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Raising Awareness of Haemochromatosis: The ‘Celtic Curse’ That Affects Millions

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Haemochromatosis, a genetic condition that causes the body to store excessive amounts of iron, disproportionately affects people of Celtic heritage, including those from Ireland, Scotland, Wales, and Brittany. Despite its prevalence, awareness of the condition remains low, often leading to delayed diagnoses and increased health risks.

Iron is essential for producing haemoglobin, a protein in red blood cells responsible for oxygen transport. However, in individuals with haemochromatosis, iron accumulates in organs over time, potentially causing severe complications such as liver cirrhosis, liver cancer, and heart problems.

A Common but Underdiagnosed Condition

The condition often manifests through symptoms like fatigue, joint pain, and “brain fog,” which can appear as early as age 30 but are more common in men around 50 and women post-menopause. Diagnosis typically involves a blood test to detect mutations in the HFE gene, which regulates iron absorption. Individuals who inherit two faulty copies of the gene are at higher risk of developing the condition, while carriers with one faulty gene are less likely to experience symptoms.

Matt Skinner, 39, from Wales, shared his experience with haemochromatosis. “I had difficulty retaining information at work and felt constantly fatigued,” he said. Initially misdiagnosed with depression, Skinner’s condition was only identified after persistent medical consultations.

The Celtic Connection

Nicknamed the “Celtic Curse,” haemochromatosis is particularly prevalent among people of Irish descent. Studies by Haemochromatosis UK estimate that one in 10 people in Northern Ireland carries the gene mutation, compared to one in 113 in Scotland and one in 150 in England and Wales. Genetic traces of the condition have been found in human remains dating back to the Neolithic and Bronze Ages in Northern Ireland, underscoring its deep historical roots.

Despite its nickname, the reasons for the genetic mutation’s prominence in Celtic populations remain unclear.

Management and Treatment

While there is no cure for haemochromatosis, it can be effectively managed through early diagnosis and treatment. Options include venesection (similar to blood donation) to reduce iron levels and chelation therapy, which removes heavy metals from the blood. Early intervention minimizes the risk of organ damage and improves quality of life.

Edward Holland, 66, from England, has undergone 38 venesections since his diagnosis in 2023. “I feel as if I have more energy now,” he said, emphasizing the importance of awareness for earlier diagnosis and better outcomes.

Health organizations in Ireland and Scotland have ramped up efforts to encourage testing, but advocates like Skinner and Holland believe more public campaigns are needed. “If I’d been diagnosed earlier, I could be in maintenance now,” Skinner noted.

Haemochromatosis may be underdiagnosed, but with increased awareness and proactive testing, many more could benefit from early treatment and improved health outcomes.

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Papua New Guinea Launches Emergency Polio Response After New Cases Detected

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Health authorities in Papua New Guinea have launched an urgent national vaccination campaign following the detection of two polio cases in children, marking the country’s first confirmed outbreak of the virus since 2018.

The Ministry of Health confirmed this week that poliovirus was found in two otherwise healthy children during routine screenings. Subsequent testing of sewage samples in Lae, the country’s second-largest city, verified that the virus is circulating in the community.

Health Minister Elias Kapavore described the situation as “serious but manageable” and urged swift action. “We’ve dealt with this before and know what works,” he said in a public statement, referring to a previous outbreak in 2018 that resulted in 26 cases of paralysis.

Although Papua New Guinea was declared polio-free in 2000, the recent cases underscore the country’s vulnerability due to persistently low vaccination rates among children. Polio, a highly contagious viral disease, primarily affects children under five and can lead to irreversible paralysis or death in severe cases. The disease has been largely eradicated globally, with only a few endemic regions remaining, such as Afghanistan and Pakistan.

The United Nations Children’s Fund (UNICEF) is working closely with the government to support the emergency vaccination drive. “While the focus right now is on stopping this outbreak, we must take this opportunity to boost routine immunisation to 90 per cent and protect children long-term,” said Dr Veera Mendonca, UNICEF’s representative in Papua New Guinea.

Mendonca emphasised that a long-term strategy to raise routine immunisation coverage is essential to prevent future outbreaks. UNICEF is also assisting in disease surveillance and public education efforts to raise awareness of the risks posed by polio and the importance of vaccination.

The outbreak response will target communities across the country, with particular focus on areas with the lowest immunisation coverage. Health officials are urging parents to ensure their children receive the polio vaccine, which remains the only effective way to prevent infection.

With a population of nearly 12 million and significant logistical challenges in remote areas, ensuring high vaccination coverage will be a complex task. However, authorities remain confident in their ability to contain the outbreak with coordinated action and international support.

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Healthy Diet May Delay Onset of Menstruation, Study Finds

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A healthy diet may help delay the onset of menstruation in young girls, potentially reducing their risk of several health issues later in life, according to new research published in the journal Human Reproduction.

The study, conducted by researchers at the Fred Hutchinson Cancer Center in the U.S., followed over 7,500 girls between the ages of 9 and 14 to explore the link between dietary habits and the timing of their first menstrual periods. Girls who adhered to the healthiest diets were found to be 16% less likely to experience early menstruation compared to those with the poorest dietary habits.

In contrast, girls who consumed the most inflammatory foods — such as processed meats, sugary drinks, and refined carbohydrates — were 15% more likely to begin menstruating at an earlier age. These results were independent of body size, reinforcing the impact of diet quality regardless of a child’s weight or height.

These findings demonstrate the importance of a healthy diet regardless of body size,” said Dr. Holly Harris, lead author of the study and associate professor at Fred Hutchinson Cancer Center. “This is particularly relevant as early menstruation has been associated with long-term health risks including obesity, type 2 diabetes, cardiovascular disease, and breast cancer.”

Typically, girls begin puberty between the ages of 8 and 13, with menstruation occurring roughly two years after breast development. However, a trend toward earlier onset of puberty has raised concerns among health professionals, especially given its links to chronic illnesses in adulthood.

While the study highlights a possible role for diet in influencing menstrual timing, some experts have cautioned against drawing firm conclusions. Dr. Imogen Roger, a research fellow at Brighton and Sussex Medical School, noted that the data may reflect “reverse causation” — suggesting that the timing of puberty itself might influence dietary choices, rather than the reverse.

Diet was assessed close to the time of menarche for many of the girls,” Roger told Euronews Health. “We know that diet quality can decline during adolescence, so the association may not be entirely one-way.”

Nonetheless, researchers agree that ensuring children have access to nutritious foods — particularly during the crucial developmental window around puberty — is vital. Harris emphasized the importance of school meal programmes grounded in evidence-based nutrition.

This research reinforces the need for equitable access to healthy meals for all children and adolescents, especially through school-based initiatives,” she said.

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Europe Pays Less for Medicines Than the U.S., but Prices Still Vary Widely by Country

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As former U.S. President Donald Trump reignites debate over America’s high drug prices, attention is once again turning to how Europe manages to pay far less for the same medicines—even if pricing remains inconsistent across the continent.

Trump, speaking to journalists on Monday, criticized the European Union for what he called “brutal” and “nasty” tactics in negotiating with pharmaceutical companies. He announced a proposal to link U.S. drug prices to the lowest rates paid by other wealthy nations, declaring: “We’re going to pay what Europe pays.”

According to a RAND Corporation analysis, the U.S. spent $617.2 billion (€542.7 billion) on pharmaceuticals in 2022—nearly three times the €205.3 billion spent by 24 European countries combined.

While it’s true that Europeans generally pay less, the picture within the region is far from uniform. A report by the World Health Organization (WHO) found that drug prices vary widely across Europe, largely due to confidential negotiations with drugmakers, national budget constraints, and differing approaches to price regulation.

In Switzerland, per capita spending on medicines reached €525, whereas Croatia spent just €262. These discrepancies reflect not only national income levels but also the complex and opaque nature of price-setting in the region. “There’s essentially no transparency,” said Huseyin Naci, an associate professor of health policy at the London School of Economics.

Many European countries base their pricing on what other nations pay and use cost-effectiveness assessments to determine value. England and Sweden emphasize whether a drug justifies its cost, while Germany looks at how much additional benefit it offers over existing treatments.

Still, costs have risen across the continent. In Germany, for instance, hospital drug prices increased 11.5% from 2012 to 2022, while retail pharmacy prices rose 2.6% in the same period. Health insurers have warned that rising prices are putting pressure on public health budgets.

If U.S. policy changes or drug companies push European nations to raise their prices, it would be highly disruptive,” Naci said.

European nations also differ in how drug costs are shared between public systems and individuals. In Cyprus, 90% of medicine expenses were covered by government or mandatory schemes in 2022. In Bulgaria, that figure was only 23%. Meanwhile, patients in some countries still pay out-of-pocket or through co-payments, depending on the condition being treated.

Despite lower overall spending, experts caution that European healthcare systems are already stretched thin. “There’s not much room left to absorb higher pharmaceutical costs,” Naci said.

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