Health
Study Finds US Doctors Prescribe ADHD Drugs Too Quickly for Young Children
A new study has found that many young children in the United States diagnosed with attention-deficit/hyperactivity disorder (ADHD) are being prescribed medication almost immediately, despite medical guidelines recommending behavioural therapy as the first step.
The analysis, published in JAMA Network Open, reviewed the cases of more than 9,700 children and revealed that 42.2% of four- and five-year-olds received ADHD medication within one month of diagnosis. By contrast, only 14.1% began drug treatment more than six months after diagnosis, the timeframe recommended by health experts.
Current US medical guidelines state that children aged four and five should undergo at least six months of behavioural therapy before starting on stimulants such as Ritalin or Concerta. These therapies aim to build skills and habits to help children manage daily challenges. Medication is considered a next step if behavioural treatment alone is not effective.
“This practice is concerning, because we know starting ADHD treatment with a behavioural approach is beneficial,” said Dr Yair Bannett, lead author of the study and assistant professor of paediatrics at Stanford University. “It has a big positive effect on the child as well as on the family.”
ADHD is one of the most common developmental disorders in children, affecting around 11.4% of Americans aged three to 17. Symptoms typically begin before age 12 and may include hyperactivity, restlessness, difficulty concentrating, and forgetfulness. Left untreated, ADHD can significantly affect academic performance and long-term outcomes into adulthood.
Experts note that while a combination of behavioural therapy and medication is often the most effective treatment, young children in particular should first be given non-drug interventions. However, access to behavioural therapy remains a challenge in many parts of the country, which may contribute to doctors prescribing medication sooner than recommended.
The study emphasised that safety concerns were not the primary issue. While ADHD medications are generally considered safe for young children, many families discontinue use due to side effects such as irritability, aggression, or heightened emotional reactions. “We never think of medication as the only solution for ADHD,” Bannett said, stressing that behavioural support is an essential component of treatment.
The researchers also highlighted limitations of the study, noting that it focused solely on the United States. ADHD prescribing patterns can vary significantly by region, with previous research suggesting children in North America are more likely to receive stimulant medications compared with their peers in Europe.
As the debate continues, the findings add weight to calls for expanding access to behavioural therapy, ensuring young children diagnosed with ADHD receive treatment in line with medical guidelines.
Health
Medieval Manuscripts Reveal Thousands-Year History of Deadly Sheep Virus
DNA recovered from medieval manuscripts has given scientists new clues about the long history of sheep pox, a highly contagious disease that has threatened livestock for thousands of years.
An international team led by researchers at University College Dublin discovered traces of sheep pox virus in parchment used for some of Europe’s historic manuscripts. The findings suggest that animal diseases may have left genetic records in old documents, providing scientists with another way to study how pathogens developed over time.
During the Middle Ages, parchment was commonly made from the treated skin of sheep, goats and cattle. Researchers extracted DNA from the animal skins used to produce centuries-old manuscripts and identified genetic material linked to the sheep pox virus.
The study involved geneticists, historians, virologists, protein chemists and conservation specialists. Louis L’Hôte, the study’s lead author, said the research showed that parchment could preserve DNA from animal pathogens and provide valuable evidence about infectious diseases in the past.
Among the manuscripts examined was the approximately 1,000-year-old York Gospels, considered one of the finest surviving illuminated manuscripts from the late Anglo-Saxon period. Researchers also examined the Corpus Glossary at Corpus Christi College in Cambridge, an early English dictionary, along with other medieval texts from Britain and continental Europe.
In some manuscripts, several pages contained sheep pox virus DNA. Researchers said this could indicate that animals infected with the disease were used to produce the parchment.
The team compared the genetic material recovered from the manuscripts with older DNA samples obtained from Bronze Age sheep teeth. Their analysis indicated that sheep pox has affected livestock for more than 3,700 years.
Sheep pox spreads quickly among animals and can infect a large proportion of a flock. The disease causes fever and skin lesions and can result in death. Outbreaks can also cause major financial losses through reduced milk production, damage to wool and hides, and restrictions on livestock trade.
There is no evidence that sheep pox infects humans.
The research, published in Science Advances, also provided insight into how the virus changed over time. Scientists found that the sheep pox virus genome remained relatively stable during the past several thousand years.
L’Hôte said the finding contrasts with the evolutionary history of some other pathogens, including smallpox. The stability of the sheep pox genome may indicate that important genetic changes occurred much earlier in the virus’s history and helped it adapt to sheep.
Researchers said the work could encourage scientists to examine other archives and libraries for genetic traces of historic animal diseases. Ancient DNA preserved in manuscripts could offer a new source of information about outbreaks that affected livestock and societies long before modern disease surveillance existed.
Health
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Health
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