Health
Global Measles Cases Surge Amid Vaccine Coverage Challenges, WHO and CDC Report
A joint report by the World Health Organization (WHO) and the U.S. Centers for Disease Control and Prevention (CDC) has revealed a significant increase in global measles cases, with figures rising 20% to 10.3 million in 2023 compared to the previous year. The report highlights growing concerns about stalled immunization efforts worldwide.
In Europe, measles cases surged by over 200%, with more than 306,000 cases recorded in 2023, up from approximately 99,700 in 2022. This sharp rise has been attributed to gaps in vaccination coverage and an increase in localized outbreaks, according to WHO officials.
Declining Vaccination Coverage
The report underscores that global measles vaccination coverage remains below the necessary threshold to prevent outbreaks. While 83% of children worldwide received the first dose of the measles vaccine in 2023, only 73% received the second dose—far short of the 95% coverage required for effective herd immunity.
“The surge in cases is being driven by stalled global immunization coverage,” said Dr. Natasha Crowcroft, senior technical advisor for measles and rubella at WHO, during a press conference. “Every single country in the world has access to the measles vaccine, so there’s no reason why any child should be infected or die from this disease.”
Since 2000, vaccination efforts have prevented an estimated 60.3 million measles deaths. However, the report indicates that 22 million children missed their first dose in 2023, predominantly in low-income countries and conflict-affected areas where the risk of mortality from measles is highest.
Regional Variations
While Europe saw a dramatic rise in cases, the region still reported fewer overall cases compared to other parts of the world. According to a separate report by the European Centre for Disease Prevention and Control (ECDC), 18,000 measles cases were reported in European Union and European Economic Area countries between September 2023 and August 2024. Romania accounted for the majority, with over 14,000 cases.
Globally, Africa reported the highest number of cases, with an estimated 4.8 million in 2023, accounting for nearly half of all large outbreaks. Southeast Asia followed with 2.9 million cases.
Urgent Call for Action
Health officials are urging renewed efforts to address the immunization gap. “Vaccination is a proven, life-saving intervention, and no child should have to endure the devastating effects of measles,” Dr. Crowcroft emphasized.
The report’s findings serve as a stark reminder of the importance of maintaining robust immunization programs to protect children and communities worldwide from preventable diseases.
Health
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Health
Obesity Linked to Poorer Outcomes in Childhood Cancer Patients, Study Finds
Children with obesity diagnosed with cancer face significantly worse health outcomes, including a heightened risk of relapse and death, according to a new Canadian study.
The research, published in the journal Cancer, analyzed data from over 11,000 cancer patients aged 2 to 19, of whom 10.5% were obese at diagnosis. The study examined various cancers, including leukemia, lymphoma, and other tumors, and found that obesity negatively impacted outcomes across the entire cohort.
Increased Risk of Relapse and Mortality
The findings revealed that obese children had a 16% higher risk of cancer relapse and a 29% increased risk of death within five years of diagnosis, even after accounting for factors such as age, sex, and ethnicity.
“Our study highlights the negative impact of obesity among all types of childhood cancers,” said Dr. Thai Hoa Tran, a pediatric hematologist and oncologist at the University Hospital Centre Sainte-Justine in Montreal, Canada, and one of the study’s authors.
Dr. Tran emphasized the need for strategies to address obesity’s impact on cancer outcomes in future clinical trials and highlighted the importance of combating the childhood obesity epidemic to prevent severe health consequences.
Acute Lymphoblastic Leukemia and Brain Tumors Most Affected
The study found the impact of obesity was particularly pronounced in children with acute lymphoblastic leukemia (ALL)—a cancer of the blood and bone marrow—and brain tumors. Researchers suggested that fat tissue may play an active role in tumor progression, metastasis, and resistance to treatment.
Previous research has indicated that adipose (fat) tissue cells can promote tumor development and hinder the effectiveness of therapies. Additionally, the study noted concerns about potential undertreatment and inappropriate dosing of chemotherapy in obese patients, which could further compromise outcomes.
Limitations and Calls for Improved Measures
The researchers acknowledged limitations in their study, including reliance on body mass index (BMI) to define obesity. They pointed out that BMI is an imprecise measure that does not fully capture body composition or nutritional status.
“BMI remains a crude and imperfect measure,” the authors wrote, echoing recent calls from experts to adopt more accurate diagnostic tools for obesity. Critics argue that BMI may lead to overdiagnosis or fail to reflect the nuanced impact of weight on health outcomes.
Implications and Urgency
The findings underscore the urgent need for interventions targeting childhood obesity and call for more precise research to better understand the interplay between obesity and cancer treatment. As childhood obesity rates continue to rise globally, addressing this epidemic could have far-reaching implications for improving survival rates and health outcomes for young cancer patients.
Health
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