Health
Study Finds Deep, Long-Lasting Grief Can Raise Risk of Death by Nearly 90% Over a Decade
New research suggests that intense, long-term grief can significantly increase the risk of death, lending weight to the idea that it may be possible to die of a “broken heart” — even years after losing a loved one.
A decade-long Danish study has found that people experiencing the most persistent and severe grief after the death of a partner, parent, or close relative were 88% more likely to die within 10 years compared to those with the least intense symptoms.
The findings, published in Frontiers in Public Health, are based on a study of over 1,700 adults, primarily women, with an average age of 62. Participants were grouped into five categories based on the severity and duration of their grief. Those in the highest grief trajectory were found to have significantly worse health outcomes over the long term.
“These results suggest that grief can be much more than just emotional suffering — it can have serious implications for physical health and longevity,” said Mette Kjærgaard Nielsen, a postdoctoral researcher at Aarhus University and one of the study’s authors.
The research showed that people in the high-grief group were also far more likely to be using antidepressant medications or receiving psychological therapy more than three years after their loss. However, by the seven-year mark, the differences in mental health support between groups began to level off.
While the exact link between prolonged grief and early death remains unclear, Nielsen noted that individuals in the high-grief category often had lower education levels and were already using mental health medications before their loved ones died. This, she said, may indicate underlying psychological vulnerabilities that made them more susceptible to intense and lasting bereavement distress.
The study’s relatively small sample size — with just 107 participants in the high-grief group — means further research is needed to confirm the findings. Still, the results align with previous studies connecting grief to increased risks of cardiovascular disease, mental health problems, and suicide.
One known condition, takotsubo cardiomyopathy, or “broken heart syndrome,” is often triggered by extreme emotional stress. It mimics heart attack symptoms and can lead to temporary heart failure. Women are more likely to develop the condition, but men have a higher fatality rate, according to research published in the Journal of the American Heart Association.
Earlier studies have also shown that widowed individuals face elevated risks of death from heart disease, suicide, and even digestive and respiratory issues in the years following their loss.
Nielsen said the latest findings could help medical professionals better identify bereaved patients at higher risk. “This knowledge enables GPs and mental health professionals to offer early, tailored interventions and support,” she said, “potentially preventing further health deterioration after such a profound loss.”
Health
Medieval Manuscripts Reveal Thousands-Year History of Deadly Sheep Virus
DNA recovered from medieval manuscripts has given scientists new clues about the long history of sheep pox, a highly contagious disease that has threatened livestock for thousands of years.
An international team led by researchers at University College Dublin discovered traces of sheep pox virus in parchment used for some of Europe’s historic manuscripts. The findings suggest that animal diseases may have left genetic records in old documents, providing scientists with another way to study how pathogens developed over time.
During the Middle Ages, parchment was commonly made from the treated skin of sheep, goats and cattle. Researchers extracted DNA from the animal skins used to produce centuries-old manuscripts and identified genetic material linked to the sheep pox virus.
The study involved geneticists, historians, virologists, protein chemists and conservation specialists. Louis L’Hôte, the study’s lead author, said the research showed that parchment could preserve DNA from animal pathogens and provide valuable evidence about infectious diseases in the past.
Among the manuscripts examined was the approximately 1,000-year-old York Gospels, considered one of the finest surviving illuminated manuscripts from the late Anglo-Saxon period. Researchers also examined the Corpus Glossary at Corpus Christi College in Cambridge, an early English dictionary, along with other medieval texts from Britain and continental Europe.
In some manuscripts, several pages contained sheep pox virus DNA. Researchers said this could indicate that animals infected with the disease were used to produce the parchment.
The team compared the genetic material recovered from the manuscripts with older DNA samples obtained from Bronze Age sheep teeth. Their analysis indicated that sheep pox has affected livestock for more than 3,700 years.
Sheep pox spreads quickly among animals and can infect a large proportion of a flock. The disease causes fever and skin lesions and can result in death. Outbreaks can also cause major financial losses through reduced milk production, damage to wool and hides, and restrictions on livestock trade.
There is no evidence that sheep pox infects humans.
The research, published in Science Advances, also provided insight into how the virus changed over time. Scientists found that the sheep pox virus genome remained relatively stable during the past several thousand years.
L’Hôte said the finding contrasts with the evolutionary history of some other pathogens, including smallpox. The stability of the sheep pox genome may indicate that important genetic changes occurred much earlier in the virus’s history and helped it adapt to sheep.
Researchers said the work could encourage scientists to examine other archives and libraries for genetic traces of historic animal diseases. Ancient DNA preserved in manuscripts could offer a new source of information about outbreaks that affected livestock and societies long before modern disease surveillance existed.
Health
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Health
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