even in countries where donation or destruction is permitted, the process is often complex. In Spain, clinics must contact patients multiple times to confirm instructions for their embryos. If no response is received, the embryos fall under the clinic’s responsibility and may be donated, used in research, or destroyed. Spain has become Europe’s top destination for egg freezing, attracting international patients, which adds challenges to registry management and follow-up.
Kasiri noted that patients are often hesitant to donate embryos that contain their genetic material, particularly if both egg and sperm come from them, although donated embryos from donors are more likely to be shared with other families.
The rise in fertility preservation highlights the need for clear and harmonized regulations in Europe. Without coordinated laws, many eggs and embryos remain in legal limbo, raising ethical dilemmas and complicating reproductive planning for thousands of patients.
Health
Medieval Manuscripts Reveal Thousands-Year History of Deadly Sheep Virus
DNA recovered from medieval manuscripts has given scientists new clues about the long history of sheep pox, a highly contagious disease that has threatened livestock for thousands of years.
An international team led by researchers at University College Dublin discovered traces of sheep pox virus in parchment used for some of Europe’s historic manuscripts. The findings suggest that animal diseases may have left genetic records in old documents, providing scientists with another way to study how pathogens developed over time.
During the Middle Ages, parchment was commonly made from the treated skin of sheep, goats and cattle. Researchers extracted DNA from the animal skins used to produce centuries-old manuscripts and identified genetic material linked to the sheep pox virus.
The study involved geneticists, historians, virologists, protein chemists and conservation specialists. Louis L’Hôte, the study’s lead author, said the research showed that parchment could preserve DNA from animal pathogens and provide valuable evidence about infectious diseases in the past.
Among the manuscripts examined was the approximately 1,000-year-old York Gospels, considered one of the finest surviving illuminated manuscripts from the late Anglo-Saxon period. Researchers also examined the Corpus Glossary at Corpus Christi College in Cambridge, an early English dictionary, along with other medieval texts from Britain and continental Europe.
In some manuscripts, several pages contained sheep pox virus DNA. Researchers said this could indicate that animals infected with the disease were used to produce the parchment.
The team compared the genetic material recovered from the manuscripts with older DNA samples obtained from Bronze Age sheep teeth. Their analysis indicated that sheep pox has affected livestock for more than 3,700 years.
Sheep pox spreads quickly among animals and can infect a large proportion of a flock. The disease causes fever and skin lesions and can result in death. Outbreaks can also cause major financial losses through reduced milk production, damage to wool and hides, and restrictions on livestock trade.
There is no evidence that sheep pox infects humans.
The research, published in Science Advances, also provided insight into how the virus changed over time. Scientists found that the sheep pox virus genome remained relatively stable during the past several thousand years.
L’Hôte said the finding contrasts with the evolutionary history of some other pathogens, including smallpox. The stability of the sheep pox genome may indicate that important genetic changes occurred much earlier in the virus’s history and helped it adapt to sheep.
Researchers said the work could encourage scientists to examine other archives and libraries for genetic traces of historic animal diseases. Ancient DNA preserved in manuscripts could offer a new source of information about outbreaks that affected livestock and societies long before modern disease surveillance existed.
Health
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Health
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