Health
Portugal Limits Prescriptions for Popular Diabetes and Weight Loss Drugs Amid Misuse Concerns
The Portuguese government has moved to curb the misuse of certain high-demand diabetes and weight loss drugs, as well as glucose monitoring devices, by restricting which doctors can prescribe them.
Effective Friday, only specialists in endocrinology and nutrition, internal medicine, paediatrics, and general and family medicine will be authorised to prescribe glucagon-like peptide-1 (GLP-1) receptor agonists — including Ozempic, Wegovy, and Mounjaro — and glucose sensors. These injectable medications, used to treat type 2 diabetes and obesity, have gained worldwide popularity for their weight loss effects, creating shortages and driving demand beyond approved medical use.
Ozempic, produced by Danish pharmaceutical firm Novo Nordisk, is officially authorised in Portugal solely for treating type 2 diabetes. However, its appetite-suppressing effects have made it a sought-after weight loss aid, leading to market shortages. Wegovy, also from Novo Nordisk, and Eli Lilly’s Mounjaro are approved for both diabetes and obesity treatment. According to official data, Portuguese consumers spent approximately €21 million on these drugs in the first four months of 2025 alone.
Glucose sensors, designed to help diabetics monitor blood sugar levels, have also been in short supply. Reports indicate they have been prescribed by non-specialist doctors and are being used by dieters, athletes, social media influencers, and even for monitoring animals.
The Ministry of Health, which announced the regulation in April, cited “recent reports of improper access to and use of these technologies, which have jeopardised their availability to those who actually need them.” It said the measure is intended to “regulate and correct these distortions, promoting effective and adequate access to these essential health tools.”
João Raposo, president of the Portuguese Society of Diabetology (SPD), welcomed the move but expressed doubt over its effectiveness, suggesting that prescriptions outside the approved specialties may already be limited. While not opposed to the drugs being used for obesity treatment, Raposo warned of “anomalous prescriptions and a lack of monitoring” among non-diabetic users.
“Health cannot be subject to the laws of the market,” he stressed, noting the temptation such drugs pose for those “desperately looking for solutions.”
GLP-1 medicines are reimbursed by the Portuguese state at 90 per cent, while glucose sensors can be subsidised up to 85 per cent. However, shortages have also fuelled a black market, raising concerns about counterfeit products.
The government hopes the new prescribing rules will ensure that supplies remain available for patients who medically require them — but experts caution that enforcement and oversight will be key to its success.
Health
Medieval Manuscripts Reveal Thousands-Year History of Deadly Sheep Virus
DNA recovered from medieval manuscripts has given scientists new clues about the long history of sheep pox, a highly contagious disease that has threatened livestock for thousands of years.
An international team led by researchers at University College Dublin discovered traces of sheep pox virus in parchment used for some of Europe’s historic manuscripts. The findings suggest that animal diseases may have left genetic records in old documents, providing scientists with another way to study how pathogens developed over time.
During the Middle Ages, parchment was commonly made from the treated skin of sheep, goats and cattle. Researchers extracted DNA from the animal skins used to produce centuries-old manuscripts and identified genetic material linked to the sheep pox virus.
The study involved geneticists, historians, virologists, protein chemists and conservation specialists. Louis L’Hôte, the study’s lead author, said the research showed that parchment could preserve DNA from animal pathogens and provide valuable evidence about infectious diseases in the past.
Among the manuscripts examined was the approximately 1,000-year-old York Gospels, considered one of the finest surviving illuminated manuscripts from the late Anglo-Saxon period. Researchers also examined the Corpus Glossary at Corpus Christi College in Cambridge, an early English dictionary, along with other medieval texts from Britain and continental Europe.
In some manuscripts, several pages contained sheep pox virus DNA. Researchers said this could indicate that animals infected with the disease were used to produce the parchment.
The team compared the genetic material recovered from the manuscripts with older DNA samples obtained from Bronze Age sheep teeth. Their analysis indicated that sheep pox has affected livestock for more than 3,700 years.
Sheep pox spreads quickly among animals and can infect a large proportion of a flock. The disease causes fever and skin lesions and can result in death. Outbreaks can also cause major financial losses through reduced milk production, damage to wool and hides, and restrictions on livestock trade.
There is no evidence that sheep pox infects humans.
The research, published in Science Advances, also provided insight into how the virus changed over time. Scientists found that the sheep pox virus genome remained relatively stable during the past several thousand years.
L’Hôte said the finding contrasts with the evolutionary history of some other pathogens, including smallpox. The stability of the sheep pox genome may indicate that important genetic changes occurred much earlier in the virus’s history and helped it adapt to sheep.
Researchers said the work could encourage scientists to examine other archives and libraries for genetic traces of historic animal diseases. Ancient DNA preserved in manuscripts could offer a new source of information about outbreaks that affected livestock and societies long before modern disease surveillance existed.
Health
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Health
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