Health
Experts Weigh in on Dry January and the Health Risks of Alcohol Consumption
As the new year begins, many are considering the “Dry January” challenge, which involves abstaining from alcohol for the month. Experts highlight that reducing alcohol consumption is a key step toward improving health, debunking previous beliefs about the benefits of moderate drinking.
Dr. Timothy Naimi, director of the Canadian Institute for Substance Use Research at the University of Victoria, emphasized the risks associated with alcohol. “Drinking less is a great way to be healthier,” he said, adding that alcohol consumption is linked to several cancers, including colon, liver, breast, mouth, and throat cancers.
Alcohol metabolizes into acetaldehyde, a substance that can damage cells and hinder their repair processes, creating conditions for cancer development. Thousands of deaths in the U.S. could be prevented annually if people adhered to dietary guidelines that recommend men limit themselves to two drinks per day and women to one.
U.S. Surgeon General Dr. Vivek Murthy recently called for updating health warning labels on alcoholic beverages to include cancer risks, a proposal that would require Congressional approval. “As you consider whether or how much to drink, keep in mind that less is better when it comes to cancer risk,” Murthy wrote on social media platform X.
Reevaluating the “Moderate Drinking” Myth
The notion that moderate drinking benefits heart health stems from flawed studies that compared drinkers to non-drinkers without accounting for key variables such as education, income, and access to healthcare. Once these factors are adjusted, the supposed benefits largely disappear, Dr. Naimi explained.
Another issue is the age demographic studied. Most research focused on older adults who survived middle age without developing alcohol-related problems, creating a skewed perception of benefits for moderate drinkers. Nearly half of alcohol-related deaths occur in individuals under 50, highlighting the dangers of drinking at younger ages.
Genetic studies further challenge the benefits of alcohol. Research comparing individuals with a gene variant that makes drinking unpleasant to those without it found that people with the variant, who tend to drink little or none, have a lower risk of heart disease.
Global Shift Toward Drinking Less
Countries like the United Kingdom, France, and Australia have recently updated their alcohol guidelines, recommending lower consumption levels based on growing evidence linking alcohol to over 200 health conditions. Starting in 2026, Ireland will require cancer warning labels on alcoholic beverages.
“The scientific consensus has shifted due to the overwhelming evidence linking alcohol to cancers, cardiovascular diseases, and injuries,” said Carina Ferreira-Borges of the World Health Organization.
While the U.S. did not adopt stricter alcohol guidelines in 2020, experts like Dr. Naimi stress the importance of moderation. “The simple message supported by evidence is that, if you drink, less is better when it comes to health,” he said.
Health
Medieval Manuscripts Reveal Thousands-Year History of Deadly Sheep Virus
DNA recovered from medieval manuscripts has given scientists new clues about the long history of sheep pox, a highly contagious disease that has threatened livestock for thousands of years.
An international team led by researchers at University College Dublin discovered traces of sheep pox virus in parchment used for some of Europe’s historic manuscripts. The findings suggest that animal diseases may have left genetic records in old documents, providing scientists with another way to study how pathogens developed over time.
During the Middle Ages, parchment was commonly made from the treated skin of sheep, goats and cattle. Researchers extracted DNA from the animal skins used to produce centuries-old manuscripts and identified genetic material linked to the sheep pox virus.
The study involved geneticists, historians, virologists, protein chemists and conservation specialists. Louis L’Hôte, the study’s lead author, said the research showed that parchment could preserve DNA from animal pathogens and provide valuable evidence about infectious diseases in the past.
Among the manuscripts examined was the approximately 1,000-year-old York Gospels, considered one of the finest surviving illuminated manuscripts from the late Anglo-Saxon period. Researchers also examined the Corpus Glossary at Corpus Christi College in Cambridge, an early English dictionary, along with other medieval texts from Britain and continental Europe.
In some manuscripts, several pages contained sheep pox virus DNA. Researchers said this could indicate that animals infected with the disease were used to produce the parchment.
The team compared the genetic material recovered from the manuscripts with older DNA samples obtained from Bronze Age sheep teeth. Their analysis indicated that sheep pox has affected livestock for more than 3,700 years.
Sheep pox spreads quickly among animals and can infect a large proportion of a flock. The disease causes fever and skin lesions and can result in death. Outbreaks can also cause major financial losses through reduced milk production, damage to wool and hides, and restrictions on livestock trade.
There is no evidence that sheep pox infects humans.
The research, published in Science Advances, also provided insight into how the virus changed over time. Scientists found that the sheep pox virus genome remained relatively stable during the past several thousand years.
L’Hôte said the finding contrasts with the evolutionary history of some other pathogens, including smallpox. The stability of the sheep pox genome may indicate that important genetic changes occurred much earlier in the virus’s history and helped it adapt to sheep.
Researchers said the work could encourage scientists to examine other archives and libraries for genetic traces of historic animal diseases. Ancient DNA preserved in manuscripts could offer a new source of information about outbreaks that affected livestock and societies long before modern disease surveillance existed.
Health
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