Health
Study Finds Intensive Blood Pressure Control Reduces Risk of Heart Attack and Stroke
Intensifying efforts to lower high blood pressure can significantly reduce the risk of heart attack, stroke, and related deaths, according to a new large-scale study published in The Lancet medical journal.
Hypertension, or high blood pressure, is one of the most common chronic health conditions globally, affecting an estimated 1.28 billion adults aged 30 to 79. If untreated, it can lead to serious complications including heart disease, stroke, and kidney failure. Standard treatment typically involves medication and lifestyle changes to lower systolic blood pressure—the top number in a reading—to around 140 millimetres of mercury (mmHg).
The new research suggests that lowering blood pressure even further, to below 120 or 130 mmHg, may deliver greater cardiovascular benefits. The study, led by a Chinese research team, analysed data from around 80,000 people across six clinical trials conducted in China, Canada, and the United States. Participants underwent varying treatment strategies, combining medication with lifestyle adjustments such as regular exercise, weight management, smoking cessation, and dietary improvements.
The analysis found that participants receiving intensive blood pressure control were less likely to suffer heart attacks, strokes, or cardiovascular-related deaths compared with those who followed standard treatment targets. “Our findings indicate a net benefit to intensive blood pressure management,” the authors noted, calling it the most comprehensive review to date of the approach’s health effects.
However, the study also highlighted potential drawbacks. Those in the intensive treatment group experienced higher rates of side effects, including dizziness, fainting, kidney issues, and irregular heart rhythms. These risks have fueled ongoing debate within the medical community about how aggressively to pursue lower blood pressure goals, particularly among older adults who may be more vulnerable to falls and complications.
The researchers stressed the importance of tailoring treatment to each patient. “The results underscore the need for individualised strategies to optimise outcomes while avoiding both overtreatment and undertreatment,” the study concluded.
Medical experts say the findings could influence future guidelines for hypertension management, as healthcare providers weigh the benefits of stricter control against the risks of side effects. With nearly half of global adults unaware they have high blood pressure, and only a fraction receiving effective treatment, the study reinforces the urgency of early diagnosis and careful monitoring.
As the debate continues, doctors are being urged to balance aggressive blood pressure control with patient safety, taking into account age, overall health, and individual risk factors.
Health
Global Mental Health Cases Near 1.2 Billion as Anxiety and Depression Drive Sharp Worldwide Rise
A major global analysis has found that mental health conditions have surged to an estimated 1.2 billion people worldwide, driven largely by steep increases in anxiety and depression over the past three decades.
The findings, published in The Lancet as part of the Global Burden of Disease Study 2023, show that the number of people living with mental disorders has almost doubled since 1990, marking a 95% rise. Researchers say major depressive disorder and anxiety disorders have seen even sharper growth, increasing by 131% and 158% respectively, making them the most prevalent mental health conditions globally.
The report describes mental illnesses as widespread conditions that create long-term disability and significant human suffering. It also highlights broader consequences for economies and public services, including reduced productivity, lower workforce participation and increasing pressure on health and welfare systems.
Researchers estimate that in 2023 alone, around 620 million females and 552 million males were affected by mental health conditions. While the overall burden is rising across both sexes, the study points to notable differences in the types and prevalence of disorders.
Among women, depression and anxiety were the most commonly reported conditions, alongside higher rates of eating disorders such as anorexia nervosa and bulimia nervosa. The report links this disparity to a mix of biological, social and structural factors, including exposure to domestic violence, sexual abuse, gender inequality and reproductive health-related changes.
In contrast, neurodevelopmental and behavioural disorders, including attention deficit hyperactivity disorder (ADHD), conduct disorder and autism spectrum conditions, were more frequently diagnosed in men.
Teenagers aged 15 to 19 were identified as the group experiencing the highest mental health burden globally, raising concerns about early onset of conditions and insufficient preventive care for young people.
The study identifies several key risk factors associated with mental illness, including childhood sexual violence, bullying and intimate partner violence. These factors are strongly linked to conditions such as depression, schizophrenia, bipolar disorder and anxiety disorders. However, researchers note that such exposures have remained relatively stable over time and account for only a portion of the overall rise.
According to the authors, broader drivers are likely contributing to the increasing prevalence of mental disorders. These include genetic and biological influences, poverty, inequality, and the growing impact of global crises such as armed conflict, pandemics, natural disasters and climate-related stress.
While mental health conditions have long been a leading cause of disability worldwide, the report warns that the situation is worsening. At the same time, health systems have not expanded services at a pace matching demand.
The authors caution that the gap between rising need and limited access to care is becoming more pronounced, leaving millions without adequate treatment or support.
Health
Europe Records Sharp Rise in Sexually Transmitted Infections, ECDC Warns
Health
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