Health
Germany’s Growing Dependence on Chinese Pharmaceuticals Sparks Supply Concerns
Germany’s reliance on Chinese-made medicines has deepened significantly, with new data showing that China supplied more than twice the volume of pharmaceuticals to Germany in 2024 than it imported from Europe’s largest economy. According to figures from the German government, Germany sold more than 15 million tonnes of pharmaceutical products to China last year, while imports from China reached over 33 million tonnes — underscoring the extent of the dependency between the two markets.
China has become indispensable to Germany’s healthcare system, particularly for essential drug components. A report by the pharmaceutical association Pro Generika e.V. found that 76 percent of all active ingredients used in antibiotics imported to Germany now originate from China. Even medicines produced in India or the United States often rely on Chinese raw materials.
The diabetes drug Metformin illustrates this global interdependence. Of the 22 key manufacturers worldwide, 15 are based in India and two in China, while 80 percent of the compound dicyandiamide — essential for producing Metformin — comes from China. German pharmaceutical firms, pressured by discount agreements with health insurers, have been forced to source cheaper materials abroad to remain competitive.
Experts warn that this cost-driven strategy has left Europe vulnerable. “Cheap production abroad was the result of a ‘cheap is cool’ mentality,” said Michael Müller, professor of pharmaceutical and medicinal chemistry at the University of Freiburg. He cautioned that bringing production back to Germany would be prohibitively expensive and constrained by a shortage of skilled workers. “We can’t produce the required raw materials ourselves. We are clearly dependent on China,” he said.
The consequences are already visible. The Federal Union of German Associations of Pharmacists reported that roughly 500 prescription drugs were difficult to obtain in 2024, with shortages hitting antibiotics for children and medications for asthma and ADHD particularly hard. “Germany used to be the pharmacy of the world. Now the pharmacy of the world is in China or India,” said Thomas Preis, the union’s president. “If factories there have production problems, this is immediately reflected in supply here.”
Economists have also voiced concern that China could leverage its pharmaceutical dominance for political gain, similar to how it restricted exports of rare earth minerals during trade tensions with the United States. While some experts believe Germany would pay higher prices to secure medicines in a crisis, others argue that long-term resilience requires innovation and investment in new drug development.
“The global network is not an enemy but an opportunity — if we use it wisely,” Müller said, calling for Germany to focus on developing advanced manufacturing technologies and pioneering new treatments rather than competing on low-cost production.
Health
Medieval Manuscripts Reveal Thousands-Year History of Deadly Sheep Virus
DNA recovered from medieval manuscripts has given scientists new clues about the long history of sheep pox, a highly contagious disease that has threatened livestock for thousands of years.
An international team led by researchers at University College Dublin discovered traces of sheep pox virus in parchment used for some of Europe’s historic manuscripts. The findings suggest that animal diseases may have left genetic records in old documents, providing scientists with another way to study how pathogens developed over time.
During the Middle Ages, parchment was commonly made from the treated skin of sheep, goats and cattle. Researchers extracted DNA from the animal skins used to produce centuries-old manuscripts and identified genetic material linked to the sheep pox virus.
The study involved geneticists, historians, virologists, protein chemists and conservation specialists. Louis L’Hôte, the study’s lead author, said the research showed that parchment could preserve DNA from animal pathogens and provide valuable evidence about infectious diseases in the past.
Among the manuscripts examined was the approximately 1,000-year-old York Gospels, considered one of the finest surviving illuminated manuscripts from the late Anglo-Saxon period. Researchers also examined the Corpus Glossary at Corpus Christi College in Cambridge, an early English dictionary, along with other medieval texts from Britain and continental Europe.
In some manuscripts, several pages contained sheep pox virus DNA. Researchers said this could indicate that animals infected with the disease were used to produce the parchment.
The team compared the genetic material recovered from the manuscripts with older DNA samples obtained from Bronze Age sheep teeth. Their analysis indicated that sheep pox has affected livestock for more than 3,700 years.
Sheep pox spreads quickly among animals and can infect a large proportion of a flock. The disease causes fever and skin lesions and can result in death. Outbreaks can also cause major financial losses through reduced milk production, damage to wool and hides, and restrictions on livestock trade.
There is no evidence that sheep pox infects humans.
The research, published in Science Advances, also provided insight into how the virus changed over time. Scientists found that the sheep pox virus genome remained relatively stable during the past several thousand years.
L’Hôte said the finding contrasts with the evolutionary history of some other pathogens, including smallpox. The stability of the sheep pox genome may indicate that important genetic changes occurred much earlier in the virus’s history and helped it adapt to sheep.
Researchers said the work could encourage scientists to examine other archives and libraries for genetic traces of historic animal diseases. Ancient DNA preserved in manuscripts could offer a new source of information about outbreaks that affected livestock and societies long before modern disease surveillance existed.
Health
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Health
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