Health
Cannabis and Cocaine Lead EU Drug Use, But Synthetic Drugs Pose Growing Risks
Cannabis and cocaine remain the most commonly used drugs in the European Union (EU), but emerging synthetic substances are raising new public health concerns, according to a recent report by the European Commission and the Organisation for Economic Co-operation and Development (OECD).
Drug Use Patterns Across the EU
The report highlights that nearly one in three Europeans has tried illegal drugs at some point, with 15% of young adults using cannabis and 2.5% using cocaine in 2024. However, drug consumption patterns vary significantly between countries.
- Cannabis use is highest in the Czech Republic, Italy, France, and Spain, while the lowest rates are found in Malta, Turkey, and Hungary.
- Cocaine use is most prevalent in the Netherlands, Spain, and Ireland, but significantly lower in Turkey, Portugal, Poland, and Hungary.
Despite variations in drug policies across Europe, experts say tougher laws do not necessarily impact drug availability, especially among young people.
“The major penalties impact only the people who use the substance once or fewer times in a year, so not the real [heavy] users,” said Sabrina Molinaro, an epidemiologist at Italy’s National Research Council and coordinator of the European School Survey Project on Alcohol and Other Drugs.
Her research has monitored 16-year-olds’ drug use in Europe since the 1990s, revealing consistent generational trends. Notably, while teenage boys historically used cannabis more than girls, that gender gap is narrowing, and in some countries, girls now surpass boys in cannabis use.
The Rise of Synthetic and Harder Drugs
While cannabis and cocaine remain the dominant substances, other illegal drugs—such as MDMA (ecstasy), heroin, opioids, psychedelics, and synthetic drugs—are posing increasing threats.
Synthetic drugs, including lab-made cannabinoids and stimulants, are particularly concerning due to their unpredictable chemical makeup and low-quality production conditions.
“They are so dangerous because you don’t know what you are taking,” Molinaro warned, adding that some synthetic drugs are produced in poorly regulated labs, leading to potential contamination.
The EU Drugs Agency (EUDA) reported that in 2022, authorities dismantled hundreds of synthetic drug labs across the continent. The following year, seven new synthetic opioid substances—known for their high potency—were detected through the agency’s early warning system.
Health Risks and Policy Challenges
Regular drug use in the EU is associated with cardiovascular diseases, mental health issues, accidents, and infectious diseases like HIV, particularly among people using injectable substances.
Molinaro stressed that the rising presence of synthetic opioids poses serious health risks to the adult population. Given their potency, even small doses can be lethal, increasing the urgency for rapid detection and intervention.
As Europe faces an influx of new and harder-to-regulate drugs, public health experts warn that governments must adapt quickly to prevent widespread harm.
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Health
Medieval Manuscripts Reveal Thousands-Year History of Deadly Sheep Virus
DNA recovered from medieval manuscripts has given scientists new clues about the long history of sheep pox, a highly contagious disease that has threatened livestock for thousands of years.
An international team led by researchers at University College Dublin discovered traces of sheep pox virus in parchment used for some of Europe’s historic manuscripts. The findings suggest that animal diseases may have left genetic records in old documents, providing scientists with another way to study how pathogens developed over time.
During the Middle Ages, parchment was commonly made from the treated skin of sheep, goats and cattle. Researchers extracted DNA from the animal skins used to produce centuries-old manuscripts and identified genetic material linked to the sheep pox virus.
The study involved geneticists, historians, virologists, protein chemists and conservation specialists. Louis L’Hôte, the study’s lead author, said the research showed that parchment could preserve DNA from animal pathogens and provide valuable evidence about infectious diseases in the past.
Among the manuscripts examined was the approximately 1,000-year-old York Gospels, considered one of the finest surviving illuminated manuscripts from the late Anglo-Saxon period. Researchers also examined the Corpus Glossary at Corpus Christi College in Cambridge, an early English dictionary, along with other medieval texts from Britain and continental Europe.
In some manuscripts, several pages contained sheep pox virus DNA. Researchers said this could indicate that animals infected with the disease were used to produce the parchment.
The team compared the genetic material recovered from the manuscripts with older DNA samples obtained from Bronze Age sheep teeth. Their analysis indicated that sheep pox has affected livestock for more than 3,700 years.
Sheep pox spreads quickly among animals and can infect a large proportion of a flock. The disease causes fever and skin lesions and can result in death. Outbreaks can also cause major financial losses through reduced milk production, damage to wool and hides, and restrictions on livestock trade.
There is no evidence that sheep pox infects humans.
The research, published in Science Advances, also provided insight into how the virus changed over time. Scientists found that the sheep pox virus genome remained relatively stable during the past several thousand years.
L’Hôte said the finding contrasts with the evolutionary history of some other pathogens, including smallpox. The stability of the sheep pox genome may indicate that important genetic changes occurred much earlier in the virus’s history and helped it adapt to sheep.
Researchers said the work could encourage scientists to examine other archives and libraries for genetic traces of historic animal diseases. Ancient DNA preserved in manuscripts could offer a new source of information about outbreaks that affected livestock and societies long before modern disease surveillance existed.
Health
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