Health
Polio Vaccination Campaign Concludes in Gaza Amid Conflict and Limited Access
Health workers in Gaza have completed a crucial polio vaccination campaign, aimed at protecting children under the age of 10 after the polio virus was detected in the region’s wastewater over three months ago. The campaign, led by the World Health Organization (WHO), successfully vaccinated approximately 557,000 children under 10 with their second dose of the polio vaccine, while over 448,000 children aged 2 to 10 received vitamin A supplements to boost their immune systems.
According to the WHO, the campaign achieved a 94% coverage rate within its target population. Vaccination efforts were especially successful in central and southern Gaza, where crowded living conditions in emergency shelters and tents have increased health risks. Despite these gains, between 7,000 and 10,000 children in northern Gaza remained unvaccinated due to “inaccessible” areas amidst ongoing conflict, leaving them vulnerable to polio infection.
“The lack of vaccination coverage in northern Gaza elevates the risk of poliovirus spreading not only within the Gaza Strip but also into neighboring regions,” the WHO stated, highlighting the importance of reaching a 90% vaccination rate to effectively halt transmission. Polio prevention typically requires two vaccine doses given approximately four weeks apart to achieve this level of community immunity.
The vaccination campaign faced significant challenges, beginning with the initial rollout in early September following a negotiated humanitarian pause. The second dose, scheduled for early October, was delayed due to escalated violence and tightened operational restrictions. The campaign finally resumed under another humanitarian pause, allowing health workers to operate within a restricted area. The campaign wrapped up on Tuesday.
The WHO emphasized that efforts to improve immunity and strengthen polio surveillance in Gaza would continue. “Routine immunization services at functional health facilities will be critical in sustaining immunity levels, along with enhanced disease surveillance to detect any new cases of poliovirus transmission,” the WHO stated.
The vaccination effort took place amid a severe health infrastructure crisis in Gaza. According to the latest WHO data, only 35% of Gaza’s primary health centers are partially operational, and 19 of Gaza’s 36 hospitals have been damaged or rendered unusable. This limited access to healthcare facilities poses an additional barrier to health initiatives in the area, including polio prevention and treatment.
The WHO and other international health organizations continue to advocate for uninterrupted humanitarian access to Gaza, stressing that further outbreaks of preventable diseases like polio could have devastating consequences in the region’s already fragile public health landscape.
Health
Medieval Manuscripts Reveal Thousands-Year History of Deadly Sheep Virus
DNA recovered from medieval manuscripts has given scientists new clues about the long history of sheep pox, a highly contagious disease that has threatened livestock for thousands of years.
An international team led by researchers at University College Dublin discovered traces of sheep pox virus in parchment used for some of Europe’s historic manuscripts. The findings suggest that animal diseases may have left genetic records in old documents, providing scientists with another way to study how pathogens developed over time.
During the Middle Ages, parchment was commonly made from the treated skin of sheep, goats and cattle. Researchers extracted DNA from the animal skins used to produce centuries-old manuscripts and identified genetic material linked to the sheep pox virus.
The study involved geneticists, historians, virologists, protein chemists and conservation specialists. Louis L’Hôte, the study’s lead author, said the research showed that parchment could preserve DNA from animal pathogens and provide valuable evidence about infectious diseases in the past.
Among the manuscripts examined was the approximately 1,000-year-old York Gospels, considered one of the finest surviving illuminated manuscripts from the late Anglo-Saxon period. Researchers also examined the Corpus Glossary at Corpus Christi College in Cambridge, an early English dictionary, along with other medieval texts from Britain and continental Europe.
In some manuscripts, several pages contained sheep pox virus DNA. Researchers said this could indicate that animals infected with the disease were used to produce the parchment.
The team compared the genetic material recovered from the manuscripts with older DNA samples obtained from Bronze Age sheep teeth. Their analysis indicated that sheep pox has affected livestock for more than 3,700 years.
Sheep pox spreads quickly among animals and can infect a large proportion of a flock. The disease causes fever and skin lesions and can result in death. Outbreaks can also cause major financial losses through reduced milk production, damage to wool and hides, and restrictions on livestock trade.
There is no evidence that sheep pox infects humans.
The research, published in Science Advances, also provided insight into how the virus changed over time. Scientists found that the sheep pox virus genome remained relatively stable during the past several thousand years.
L’Hôte said the finding contrasts with the evolutionary history of some other pathogens, including smallpox. The stability of the sheep pox genome may indicate that important genetic changes occurred much earlier in the virus’s history and helped it adapt to sheep.
Researchers said the work could encourage scientists to examine other archives and libraries for genetic traces of historic animal diseases. Ancient DNA preserved in manuscripts could offer a new source of information about outbreaks that affected livestock and societies long before modern disease surveillance existed.
Health
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Health
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