Health
Study Links Eating Habits to Effectiveness of Popular Weight Loss Drugs
Doctors may need to consider their patients’ eating behaviours before prescribing blockbuster weight loss drugs, new research suggests.
A Japanese study has found that people who eat in response to emotions may not see the same benefits from widely used medications such as Ozempic, Wegovy, and Mounjaro as those who overeat when food looks or smells appealing. These drugs, known as glucagon-like peptide-1 (GLP-1) receptor agonists, mimic a hormone that reduces appetite and are increasingly prescribed for both diabetes and weight loss.
The year-long study, published in Frontiers in Clinical Diabetes and Healthcare, tracked 92 patients with diabetes who were taking GLP-1 drugs. Researchers from Gifu University and Kyoto University collected data on participants’ diets, blood markers, body composition, and weight changes. They also assessed patients’ relationships with food, focusing on three main eating patterns: eating in response to negative emotions, eating when food appeared appetising, and restricting diet for weight loss purposes.
Diverging Results Based on Eating Style
Most participants lost significant weight and showed improvements in cholesterol levels during the first year of treatment. However, outcomes varied depending on eating habits.
Those who tended to overeat because food looked appealing experienced the most consistent weight loss and improved blood sugar control over 12 months. In contrast, participants who relied on food to manage emotions were less likely to sustain benefits.
At the three-month mark, many patients showed greater control over their eating and were less likely to eat for emotional reasons or because of the appearance of food. But by the 12-month point, emotional and restrictive eating habits had re-emerged, suggesting that psychological factors may undermine long-term progress.
“Individuals with prominent emotional eating tendencies may require additional behavioural or psychological support,” said Dr Takehiro Kato, clinical lecturer at Gifu University and one of the study’s authors. “One possible explanation is that emotional eating is more strongly influenced by psychological factors which may not be directly addressed by GLP-1 receptor agonist therapy.”
Calls for More Research
While the findings highlight a potential link between eating behaviour and treatment outcomes, the researchers stressed that larger studies are needed before changes to clinical practice can be made.
“While our study suggests a potential association between external eating behaviour and treatment response to GLP-1 receptor agonists, these findings remain preliminary,” said Dr Daisuke Yabe, professor at Kyoto University and co-author of the study. “Further evidence is necessary before they can be implemented in clinical practice.”
The results underline the growing recognition that medication alone may not be sufficient for lasting weight loss, especially for patients who struggle with emotional eating. Experts say combining drug treatment with dietary guidance and psychological support may be the most effective path forward.
Health
World Cup Emotion Can Strain the Heart, Cardiologists Warn Fans at Risk
As the World Cup begins, medical experts are cautioning football fans with underlying heart conditions that the emotional intensity of matches can place unexpected strain on the cardiovascular system.
Cardiologists say that the excitement, tension, and anxiety generated during high-stakes games can trigger physical reactions similar to intense exercise, raising heart rate, blood pressure, and stress hormones.
“Intense emotions, whether positive or negative, can act as ‘precipitating risk factors’ for cardiovascular events such as heart attack,” said Paola Santalucia, a cardiologist and board member of the European Heart Network.
She explained that moments of extreme excitement, such as a decisive penalty shootout or a last-minute goal, may pose risks for people already living with heart disease. Those with additional risk factors, including hypertension, obesity, or smoking habits, are also advised to be cautious during emotionally charged matches.
Research using wearable devices has shown that during major football events, some fans experience heart rates climbing as high as 150 beats per minute. That level is comparable to sprinting and reflects how strongly the body reacts to emotional stress.
A study examining supporters during the 2025 German Cup final found that even watching from home can significantly affect physiological responses. “They still had an increase in heart rate that compares to walking, even though they didn’t walk,” said Christian Deutscher, professor of sports economics at Bielefeld University and co-author of the study.
He noted that the most intense reactions often occur not during goals themselves, but during moments of uncertainty such as VAR checks, penalty shootouts, or shots striking the post. These unpredictable situations, he said, are what drive the strongest emotional and physical responses among fans.
Deutscher also pointed out that stadium spectators may experience even greater strain due to environmental factors such as heat and alcohol consumption.
However, experts emphasize that football itself is not inherently dangerous. Instead, it is the body’s natural response to excitement that can create temporary stress.
“The adrenergic stimulation is at its max: extreme high blood pressure, high heart rate, and adrenaline, cortisol, skyrocketing,” said Dan Atar, professor of cardiology at Oslo University Hospital. In rare cases, he added, this surge can contribute to the rupture of arterial plaque in vulnerable individuals, potentially leading to a heart attack.
Atar stressed that such events can occur in everyday situations as well, including physical exertion like shoveling snow. “It is in no way dangerous to watch a football game,” he said. “All this is physiologic. It’s not dangerous to be excited.”
Still, he acknowledged that combining emotional stress with alcohol, heat, and pre-existing conditions can increase risk for some viewers.
Doctors advise those at higher risk to continue prescribed medications, limit alcohol intake, avoid smoking, and watch for warning signs such as chest pain or irregular heartbeat.
“The key message is not to avoid enjoying the match, but to do so with moderation and awareness,” Santalucia said.
Health
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Health
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