Health
Artificial Sweeteners Linked to Faster Cognitive Decline, Study Finds
Artificial sweeteners found in diet sodas and low-calorie desserts may be linked to faster cognitive decline, according to new research published in the medical journal of the American Academy of Neurology.
The study, which tracked nearly 13,000 adults in Brazil over an average of eight years, found that people who consumed the highest amounts of artificial sweeteners experienced cognitive decline 62 per cent faster than those with the lowest intake. The decline was equivalent to around 1.6 years of ageing in terms of memory, language, and thinking skills.
“Low- and no-calorie sweeteners are often seen as a healthy alternative to sugar,” said lead author Claudia Kimie Suemoto, associate professor of geriatrics at the University of São Paulo. “However, our findings suggest certain sweeteners may have negative effects on brain health over time.”
The Study
Participants, who had an average age of 52 at the start, underwent repeated tests assessing cognitive function. They were divided into three groups based on sweetener consumption. The lowest-intake group consumed about 20 mg per day, while the highest group averaged 191 mg daily — roughly the amount of aspartame in a single can of diet soda.
Researchers examined several common sweeteners, including aspartame, saccharin, acesulfame-K, erythritol, xylitol, and sorbitol. All were linked to accelerated cognitive decline except for tagatose, which showed no significant effect.
The association was more pronounced among participants with diabetes, who often rely on sugar substitutes. However, no link was observed in participants over 60 years old, suggesting that mid-life consumption may have a greater impact on long-term brain health.
Broader Concerns
The findings add to a growing body of evidence questioning the long-term safety of artificial sweeteners. Previous research has connected non-sugar sweeteners to higher risks of type 2 diabetes and cardiovascular disease.
The International Agency for Research on Cancer has already classified aspartame as a possible carcinogen, though regulators have maintained that approved sweeteners remain safe within established limits.
Still, Suemoto stressed that the current study highlights associations rather than direct cause-and-effect. “More research is needed to determine exactly how artificial sweeteners may impact the brain,” she noted.
Regulation and Next Steps
In the European Union, all sugar alternatives must undergo safety evaluations before being sold, and their presence must be indicated on food and drink labels. The European Food Safety Authority (EFSA) is currently re-assessing the safety of sweeteners approved before 2009.
The study does have limitations, including reliance on participants’ self-reported diets and a focus on selected sweeteners. Nonetheless, experts say it underscores the need for closer scrutiny of products marketed as healthier sugar substitutes.
As consumers increasingly turn to low-calorie sweeteners in pursuit of healthier lifestyles, researchers warn that the long-term effects on brain health may not be as benign as once believed.
Health
World Cup Emotion Can Strain the Heart, Cardiologists Warn Fans at Risk
As the World Cup begins, medical experts are cautioning football fans with underlying heart conditions that the emotional intensity of matches can place unexpected strain on the cardiovascular system.
Cardiologists say that the excitement, tension, and anxiety generated during high-stakes games can trigger physical reactions similar to intense exercise, raising heart rate, blood pressure, and stress hormones.
“Intense emotions, whether positive or negative, can act as ‘precipitating risk factors’ for cardiovascular events such as heart attack,” said Paola Santalucia, a cardiologist and board member of the European Heart Network.
She explained that moments of extreme excitement, such as a decisive penalty shootout or a last-minute goal, may pose risks for people already living with heart disease. Those with additional risk factors, including hypertension, obesity, or smoking habits, are also advised to be cautious during emotionally charged matches.
Research using wearable devices has shown that during major football events, some fans experience heart rates climbing as high as 150 beats per minute. That level is comparable to sprinting and reflects how strongly the body reacts to emotional stress.
A study examining supporters during the 2025 German Cup final found that even watching from home can significantly affect physiological responses. “They still had an increase in heart rate that compares to walking, even though they didn’t walk,” said Christian Deutscher, professor of sports economics at Bielefeld University and co-author of the study.
He noted that the most intense reactions often occur not during goals themselves, but during moments of uncertainty such as VAR checks, penalty shootouts, or shots striking the post. These unpredictable situations, he said, are what drive the strongest emotional and physical responses among fans.
Deutscher also pointed out that stadium spectators may experience even greater strain due to environmental factors such as heat and alcohol consumption.
However, experts emphasize that football itself is not inherently dangerous. Instead, it is the body’s natural response to excitement that can create temporary stress.
“The adrenergic stimulation is at its max: extreme high blood pressure, high heart rate, and adrenaline, cortisol, skyrocketing,” said Dan Atar, professor of cardiology at Oslo University Hospital. In rare cases, he added, this surge can contribute to the rupture of arterial plaque in vulnerable individuals, potentially leading to a heart attack.
Atar stressed that such events can occur in everyday situations as well, including physical exertion like shoveling snow. “It is in no way dangerous to watch a football game,” he said. “All this is physiologic. It’s not dangerous to be excited.”
Still, he acknowledged that combining emotional stress with alcohol, heat, and pre-existing conditions can increase risk for some viewers.
Doctors advise those at higher risk to continue prescribed medications, limit alcohol intake, avoid smoking, and watch for warning signs such as chest pain or irregular heartbeat.
“The key message is not to avoid enjoying the match, but to do so with moderation and awareness,” Santalucia said.
Health
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Health
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