Health
EU Food Safety Agency Lowers Safe Fluoride Intake Amid Concerns Over Children’s Brain Development
The European Food Safety Authority (EFSA) has issued new guidance lowering the safe daily intake of fluoride, amid growing concerns that even low levels of exposure may impact children’s brain development.
In a comprehensive reassessment, EFSA said there is currently no strong evidence of serious health risks from fluoride at levels typically found in EU drinking water. However, the agency acknowledged that new scientific findings suggest possible links between fluoride exposure and lower IQ in children, prompting it to lower recommended safety thresholds.
Fluoride is a naturally occurring mineral widely known for its role in preventing tooth decay. While only a few European countries, including Ireland and parts of Spain, actively add fluoride to public water supplies, the substance is present in roughly 90% of toothpaste brands. Most EU drinking water contains fluoride concentrations below 0.3 milligrams per litre (mg/L), well within the bloc’s legal limit of 1.5 mg/L and the same maximum recommended by the World Health Organization (WHO).
Despite these low levels, EFSA’s new review—which analyzed over 20,000 scientific studies—raises fresh questions. Experts reviewed fluoride’s potential effects on the developing brain, bones, thyroid function, and dental health through common sources such as water, food, fluoridated salt, and dental care products.
“We estimated that, in general, with the current concentrations of fluoride in European drinking water, total fluoride exposure does not pose a health concern,” said EFSA toxicologist Susanne Hougaard Bennekou. However, she noted that children aged four to eight who regularly swallow toothpaste could face mild tooth discoloration, particularly in their developing molars. “This is unlikely to occur if children spit the toothpaste out properly after brushing,” she added.
In response to the findings, EFSA introduced new safe daily intake thresholds:
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1 mg/day for infants under one year
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1.6 mg/day for toddlers aged one to three
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2 mg/day for children aged four to eight
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3.3 mg/day for older children and adults, including pregnant women
These new recommendations aim to protect against potential risks to brain development, thyroid function, and bone health. While they currently serve as part of a consumer safety guideline, they may influence future revisions to EU regulations on fluoride in drinking water.
Still, experts say more research is needed. “There is evidence that we can’t ignore linking fluoride to possible effects on the developing nervous system of the foetus,” said Thorhallur Halldorsson, chair of EFSA’s working group on fluoride. “But the evidence is not yet strong enough to set a definitive threshold.”
The findings could renew debate across Europe on the use of fluoride in public health, especially as governments weigh the benefits of dental protection against emerging concerns over long-term neurological effects.
Health
Global Mental Health Cases Near 1.2 Billion as Anxiety and Depression Drive Sharp Worldwide Rise
A major global analysis has found that mental health conditions have surged to an estimated 1.2 billion people worldwide, driven largely by steep increases in anxiety and depression over the past three decades.
The findings, published in The Lancet as part of the Global Burden of Disease Study 2023, show that the number of people living with mental disorders has almost doubled since 1990, marking a 95% rise. Researchers say major depressive disorder and anxiety disorders have seen even sharper growth, increasing by 131% and 158% respectively, making them the most prevalent mental health conditions globally.
The report describes mental illnesses as widespread conditions that create long-term disability and significant human suffering. It also highlights broader consequences for economies and public services, including reduced productivity, lower workforce participation and increasing pressure on health and welfare systems.
Researchers estimate that in 2023 alone, around 620 million females and 552 million males were affected by mental health conditions. While the overall burden is rising across both sexes, the study points to notable differences in the types and prevalence of disorders.
Among women, depression and anxiety were the most commonly reported conditions, alongside higher rates of eating disorders such as anorexia nervosa and bulimia nervosa. The report links this disparity to a mix of biological, social and structural factors, including exposure to domestic violence, sexual abuse, gender inequality and reproductive health-related changes.
In contrast, neurodevelopmental and behavioural disorders, including attention deficit hyperactivity disorder (ADHD), conduct disorder and autism spectrum conditions, were more frequently diagnosed in men.
Teenagers aged 15 to 19 were identified as the group experiencing the highest mental health burden globally, raising concerns about early onset of conditions and insufficient preventive care for young people.
The study identifies several key risk factors associated with mental illness, including childhood sexual violence, bullying and intimate partner violence. These factors are strongly linked to conditions such as depression, schizophrenia, bipolar disorder and anxiety disorders. However, researchers note that such exposures have remained relatively stable over time and account for only a portion of the overall rise.
According to the authors, broader drivers are likely contributing to the increasing prevalence of mental disorders. These include genetic and biological influences, poverty, inequality, and the growing impact of global crises such as armed conflict, pandemics, natural disasters and climate-related stress.
While mental health conditions have long been a leading cause of disability worldwide, the report warns that the situation is worsening. At the same time, health systems have not expanded services at a pace matching demand.
The authors caution that the gap between rising need and limited access to care is becoming more pronounced, leaving millions without adequate treatment or support.
Health
Europe Records Sharp Rise in Sexually Transmitted Infections, ECDC Warns
Health
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