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Study Reveals Surprising Global Patterns in Loneliness Among Older Adults

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A major international study has uncovered significant differences in how loneliness affects older adults and those in midlife, depending on where they live. The findings challenge long-held assumptions that loneliness primarily affects the very old and very young, suggesting instead that geography, social systems, and life circumstances play key roles.

Researchers analyzed data from more than 64,000 people aged 50 to 90 across 29 countries, mostly in Europe, using a standardized loneliness scale that asked how often participants felt isolated, lacked companionship, or were left out.

The study, published in Aging & Mental Health, found that people generally become lonelier as they age. However, the extent of that loneliness varied significantly by country. In Bulgaria and Latvia, for example, older adults reported some of the steepest increases in loneliness with age, while countries like Denmark, Switzerland, and Austria reported the lowest loneliness levels overall.

Conversely, in the United States, the most pronounced loneliness was found not among the elderly but among people in midlife—making it the only country in the study where that was the case. A similar trend appeared in the Netherlands, though researchers noted data limitations there.

The study identified key factors linked to loneliness across all age groups, including unemployment, poor health, depression, and being unmarried. However, the impact of these factors varied between countries. In the U.S., for instance, being out of work in midlife was especially tied to feelings of isolation.

“Loneliness is not just a late-life issue,” said Esteban Calvo, senior author of the study and dean at Universidad Mayor in Chile. “Our findings suggest it’s influenced by a range of societal and personal factors, not just age.”

Experts say the study underscores the need for tailored, culturally sensitive approaches to addressing loneliness. “A one-size-fits-all approach will not solve this worldwide problem,” Calvo added.

The study did have limitations. Data were collected before the COVID-19 pandemic, and low response rates in some countries may affect how representative the results are. It also did not fully distinguish between different life circumstances—such as whether someone was widowed or had never married—making some findings harder to interpret.

Still, researchers say the implications are important. “Loneliness is a bit like hunger,” said Caterina Mauri, a senior researcher at the Free University of Brussels, who was not involved in the study. “It’s a signal to seek more connections, and when ignored, it can lead to serious mental and physical health consequences.”

With loneliness increasingly recognized as a global health concern, experts say more attention must be paid—not just to the elderly, but to people of all ages facing social disconnection.

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US Expands Measles Vaccination Guidance Amid Global Surge in Cases

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U.S. health officials have expanded their vaccination guidance for international travellers as measles cases rise sharply around the world, including in Europe and the United States.

The Centers for Disease Control and Prevention (CDC) now recommends that all international travellers be vaccinated against measles, regardless of their destination. Previously, the CDC’s focus was on countries experiencing known outbreaks, but this latest update reflects growing concern over transmission during travel itself.

“This change is significant,” said Ashley Darcy-Mahoney, a health researcher at George Washington University’s School of Nursing. “We’re seeing a shift from localised outbreaks to transmission in transit. Measles is now being spread not only in outbreak zones but also on airplanes and during international travel.”

The updated guidance urges U.S. travellers aged 1 year and older to receive two doses of the measles-mumps-rubella (MMR) vaccine before departing the country. Infants between 6 and 11 months old should receive an early dose, aligning with recommendations from the European Centre for Disease Prevention and Control (ECDC), which has also advised travellers to ensure they are fully vaccinated.

Measles is a highly contagious viral disease that spreads through coughing, sneezing, and close contact. Even brief exposure in confined spaces—such as airports or airplanes—can result in infection, particularly among unvaccinated individuals.

The CDC’s change comes amid a troubling global resurgence of measles. So far in 2025, more than 1,000 measles cases have been reported across the U.S., while the European Union has logged over 5,500 cases. Health officials have attributed many of the new infections to gaps in immunisation, often exacerbated by misinformation and pandemic-related disruptions to routine childhood vaccinations.

In the U.S., a recent outbreak in Colorado was traced back to an international flight that landed in Denver, underscoring the risks of in-flight transmission and the importance of proactive immunisation.

Measles was declared eliminated in the U.S. in 2000, but periodic outbreaks have occurred in recent years, often linked to unvaccinated travellers bringing the virus back from abroad.

Public health experts stress that maintaining high vaccination coverage is key to preventing further spread. The MMR vaccine is safe and highly effective, providing lifelong protection in most individuals after two doses.

“Given the rise in global travel and measles cases, the updated CDC guidance is a timely reminder that vaccination remains one of our strongest tools to protect public health,” Darcy-Mahoney said.

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Irish Hospital Leads Charge to Cut Nitrous Oxide Waste Amid Climate Concerns

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St John’s Hospital in Limerick has become one of the first medical facilities in Ireland to take decisive action against the environmental impact of nitrous oxide emissions by deactivating its central pipeline system for the gas, long used as an anaesthetic. The move is part of a growing effort in the healthcare sector to reduce its carbon footprint and curb avoidable waste.

Nitrous oxide, commonly known as laughing gas, has been used in hospitals for decades to relieve pain and anxiety during procedures. However, studies have shown that large volumes of the gas leak into the atmosphere due to outdated infrastructure, where it can remain for up to 120 years and contribute significantly to global warming.

Dr Hugh O’Callaghan, a consultant anaesthetist at St John’s, explained that while nitrous oxide remains safe and effective for clinical use, its delivery through centralised piping systems leads to “inevitable waste.” Instead, the hospital will now use portable canisters brought directly into operating rooms, a method that reduces gas leakage and emissions.

This initiative aligns with Ireland’s national plan to cut carbon emissions from anaesthetic gases by 50% by 2030. Other hospitals across the country are expected to follow St John’s lead in the coming months, according to the Health Service Executive (HSE).

Similar steps have already been taken in parts of the United Kingdom and the Netherlands. In England, hospitals that replaced central gas systems with mobile units saw a 55% drop in monthly nitrous oxide emissions, according to the NHS. In Manchester, the switch reportedly lowered the local health trust’s overall carbon footprint by up to 5%.

“It’s not about limiting clinical care—it’s about smarter, more sustainable delivery,” said Dr Cliff Shelton, a UK anaesthetist and co-chair of the environmental committee at the Association of Anaesthetists. The group has recommended decommissioning hospital nitrous oxide pipelines across the UK and Ireland by 2027.

Healthcare professionals increasingly acknowledge their sector’s role in climate change. Globally, the health sector accounts for about 4.4% of total emissions, with the European Union responsible for 248 million metric tons of carbon dioxide annually—trailing only the United States and China.

Although nitrous oxide and other anaesthetic gases contribute significantly to this footprint, experts stress that the bulk of emissions stem from the healthcare supply chain, including pharmaceuticals and medical equipment.

Still, efforts like those at St John’s Hospital are seen as important first steps. “When we looked into this, we found we were buying 100 times more nitrous oxide than we were actually using,” said Dr Shelton. “It’s a moral imperative to address that kind of waste.”

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Exercise Proven to Boost Survival and Reduce Recurrence in Colon Cancer Patients, Landmark Study Finds

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Regular physical activity could become a new standard in cancer care, following results from a major international study that found structured exercise programs significantly improve survival and reduce recurrence in colon cancer patients.

The findings, presented Sunday at the American Society of Clinical Oncology’s (ASCO) annual meeting in Chicago and published in the New England Journal of Medicine, offer the strongest evidence to date linking exercise to better cancer outcomes. Researchers from Canada, the UK, Australia, Israel, and the U.S. followed 889 patients who had completed chemotherapy for treatable colon cancer.

Participants were randomly divided into two groups: one received standard health education materials on fitness and nutrition, while the other was enrolled in a three-year coaching program. Those in the exercise group met with a coach every two weeks for a year and monthly for the following two years, receiving guidance and motivation to maintain regular physical activity.

After eight years of follow-up, patients in the exercise group experienced 28% fewer cancer recurrences and 37% fewer deaths from any cause compared to the control group.

“When we saw the results, we were just astounded,” said Dr. Christopher Booth, an oncologist at Kingston Health Sciences Centre in Ontario and a study co-author. “This is a remarkably affordable intervention that helps people feel better, live longer, and keep cancer at bay.”

Dr. Jeffrey Meyerhardt, one of the lead researchers, said this is the first randomized controlled trial to show a direct causal link between exercise and cancer recurrence prevention. Previous studies had only observed correlations.

“This is about as high a quality of evidence as you can get,” said Dr. Julie Gralow, ASCO’s chief medical officer. “I love this study because it confirms what many of us in oncology have believed for years, but couldn’t yet prove.”

While the benefits are clear, minor side effects were also reported — including muscle strains — highlighting the need for guided and gradual exercise routines. Still, the impact is seen as comparable to some cancer therapies, sparking calls for exercise programs to be integrated into cancer care and covered by insurance.

For participants like 62-year-old Terri Swain-Collins of Kingston, Ontario, the program proved life-changing. “It gave me something I could do to make myself feel better,” she said, adding that the regular check-ins kept her accountable and active.

Researchers are now analyzing blood samples collected during the study to better understand how exercise biologically influences cancer outcomes, including potential links to improved insulin processing and immune function.

With these findings, experts say cancer survivors now have a powerful, evidence-based reason to stay active — and a potential lifeline to long-term health.

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