Business
Pharmaceutical Firms Scale Back UK Investments Amid Drug Pricing Disputes
Multinational drugmakers are pausing or pulling back investments in the United Kingdom, citing concerns over uncompetitive drug pricing and strained relations with the government. The slowdown comes as Britain seeks to position itself as a hub for life sciences, a sector the government has long promoted as central to its post-Brexit economic strategy.
Eli Lilly, AstraZeneca, and Merck are among the companies that have recently scaled back or halted projects in the UK. Earlier this month, AstraZeneca suspended a planned £200 million expansion of its Cambridge research site, following the cancellation of a vaccine project in Liverpool. Merck, known in Europe as MSD, said it would relocate its London research operations to the United States. Meanwhile, Eli Lilly has paused its £279 million London Gateway Lab, saying it was awaiting “more clarity around the UK life sciences environment.”
The moves follow sharp criticism from Eli Lilly’s chief executive Dave Ricks, who last week told the Financial Times that Britain was “probably the worst country in Europe” for drug pricing. His remarks have further highlighted growing friction between the pharmaceutical industry and the government.
Richard Torbett, chief executive of the Association of the British Pharmaceutical Industry (ABPI), urged ministers to act. “We have a long and proud history of researching and manufacturing medicines in this country,” he said. “This is why we urge the government to improve how this country values and attracts future life sciences manufacturing.”
The UK spends a smaller share of its health budget on medicines than most developed nations — around 9% compared with 14–20% elsewhere. Much of this is due to the NHS’s heavy use of generic drugs and the role of the National Institute for Health and Care Excellence (NICE), which determines whether branded medicines are cost-effective. In addition, the Voluntary Scheme for Branded Medicines Pricing, Access and Growth (VPAG) caps NHS spending on branded medicines, requiring firms to pay back revenue when expenditure exceeds agreed limits. Companies argue the rebates have become unsustainable.
Adding to the pressure, new U.S. trade policies are reshaping the global market. President Donald Trump recently announced 100% tariffs on branded drug imports unless firms build plants in the U.S., alongside a “most favoured nation” pricing policy that could ripple across Europe. With the U.S. accounting for roughly 70% of global pharma profits, analysts say many companies are prioritising American operations over European ones.
Experts note that higher UK drug prices are not necessarily the solution. Irene Papanicolas, director at the Brown University School of Public Health, argued that if pharma firms retreat, “the bigger impact is on the economy and jobs” rather than patient access to medicines. Beth Woods, senior research fellow at the University of York, added: “Our research supports more stringent price regulation in the UK. More investment could fund screening programmes, hip replacements, or staffing increases.”
Analysts say that beyond pricing, the UK must strengthen its tax incentives, infrastructure, and research funding to remain attractive. Without decisive action, they warn, Britain risks losing ground in the global competition for pharmaceutical investment.
Business
Shein Shares Slide on Hong Kong Debut as Tariffs Hit Fast-Fashion Business
Shein shares fell sharply on their Hong Kong trading debut on Tuesday, dropping as much as 10% before recovering some of the losses, as the fast-fashion company faces rising tariffs and shipping costs that have put pressure on its profits.
The listing marks the end of a lengthy effort by Shein to enter public markets. The company had previously considered listings in New York and London but faced regulatory scrutiny over its Chinese supply chain and business practices. It eventually turned to Hong Kong for its initial public offering.
Shein priced its shares at HK$48.56 each and raised about $1.7 billion (€1.46 billion), making the offering one of Hong Kong’s largest share sales of the year. The company opened its IPO for investors on August 24 before setting the final share price on August 31. Trading began on Tuesday after the exchange completed its approval process.
Shares initially dropped below HK$44 before narrowing their losses.
“Shein’s Hong Kong listing marks a new starting point,” Chief Financial Officer Leigh Gui said during the company’s listing ceremony.
The company has built its global business around producing inexpensive clothing quickly and shipping orders from China to customers in Western markets. That model is now facing higher costs as the US and European Union reduce or end tariff exemptions for low-value parcels from China.
Shein’s profits have been hit by the changing trade environment. The company reported a $99 million (€85 million) loss in the first quarter of the year, compared with a profit of $395 million (€340 million) a year earlier.
Higher shipping expenses have added to the pressure, making it harder for the company to maintain its low-price strategy. Tariff costs have also forced Shein to increase prices, potentially weakening one of its biggest attractions to consumers.
Shein was founded in China in 2012 and later moved its corporate headquarters to Singapore in 2021. Despite that move, its manufacturing network remains closely connected to Guangdong province, where the company developed its small-batch production system.
Founder Sky Xu has described Guangdong as the company’s roots and the starting point of its growth.
The company has also faced regulatory challenges in Europe. In February, the EU opened an investigation into Shein over concerns involving allegedly illegal products, including accusations related to child sexual abuse material.
Shein’s Hong Kong debut values the company at roughly $27 billion (€23.2 billion), far below its peak private-market valuation.
The listing nevertheless gives Hong Kong’s stock market a major boost. The exchange has attracted more than $40 billion (€34.4 billion) through IPOs so far this year, as companies continue to seek access to international investors through the city’s financial markets.
Business
Eurozone Inflation Jumps to 3.3% as Energy Costs Surge
Eurozone inflation rose sharply in August, reaching 3.3 percent as energy prices climbed at their fastest pace in months amid higher oil and gas costs and disruption to shipping through the Strait of Hormuz.
The annual inflation rate increased from 2.9 percent in July, according to a flash estimate from Eurostat, the European Union’s statistical office. The rise puts inflation well above the European Central Bank’s 2 percent target and could strengthen expectations of another interest rate increase.
Energy prices were the main driver behind the acceleration. They rose 14.3 percent in the year to August, up from an annual increase of 10.3 percent in July. On a monthly basis, energy prices increased 2.9 percent, contributing significantly to the overall rise in consumer prices.
Services inflation, which is closely monitored by the ECB because it tends to be more persistent, eased to 3 percent in August from 3.3 percent in July.
Core inflation also slowed slightly. The measure, which excludes energy, food, alcohol and tobacco, fell from 2.5 percent to 2.4 percent. Food, alcohol and tobacco prices increased 1.2 percent from a year earlier, unchanged from July.
The figures indicate that higher energy costs have not yet translated into a broad increase in underlying price pressures. However, economists expect elevated gas and food prices to continue affecting inflation in the months ahead.
Leo Barincou, senior economist at Oxford Economics, said the increase was driven by a rebound in fuel prices following the renewed closure of the Strait of Hormuz. He said underlying price pressures remained contained because services inflation had eased, but inflation was likely to stay above the ECB’s target into next year.
Inflation varied considerably across the eurozone. Lithuania recorded the highest rate among countries included in the flash estimate, at 5.8 percent, while Estonia had the lowest at 1.3 percent.
Among the bloc’s largest economies, inflation stood at 2.7 percent in France and 2.9 percent in Germany, both below the eurozone average. France nevertheless saw a notable increase from 2.4 percent in July. Spain recorded inflation of 4.5 percent, while Italy reached 3.2 percent.
Markets are expecting the ECB to raise interest rates by 0.25 percentage points at its September 10 meeting as policymakers respond to renewed price pressures.
Barincou said inflation was accelerating and the ECB was highly likely to raise rates next week, but warned against assuming that another increase would immediately follow, given that underlying inflation pressures remain relatively contained.
The latest figures leave policymakers facing a difficult balance between controlling inflation and avoiding excessive pressure on economic activity.
Business
White House Details Major Venezuela Oil Deal as US Secures Stake in Reserves
The White House has released details of a major agreement involving Venezuela’s oil industry, identifying the private company at the centre of the deal and outlining Washington’s financial and operational interests in more than 65 billion barrels of crude reserves.
The Trump administration described the arrangement as the largest oil deal in history. A fact sheet released Monday night named North American Blue Energy Partners, or NABEP, as the operator and provided details of the ownership structure and commitments involved.
Venezuela’s interim authorities have granted NABEP 100-year concessions covering 17 oil fields. The agreement was signed by US Secretary of State Marco Rubio and US Secretary of War Pete Hegseth.
The reserves covered by the agreement are significantly larger than America’s domestic oil reserves. The 65 billion barrels under the concessions compare with about 46 billion barrels across US territory.
Speaking in the Oval Office on Monday, President Donald Trump described the Venezuelan reserves as an enormous resource that had remained unused. He said the US would take the oil out and again claimed major American oil companies were interested in participating.
“We have Exxon going in, we have Chevron going in, we have our big oil companies going in,” Trump said.
Under the agreement, NABEP will provide the US Department of War’s Office of Strategic Capital with a 35 percent equity stake in its parent company. The White House said the stake could eventually be worth hundreds of billions of dollars without requiring money from US taxpayers.
The US State Department will also have the right to purchase 20 percent of production from all current and future NABEP fields at production cost. The oil is intended in part to replenish the US Strategic Petroleum Reserve. Washington will also have a right of first refusal on the remaining 80 percent of production.
The agreement gives the US a veto over board appointments, while a majority of directors must be US citizens. The contracts will also operate under US law and be subject to US courts.
NABEP has committed to investing as much as $100 billion in Venezuela’s oil infrastructure and is expected to pay about $200 billion in royalties and taxes over 25 years.
Many of the fields involved were previously operated by Russian or Chinese companies, a development the White House has presented as a renewed assertion of US influence in the region.
Questions remain over the deal, particularly among major oil companies. NABEP is controlled by Venezuelan businessman Alejandro Betancourt, who has faced investigations by US and European authorities over previous dealings with Venezuela’s government. He has never been charged and denies wrongdoing.
ExxonMobil and ConocoPhillips, which left Venezuela after assets were nationalised in 2007, have continued to call for strong legal protections before returning.
US lawmakers have also requested more information about the agreement, which was negotiated without congressional involvement.
Additional energy contracts are expected to be signed this week, potentially providing a clearer indication of whether major international oil companies are prepared to join the plan.
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