Health
Drug-Resistant Infections Projected to Surge Across Europe as Population Ages
Rates of bloodstream infections caused by antibiotic-resistant bacteria are expected to rise sharply across Europe in the coming years, with older adults likely to be the hardest hit, according to a new study published in PLOS Medicine.
The research found that as Europe’s population continues to age, infections caused by so-called “superbugs” will become increasingly common and dangerous. Antimicrobial resistance (AMR) occurs when bacteria evolve to the point where antibiotics are no longer effective, leading to harder-to-treat infections. Globally, these resistant pathogens already kill around one million people each year.
The study projected that rates of drug-resistant infections will climb steadily through 2030, with significant variations depending on the country, gender, age group, and specific bacteria-antibiotic combinations. Overall, the increase in bloodstream infections is expected to range from 22.2 percent for Streptococcus pneumoniae infections among women to 61.5 percent for Klebsiella pneumoniae infections among men.
The analysis also found that men are likely to experience higher infection rates than women for six of the eight bacterial types examined. The uptick will have a greater impact on older adults, particularly those aged 74 and above, who are more vulnerable to severe complications such as sepsis when bloodstream infections occur.
“Our study shows that the future burden of drug-resistant infections won’t be uniform,” said Gwenan Knight, senior author of the study and co-director of the Antimicrobial Resistance Centre at the London School of Hygiene & Tropical Medicine. “Age and sex are still rarely considered in antimicrobial resistance projections, yet they make a real difference to who is most affected.”
To conduct the analysis, researchers examined data from over 12.8 million blood tests across 29 European countries between 2010 and 2019. Using these data, they developed models to forecast trends in bloodstream infections through 2050.
Knight said that understanding which populations face the greatest risk will help scientists and policymakers design more effective prevention and treatment strategies. Tailored interventions could include improving infection control measures in hospitals and care homes, investing in new antibiotics, and promoting responsible antibiotic use.
However, the study cautioned that meeting international targets to curb antibiotic resistance will be difficult. The World Health Organization and other global health bodies have set a goal of reducing antibiotic-resistant infections by 10 percent by 2030. According to the research, this target is likely achievable for only about two-thirds of the bacteria-antibiotic combinations studied.
Given the growing threat, Knight noted that holding infection rates steady could itself be a public health success. “Simply preventing further rises in resistant bloodstream infections would already be a major public health achievement,” she said.
Health
Global Mental Health Cases Near 1.2 Billion as Anxiety and Depression Drive Sharp Worldwide Rise
A major global analysis has found that mental health conditions have surged to an estimated 1.2 billion people worldwide, driven largely by steep increases in anxiety and depression over the past three decades.
The findings, published in The Lancet as part of the Global Burden of Disease Study 2023, show that the number of people living with mental disorders has almost doubled since 1990, marking a 95% rise. Researchers say major depressive disorder and anxiety disorders have seen even sharper growth, increasing by 131% and 158% respectively, making them the most prevalent mental health conditions globally.
The report describes mental illnesses as widespread conditions that create long-term disability and significant human suffering. It also highlights broader consequences for economies and public services, including reduced productivity, lower workforce participation and increasing pressure on health and welfare systems.
Researchers estimate that in 2023 alone, around 620 million females and 552 million males were affected by mental health conditions. While the overall burden is rising across both sexes, the study points to notable differences in the types and prevalence of disorders.
Among women, depression and anxiety were the most commonly reported conditions, alongside higher rates of eating disorders such as anorexia nervosa and bulimia nervosa. The report links this disparity to a mix of biological, social and structural factors, including exposure to domestic violence, sexual abuse, gender inequality and reproductive health-related changes.
In contrast, neurodevelopmental and behavioural disorders, including attention deficit hyperactivity disorder (ADHD), conduct disorder and autism spectrum conditions, were more frequently diagnosed in men.
Teenagers aged 15 to 19 were identified as the group experiencing the highest mental health burden globally, raising concerns about early onset of conditions and insufficient preventive care for young people.
The study identifies several key risk factors associated with mental illness, including childhood sexual violence, bullying and intimate partner violence. These factors are strongly linked to conditions such as depression, schizophrenia, bipolar disorder and anxiety disorders. However, researchers note that such exposures have remained relatively stable over time and account for only a portion of the overall rise.
According to the authors, broader drivers are likely contributing to the increasing prevalence of mental disorders. These include genetic and biological influences, poverty, inequality, and the growing impact of global crises such as armed conflict, pandemics, natural disasters and climate-related stress.
While mental health conditions have long been a leading cause of disability worldwide, the report warns that the situation is worsening. At the same time, health systems have not expanded services at a pace matching demand.
The authors caution that the gap between rising need and limited access to care is becoming more pronounced, leaving millions without adequate treatment or support.
Health
Europe Records Sharp Rise in Sexually Transmitted Infections, ECDC Warns
Health
White House Rejects Report It Blocked Return of Ebola-Infected US Doctor
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