Health
UK Smokefree Generation Law Could Dramatically Reduce Youth Smoking, Study Finds
A new study suggests that the UK’s proposed smokefree generation law could lead to historically low levels of smoking among young people and deliver significant long-term health benefits. Researchers at the University of Nottingham projected that the policy could prevent tens of thousands of years of ill health, with an estimated 88,000 additional healthy life years gained by 2075 compared with no new legislation.
The proposed law, introduced by the UK government last year, aims to “break the cycle of addiction” by banning the sale of tobacco products to anyone born on or after 1 January 2009. Under the plan, the legal age for purchasing tobacco would increase by one year each year, effectively preventing an entire generation from ever legally buying cigarettes.
Using detailed modelling, the researchers examined how smoking prevalence among 12 to 30-year-olds in England could evolve under the new policy. The findings suggest that rates among this age group could fall below five percent by the late 2040s, decades earlier than projected without the law.
The study highlighted that the health gains would be particularly significant in disadvantaged communities, where smoking is more common. About 30 percent of the additional healthy life years are projected to occur in the most deprived 20 percent of neighbourhoods. Researchers noted, however, that men and people in lower-income communities may experience the benefits later unless support is targeted to these groups.
Lead author Nathan Davies, a researcher at the University of Nottingham’s School of Medicine, said the law could help stop young people from ever starting to smoke, accelerating progress toward a tobacco-free future. He added that the success of the policy would depend on effective enforcement, clear public communication, and accessible stop-smoking support, particularly in areas with high smoking rates.
Health organisations welcomed the research, emphasising that implementation would be critical. Alizée Froguel, prevention policy manager at Cancer Research UK, described the age-of-sale legislation as “a landmark step” in protecting future generations from the health and financial costs of smoking.
The study follows alarming statistics published by Wales’ public health agency, which reported that more than one in ten deaths among people aged over 35 between 2020 and 2022 were linked to smoking. Researchers believe that tailored communication campaigns and targeted investment in enforcement could help reduce health inequalities and ensure the policy’s benefits are shared more evenly across the population.
If passed, the UK would join a small group of countries with similar measures, including the Maldives, which bans tobacco sales to anyone born on or after 1 January 2007. New Zealand, which had proposed a similar plan, abandoned its initiative in 2023. The UK law is still under consideration in Parliament, with its introduction expected to position the country at the forefront of global tobacco control efforts.
Health
Medieval Manuscripts Reveal Thousands-Year History of Deadly Sheep Virus
DNA recovered from medieval manuscripts has given scientists new clues about the long history of sheep pox, a highly contagious disease that has threatened livestock for thousands of years.
An international team led by researchers at University College Dublin discovered traces of sheep pox virus in parchment used for some of Europe’s historic manuscripts. The findings suggest that animal diseases may have left genetic records in old documents, providing scientists with another way to study how pathogens developed over time.
During the Middle Ages, parchment was commonly made from the treated skin of sheep, goats and cattle. Researchers extracted DNA from the animal skins used to produce centuries-old manuscripts and identified genetic material linked to the sheep pox virus.
The study involved geneticists, historians, virologists, protein chemists and conservation specialists. Louis L’Hôte, the study’s lead author, said the research showed that parchment could preserve DNA from animal pathogens and provide valuable evidence about infectious diseases in the past.
Among the manuscripts examined was the approximately 1,000-year-old York Gospels, considered one of the finest surviving illuminated manuscripts from the late Anglo-Saxon period. Researchers also examined the Corpus Glossary at Corpus Christi College in Cambridge, an early English dictionary, along with other medieval texts from Britain and continental Europe.
In some manuscripts, several pages contained sheep pox virus DNA. Researchers said this could indicate that animals infected with the disease were used to produce the parchment.
The team compared the genetic material recovered from the manuscripts with older DNA samples obtained from Bronze Age sheep teeth. Their analysis indicated that sheep pox has affected livestock for more than 3,700 years.
Sheep pox spreads quickly among animals and can infect a large proportion of a flock. The disease causes fever and skin lesions and can result in death. Outbreaks can also cause major financial losses through reduced milk production, damage to wool and hides, and restrictions on livestock trade.
There is no evidence that sheep pox infects humans.
The research, published in Science Advances, also provided insight into how the virus changed over time. Scientists found that the sheep pox virus genome remained relatively stable during the past several thousand years.
L’Hôte said the finding contrasts with the evolutionary history of some other pathogens, including smallpox. The stability of the sheep pox genome may indicate that important genetic changes occurred much earlier in the virus’s history and helped it adapt to sheep.
Researchers said the work could encourage scientists to examine other archives and libraries for genetic traces of historic animal diseases. Ancient DNA preserved in manuscripts could offer a new source of information about outbreaks that affected livestock and societies long before modern disease surveillance existed.
Health
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Health
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