Health
Europe Braces for Potentially Severe Flu Season Amid Low Vaccination Rates
Public health experts across Europe are warning that this year’s influenza season could be more severe than usual, as vaccination rates remain low and early signs from Asia and the southern hemisphere suggest a stronger wave of infections.
According to the European Centre for Disease Prevention and Control (ECDC), flu activity across the EU and surrounding countries remains “low but increasing,” as expected for mid-October. However, officials fear that a harsh winter and sluggish immunisation rates could create the conditions for widespread outbreaks in the months ahead.
“Europe’s flu season usually runs from November to May, but patterns have become less predictable since the COVID-19 pandemic,” said Colin Russell, professor at Amsterdam University Medical Center and chair of the European Scientific Working Group on Influenza (ESWI). He noted that last year’s flu season was unusually large following a shorter, milder one in 2023-24.
ECDC data shows that 11 European countries are already reporting sporadic flu activity, with the United Kingdom seeing early rises in infections, particularly among children. “It’s the time of year when everything starts,” said Dr Anna Odone, director of the School of Public Health at the University of Pavia in Italy.
Experts say the severity of this year’s flu season will depend on three key factors: how many vulnerable people there are, which flu strains dominate, and the environment. A long, cold winter could encourage indoor gatherings, making it easier for the virus to spread.
Health authorities are closely watching for outbreaks in schools, elderly care facilities, and prisons — areas where people are in close contact — to gauge when the season officially begins. Last year, influenza A (H1 and H3) and influenza B/Victoria were the dominant strains across Europe.
Clues from abroad suggest potential trouble. Australia and New Zealand recently saw a surge in the H3N2 strain toward the end of winter, while Japan declared a nationwide flu epidemic more than a month earlier than usual. Still, experts caution it’s too soon to know which strains will prevail in Europe. “We’re in wait-and-see mode right now,” Russell said.
While influenza rarely causes serious illness in healthy adults, it remains a significant public health concern, causing an estimated 27,600 deaths across the EU annually. Vaccination remains the most effective protection, but uptake has fallen sharply in many countries.
The EU target for flu vaccination coverage is 75%, yet most countries remain below 50%. Only Denmark (76%), Ireland (75%), Portugal (71%), and Sweden (68%) met or approached the target last season.
“Immunisation has social and political connotations,” Odone said. “It’s not easy to reach the high coverage levels needed to control influenza.”
The ECDC urged national governments to rebuild public trust in vaccines, improve access, and emphasise timely vaccination — especially for high-risk groups such as the elderly, pregnant women, children under five, and healthcare workers.
Russell advised people not to wait until flu cases surge: “If you’re not vaccinated yet, now is the time to do it.”
Health
Medieval Manuscripts Reveal Thousands-Year History of Deadly Sheep Virus
DNA recovered from medieval manuscripts has given scientists new clues about the long history of sheep pox, a highly contagious disease that has threatened livestock for thousands of years.
An international team led by researchers at University College Dublin discovered traces of sheep pox virus in parchment used for some of Europe’s historic manuscripts. The findings suggest that animal diseases may have left genetic records in old documents, providing scientists with another way to study how pathogens developed over time.
During the Middle Ages, parchment was commonly made from the treated skin of sheep, goats and cattle. Researchers extracted DNA from the animal skins used to produce centuries-old manuscripts and identified genetic material linked to the sheep pox virus.
The study involved geneticists, historians, virologists, protein chemists and conservation specialists. Louis L’Hôte, the study’s lead author, said the research showed that parchment could preserve DNA from animal pathogens and provide valuable evidence about infectious diseases in the past.
Among the manuscripts examined was the approximately 1,000-year-old York Gospels, considered one of the finest surviving illuminated manuscripts from the late Anglo-Saxon period. Researchers also examined the Corpus Glossary at Corpus Christi College in Cambridge, an early English dictionary, along with other medieval texts from Britain and continental Europe.
In some manuscripts, several pages contained sheep pox virus DNA. Researchers said this could indicate that animals infected with the disease were used to produce the parchment.
The team compared the genetic material recovered from the manuscripts with older DNA samples obtained from Bronze Age sheep teeth. Their analysis indicated that sheep pox has affected livestock for more than 3,700 years.
Sheep pox spreads quickly among animals and can infect a large proportion of a flock. The disease causes fever and skin lesions and can result in death. Outbreaks can also cause major financial losses through reduced milk production, damage to wool and hides, and restrictions on livestock trade.
There is no evidence that sheep pox infects humans.
The research, published in Science Advances, also provided insight into how the virus changed over time. Scientists found that the sheep pox virus genome remained relatively stable during the past several thousand years.
L’Hôte said the finding contrasts with the evolutionary history of some other pathogens, including smallpox. The stability of the sheep pox genome may indicate that important genetic changes occurred much earlier in the virus’s history and helped it adapt to sheep.
Researchers said the work could encourage scientists to examine other archives and libraries for genetic traces of historic animal diseases. Ancient DNA preserved in manuscripts could offer a new source of information about outbreaks that affected livestock and societies long before modern disease surveillance existed.
Health
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