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GSK Shares Surge Following $2.2 Billion Zantac Settlement

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Shares in pharmaceutical giant GlaxoSmithKline (GSK) surged by more than 6% after the company announced a settlement of up to $2.2 billion (€2.01 billion) to resolve tens of thousands of lawsuits in the US related to its discontinued heartburn medication, Zantac. The drug, once a blockbuster, had faced multiple allegations of causing cancer.

The settlement covers approximately 93% of the claims GSK was facing, which involves around 80,000 plaintiffs. An additional $70 million (€64 million) will be paid to resolve a whistleblower lawsuit brought by the US independent laboratory Valisure, which accused GSK of committing fraud by hiding the potential cancer risks associated with Zantac.

The whistleblower settlement is a “Qui Tam” case under the Financial Conduct Authority (FCA), a type of lawsuit where whistleblowers can file on behalf of the US government. Valisure’s claims played a significant role in the controversy surrounding the drug.

Zantac’s History and Concerns

Zantac, first introduced in the US in 1983, quickly became one of the world’s best-selling drugs, generating more than $1 billion (€0.91 billion) in annual sales. It was marketed by several major pharmaceutical companies, including Sanofi, Pfizer, and Boehringer Ingelheim.

However, concerns about the drug’s safety began to emerge in recent years. The key ingredient in Zantac, ranitidine, was found to potentially convert into a carcinogen, N-nitrosodimethylamine (NDMA), when stored at higher temperatures or over long periods. This prompted a series of recalls starting in 2019, with the US Food and Drug Administration (FDA) recalling the drug in 2020. Other countries, including the UK, Australia, and the European Union, also issued recalls.

Despite the legal settlement, GSK has continued to deny any wrongdoing, maintaining that the evidence linking ranitidine to cancer is inconsistent and unreliable.

GSK’s Statement on the Settlement

In a statement, GSK said: “While the scientific consensus remains that there is no consistent or reliable evidence that ranitidine increases the risk of any cancer, GSK strongly believes that these settlements are in the best long-term interests of the company and its shareholders as they remove significant financial uncertainty, risk, and distraction associated with protracted litigation.”

The company expects to record a charge of £1.8 billion (€2.15 billion) in its third-quarter results for 2024 in connection with the settlements. Despite the financial impact, GSK assured that these costs would not affect its growth agenda or research and development investment plans.

GSK’s stock rally reflects investor confidence that the settlement will bring resolution to the long-standing litigation and remove a significant overhang for the company.

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UniCredit Launches €10.1bn Bid for Banco BPM Amid Rising European Bank Mergers

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Italian banking giant UniCredit announced on Monday a surprise €10.1 billion all-stock offer to acquire its smaller rival, Banco BPM. The deal, which would merge two of Italy’s largest lenders, comes as UniCredit continues to increase its stake in Germany’s Commerzbank, signaling a significant push for growth and consolidation in Europe’s banking sector.

Under the terms of the offer, UniCredit is proposing 0.175 of its shares for each Banco BPM share, valuing the stock at €6.657 per share. This represents a modest premium of 0.5% over Banco BPM’s closing price on Friday.

In a statement, UniCredit emphasized the strategic importance of the proposed acquisition, stating that it aims to “strengthen the bank’s competitive position in Italy, one of the Group’s core markets … generating significant long-term value for all stakeholders and for Italy.” The lender also highlighted the potential for the merger to bolster its standing as a leading pan-European bank.

If successful, the deal would create Europe’s third-largest lender by market capitalization, marking a significant milestone for UniCredit.

No Impact on Commerzbank Investment

UniCredit CEO Andrea Orcel, who has been at the helm since 2021, clarified that the proposed takeover of Banco BPM would not affect the bank’s ongoing investment in Commerzbank.

UniCredit’s growing stake in the German lender has faced resistance in Berlin, where fears of job cuts and reduced support for small and medium-sized enterprises have sparked controversy. German Chancellor Olaf Scholz notably criticized potential hostile takeovers in late September, stating that “unfriendly attacks, hostile takeovers are not a good thing for banks.”

Banco BPM’s Recent Moves and European Merger Trends

The announcement follows a series of strategic actions by Banco BPM, including its recent purchase of a 5% stake in Monte dei Paschi di Siena (MPS), which many analysts see as a precursor to a potential merger. MPS, partially privatized after a 2017 bailout, has been reducing its state ownership, with the government’s stake now at around 11%.

Banco BPM has also launched a €1.6 billion offer for asset manager Anima Holding, seeking to diversify its revenue streams amid declining interest rates.

The proposed UniCredit-Banco BPM merger reflects a broader trend of consolidation in Europe’s banking sector, as lenders aim to enhance their scale and competitiveness against global rivals.

Banco BPM has not yet responded to requests for comment on the offer.

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Lithuania Emerges as a Leading Fintech and Startup Hub in Europe

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Lithuania is rapidly positioning itself as one of Europe’s top hubs for startups and financial technology (fintech), boasting a thriving ecosystem that has attracted global attention. Home to unicorns like Vinted and Nord Security, the Baltic nation is also nurturing a range of promising “soonicorns” poised to join the billion-dollar club.

A Rising Star in the Baltics

With a population of just 2.8 million, Lithuania is small compared to larger European nations. Yet, its startup ecosystem is thriving, outperforming its regional counterparts. According to the Lithuanian Startup Ecosystem 2023 report, the country’s startups were the fastest-growing in the Baltics last year. Between 2018 and 2023, Lithuania’s startup enterprise value surged 7.1 times, significantly outpacing the Baltic average of 2.7x and the 3.6x growth in Central and Eastern Europe (CEE).

Lithuania also ranked second in the CEE region for venture capital funding in 2023, securing €292 million. Notable soonicorns like Argyle, CityBee, and PVcase, valued between €200 million and €1 billion, highlight the country’s upward trajectory. Smaller but rapidly growing startups such as Affise, Whatagraph, and BitDegree are also making their mark.

The capital city, Vilnius, is a fintech hotspot, hosting over 170 startups valued at approximately €1.8 billion in 2023. In just 18 months leading up to February 2024, these companies raised €228 million in venture capital. Prominent names include Amlyze, Kevin, TransferGo, and HeavyFinance, which span industries such as payments, regulatory technology, and cryptocurrency.

Why Lithuania?

Employee well-being: Lithuania’s emphasis on work-life balance, mental health, and a vibrant work environment has made it particularly appealing to younger workers who dominate fintech sectors. The country recently topped the 2024 World Happiness Report for people under 30. Modern office designs and collaborative setups further enhance employee engagement.

Government initiatives: Organizations like Startup Lithuania, Invest Lithuania, and Vilnius Techfusion provide startups with invaluable support through acceleration programs, workshops, consultations, and relocation assistance. These initiatives connect startups with founders, investors, and tech specialists, fostering a collaborative ecosystem.

Ease of business: Ranked fifth globally for tax competitiveness and eighth for remote work, Lithuania offers an investor-friendly environment. Vilnius, known for its high-speed internet and robust online security, was named the most business-friendly city in Emerging Europe, making it a prime choice for tech-driven companies.

Lithuania’s strategic policies, talent pool, and tech-friendly infrastructure are solidifying its reputation as a fintech powerhouse, drawing investors and startups to its dynamic and rapidly growing ecosystem.

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Europe Faces Rising Gas Prices, Uncertainty Ahead of Winter Energy Demands

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Europe’s energy markets are bracing for a challenging winter as natural gas prices surge, driven by increased demand and supply uncertainties. The Dutch Title Transfer Facility (TTF), Europe’s benchmark for natural gas prices, recently hit a one-year high, reflecting growing concerns over supply shortfalls and geopolitical tensions.

Storage Levels Strong but Under Pressure

Despite early preparations, Europe’s gas storage reserves are facing significant withdrawals due to colder-than-expected weather. Data from Gas Infrastructure Europe shows that the first two weeks of November saw storage levels drop by nearly 4% (4.29 bcm). Current reserves remain robust at 95% capacity, surpassing the EU’s targets, but experts warn of depletion risks.

Dr. Yousef Alshammari, President of the London College of Energy Economics, noted that Europe’s gas reserves may fall below 50% by spring 2025, compared to 60% at the end of the previous winter. “Colder weather and increased heating demand will likely keep prices elevated compared to last year’s relatively mild winter,” Alshammari told Euronews Business.

Geopolitical Tensions and Supply Risks

The geopolitical landscape continues to weigh heavily on energy markets. Gazprom’s recent suspension of natural gas supplies to Austria over a bilateral dispute, coupled with the imminent expiration of a Russia-Ukraine gas transit agreement in January 2025, has heightened concerns about supply disruptions.

The end of the pipeline agreement could remove half of Russia’s remaining gas exports to Europe, exacerbating supply challenges during peak demand. “Any further disruption could force Europe to revert to coal and oil for power generation, which would have broader implications for energy markets,” said Alshammari.

Alshammari also highlighted that political dynamics, particularly the transition to a new U.S. administration, may influence energy prices. He cautioned that further tensions could amplify price volatility for both natural gas and oil.

Renewables and Energy Efficiency Mitigate Some Pressure

Renewable energy’s share of Europe’s electricity production reached 44.7% in 2024, up 12.4% from 2022, according to the Institute for Energy Economics and Financial Analysis. Improved energy efficiency and diversification have also helped mitigate demand for natural gas, which fell from 350 bcm in 2022 to 295 bcm in 2024.

However, Alshammari cautioned that renewables alone cannot resolve Europe’s energy challenges. “Countries with strong hydropower capabilities, like Norway and Iceland, are better positioned to avoid price spikes, but a diversified mix, including nuclear energy, is essential,” he said.

With increased reliance on LNG imports and the potential for heightened demand, Europe faces a delicate balancing act to maintain energy security while transitioning to a more sustainable energy future.

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