Health
EU Food Safety Agency Lowers Safe Fluoride Intake Amid Concerns Over Children’s Brain Development
The European Food Safety Authority (EFSA) has issued new guidance lowering the safe daily intake of fluoride, amid growing concerns that even low levels of exposure may impact children’s brain development.
In a comprehensive reassessment, EFSA said there is currently no strong evidence of serious health risks from fluoride at levels typically found in EU drinking water. However, the agency acknowledged that new scientific findings suggest possible links between fluoride exposure and lower IQ in children, prompting it to lower recommended safety thresholds.
Fluoride is a naturally occurring mineral widely known for its role in preventing tooth decay. While only a few European countries, including Ireland and parts of Spain, actively add fluoride to public water supplies, the substance is present in roughly 90% of toothpaste brands. Most EU drinking water contains fluoride concentrations below 0.3 milligrams per litre (mg/L), well within the bloc’s legal limit of 1.5 mg/L and the same maximum recommended by the World Health Organization (WHO).
Despite these low levels, EFSA’s new review—which analyzed over 20,000 scientific studies—raises fresh questions. Experts reviewed fluoride’s potential effects on the developing brain, bones, thyroid function, and dental health through common sources such as water, food, fluoridated salt, and dental care products.
“We estimated that, in general, with the current concentrations of fluoride in European drinking water, total fluoride exposure does not pose a health concern,” said EFSA toxicologist Susanne Hougaard Bennekou. However, she noted that children aged four to eight who regularly swallow toothpaste could face mild tooth discoloration, particularly in their developing molars. “This is unlikely to occur if children spit the toothpaste out properly after brushing,” she added.
In response to the findings, EFSA introduced new safe daily intake thresholds:
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1 mg/day for infants under one year
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1.6 mg/day for toddlers aged one to three
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2 mg/day for children aged four to eight
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3.3 mg/day for older children and adults, including pregnant women
These new recommendations aim to protect against potential risks to brain development, thyroid function, and bone health. While they currently serve as part of a consumer safety guideline, they may influence future revisions to EU regulations on fluoride in drinking water.
Still, experts say more research is needed. “There is evidence that we can’t ignore linking fluoride to possible effects on the developing nervous system of the foetus,” said Thorhallur Halldorsson, chair of EFSA’s working group on fluoride. “But the evidence is not yet strong enough to set a definitive threshold.”
The findings could renew debate across Europe on the use of fluoride in public health, especially as governments weigh the benefits of dental protection against emerging concerns over long-term neurological effects.
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Irregular Sleep Patterns Linked to Higher Anxiety Risk Among Teenagers
Teenagers who regularly change their sleeping patterns between weekdays and weekends may face a greater risk of anxiety, according to a new study from researchers at the University of Southampton in the United Kingdom.
The findings come as students return to school after the summer break, when many adolescents may have become accustomed to later nights and longer mornings. The shift back to early school schedules can create a mismatch between weekday and weekend sleep patterns, a phenomenon researchers describe as “social jet lag.”
A review of 12 studies involving more than 230,000 participants found that teenagers experiencing greater levels of social jet lag were more likely to report higher levels of anxiety. The relationship also appeared to work in the opposite direction, with higher anxiety associated with greater disruption to sleep schedules.
However, researchers stressed that the findings show an association rather than proving that irregular sleep directly causes anxiety.
The study highlights the importance of encouraging healthy and consistent sleeping habits as part of efforts to support adolescent mental health. Anxiety is already one of the most common mental health problems among young people.
The World Health Organization estimates that anxiety disorders affect about 4.4% of children aged 10 to 14 and 5.5% of those aged 15 to 19 worldwide. Such disorders involve persistent fear or nervousness that can be difficult to control.
Researchers say adolescence is a particularly important period for sleep because biological changes naturally alter young people’s body clocks.
Sarah Chellappa, a co-author of the study from the University of Southampton, said teenagers generally experience a shift toward later sleep during puberty.
“During puberty, the body’s internal clock usually shifts back by a few hours,” she said, meaning teenagers naturally become sleepy later and may need to wake later as well.
Early school starts can conflict with this biological change. Social activities, online communication and other demands can also reduce the amount of sleep teenagers get during the week.
Hannah Ravenhall, lead author of the study, said the issue should not be viewed solely as a matter of individual responsibility.
She said broader social systems can influence young people’s sleep and called for greater recognition of the biological changes that occur during adolescence.
The researchers suggested that schools could consider whether their start times adequately reflect teenagers’ changing sleep needs. Parents could also review evening routines, including rules around screen use.
Rather than simply encouraging teenagers to go to bed earlier, the researchers argue that more consistent schedules and changes to the environments in which young people live and study could help support better sleep and mental wellbeing.
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