Health
Spanish researchers develop corneal implants using discarded fish scales
Scientists in Granada have developed experimental corneal implants made from fish scales, a discovery that could help address the global shortage of donor corneas used in eye transplants.
The research, led by scientists at the University of Granada, focuses on transforming scales from commonly consumed fish such as Common carp into transparent and durable implants capable of repairing damaged corneas. Early laboratory tests and animal studies have produced encouraging results, according to the research team.
The project has been carried out by specialists from the university’s Department of Histology, who have spent several years studying fish scales that are normally discarded as waste in seafood markets.
Researchers say the structure of fish scales makes them a promising material for biomedical use. After processing and treatment, the scales can be converted into a biocompatible implant that is transparent and strong enough to function as a replacement for the cornea.
The cornea is the clear outer layer at the front of the eye and plays a key role in focusing vision. When the cornea becomes severely damaged due to injury or disease, the only effective treatment in many cases is a corneal transplant using donated tissue.
However, specialists say donor corneas are in short supply around the world. Many patients spend months or years on waiting lists, while others never receive a transplant due to the limited availability of suitable donor tissue.
Scientists at the University of Granada believe the new technique could offer an alternative solution if further testing confirms its effectiveness.
The study has been funded by the Instituto de Salud Carlos III, which operates under Spain’s Ministry of Science, Innovation and Universities. The research is part of project PI23/00335, which aims to explore new biomaterials for medical treatments.
The findings were presented in the presence of Manuel Reyes, manager of the Hospital Clínico San Cecilio in Granada. His participation highlights the growing interest from the medical community in the potential clinical use of the technology.
So far, the implants have successfully passed initial laboratory analysis and early tests in animals. These experiments were designed to confirm that the material is compatible with living tissue and capable of maintaining the structure required for a functioning cornea.
Despite the promising results, researchers caution that the technology is still in an early stage. Before the implants can be used in patients, the project must undergo extensive clinical trials in humans, a process that can take several years and requires strict regulatory approval.
For now, the study demonstrates that carp scales can be processed into a material that behaves similarly to a natural cornea at both structural and biological levels.
While the concept is not yet ready for use in operating rooms, scientists say the results represent an important step toward finding new ways to treat corneal damage in a field where donor shortages remain a major challenge.
Health
Global Mental Health Cases Near 1.2 Billion as Anxiety and Depression Drive Sharp Worldwide Rise
A major global analysis has found that mental health conditions have surged to an estimated 1.2 billion people worldwide, driven largely by steep increases in anxiety and depression over the past three decades.
The findings, published in The Lancet as part of the Global Burden of Disease Study 2023, show that the number of people living with mental disorders has almost doubled since 1990, marking a 95% rise. Researchers say major depressive disorder and anxiety disorders have seen even sharper growth, increasing by 131% and 158% respectively, making them the most prevalent mental health conditions globally.
The report describes mental illnesses as widespread conditions that create long-term disability and significant human suffering. It also highlights broader consequences for economies and public services, including reduced productivity, lower workforce participation and increasing pressure on health and welfare systems.
Researchers estimate that in 2023 alone, around 620 million females and 552 million males were affected by mental health conditions. While the overall burden is rising across both sexes, the study points to notable differences in the types and prevalence of disorders.
Among women, depression and anxiety were the most commonly reported conditions, alongside higher rates of eating disorders such as anorexia nervosa and bulimia nervosa. The report links this disparity to a mix of biological, social and structural factors, including exposure to domestic violence, sexual abuse, gender inequality and reproductive health-related changes.
In contrast, neurodevelopmental and behavioural disorders, including attention deficit hyperactivity disorder (ADHD), conduct disorder and autism spectrum conditions, were more frequently diagnosed in men.
Teenagers aged 15 to 19 were identified as the group experiencing the highest mental health burden globally, raising concerns about early onset of conditions and insufficient preventive care for young people.
The study identifies several key risk factors associated with mental illness, including childhood sexual violence, bullying and intimate partner violence. These factors are strongly linked to conditions such as depression, schizophrenia, bipolar disorder and anxiety disorders. However, researchers note that such exposures have remained relatively stable over time and account for only a portion of the overall rise.
According to the authors, broader drivers are likely contributing to the increasing prevalence of mental disorders. These include genetic and biological influences, poverty, inequality, and the growing impact of global crises such as armed conflict, pandemics, natural disasters and climate-related stress.
While mental health conditions have long been a leading cause of disability worldwide, the report warns that the situation is worsening. At the same time, health systems have not expanded services at a pace matching demand.
The authors caution that the gap between rising need and limited access to care is becoming more pronounced, leaving millions without adequate treatment or support.
Health
Europe Records Sharp Rise in Sexually Transmitted Infections, ECDC Warns
Health
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