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Five Years On: COVID-19 Pandemic Leaves Lingering Mysteries and Challenges

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More than five years after the first cluster of COVID-19 cases emerged in Wuhan, China, the virus continues to evolve, leaving behind unanswered questions and a legacy of global disruption. The pandemic reshaped public health policies, exposed systemic inequities, and brought groundbreaking advances in vaccine development.

Origins of the Virus Remain Unclear

The origins of SARS-CoV-2, the virus causing COVID-19, remain uncertain. While scientists believe it likely originated in bats and was transmitted to humans through an intermediary species such as raccoon dogs or civet cats, this theory remains unproven. Speculation about a potential laboratory leak in Wuhan has further fueled political tensions.

The World Health Organization (WHO) recently urged China to share more data, calling transparency a “moral and scientific imperative” to help prevent future pandemics. However, experts caution that the true origin may never be definitively established.

Global Death Toll and Vaccination Efforts

The pandemic’s death toll remains staggering. While the WHO reports over seven million deaths worldwide, the actual number is estimated to exceed 20 million. Vulnerable populations, especially older adults, continue to account for a significant proportion of fatalities.

Despite these losses, the rapid development of COVID-19 vaccines has saved tens of millions of lives. The introduction of mRNA vaccines by Pfizer and Moderna in less than a year marked a scientific milestone, with more than 13 billion doses administered globally since 2021.

Vaccines have proven effective in reducing severe illness, hospitalizations, and deaths, though their protection against mild infections wanes over time. Researchers are working on next-generation vaccines, including nasal options, to better prevent infections.

Variants and Virus Evolution

The virus has continually mutated, with the omicron variant and its subvariants dominating since late 2021. Currently, KP.3 and a hybrid strain, XEC, are the primary variants in Europe. While these variants remain highly transmissible, existing vaccines and treatments have shown efficacy against them.

Long COVID: A Lingering Concern

Millions globally continue to grapple with long COVID, a condition characterized by persistent symptoms such as fatigue, brain fog, and cardiovascular issues. While vaccination reduces the risk, the root cause of long COVID remains unclear, complicating efforts to develop effective treatments.

Emerging research suggests remnants of the virus may linger in some patients’ bodies, offering clues but no definitive answers.

Looking Ahead

As humanity adjusts to a world where COVID-19 is no longer a leading cause of death but still a public health concern, the focus remains on monitoring variants, improving treatments, and addressing the long-term effects of the virus.

“The virus is still with us,” said WHO Director-General Tedros Adhanom Ghebreyesus. “We cannot talk about COVID in the past.”

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Climate Change Poses Growing Threat to Blood Supply and Demand, Australian Study Warns

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Climate change is poised to significantly disrupt both the supply and demand of blood for transfusions, according to a new study conducted by researchers from Red Cross Lifeblood and the University of the Sunshine Coast (UniSC). Published in The Lancet Planetary Health, the study outlines how increasing temperatures, extreme weather events, and the spread of infectious diseases could upend the current blood donation system.

The research highlights a dual threat: a shrinking pool of eligible blood donors due to health impacts and climate-induced disruptions, coupled with a rising demand for blood in disaster and disease-stricken areas.

“Climate change may impact some infectious diseases that can be transmitted via blood and can prevent people from donating,” said Dr. Elvina Viennet, one of the study’s co-authors. She emphasized that blood-borne illnesses such as Dengue Fever, West Nile Virus, and Malaria—driven by rising temperatures and increased rainfall—are becoming more prevalent in regions like Europe, affecting donor eligibility.

Currently, an estimated 25 million blood units are transfused each year across Europe. Blood is essential for a wide range of medical treatments, including surgeries, trauma care, managing chronic conditions, and supporting premature infants. However, disruptions in donor availability or blood storage due to climate extremes could pose serious risks.

“Extreme weather events can limit the mobility of people, disrupt transportation networks, and compromise blood storage conditions,” Viennet added. “This is particularly concerning because blood has a short shelf life and requires carefully regulated conditions.”

Helen Faddy, associate professor at UniSC and the study’s lead author, noted that climate-related health issues may further limit the pool of potential donors. “We could see new diseases emerge, and other health challenges such as blood pressure changes, dehydration from heatwaves, and psychological distress linked to climate anxiety that may affect individuals’ ability to donate,” she said.

Moreover, the study warns that the need for blood transfusions could also increase. Factors such as pregnancy complications, cardiovascular disease, and the rising incidence of sickle cell disease—conditions potentially exacerbated by climate change—may drive higher demand.

To mitigate these risks, the researchers propose several strategies, including the development of flexible and mobile blood collection centers, the use of cell salvage or autotransfusion techniques, and enhanced international collaboration to ensure a resilient and diverse blood supply.

“With rising sea levels and climate-related displacement likely to increase global migration, it’s vital to boost blood donation from a wider range of ethnic backgrounds,” Faddy stressed. “Encouraging more people to donate blood is a public health priority as climate impacts grow.”

The study serves as a call to action for health authorities worldwide to adapt blood donation systems in the face of escalating environmental challenges.

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EU Sees Record Surge in Harmful Consumer Products in 2024, Chemicals at Core of Concerns

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A record number of potentially dangerous consumer products were flagged across the European Union in 2024, with toxic chemicals emerging as a significant concern, according to a new report by the European Commission.

The findings, released through the EU’s Safety Gate Rapid Alert System, recorded over 4,100 alerts last year — the highest number reported in two decades. The system, which tracks threats in consumer and professional goods, excludes food and pharmaceuticals but covers a wide range of products, from cosmetics and clothing to toys and electronics.

The report identified several hazardous substances, including banned fragrances, heavy metals, and so-called “forever chemicals” that remain in the environment and the human body for extended periods. These substances pose serious health risks ranging from skin irritation and reproductive damage to long-term cognitive effects in children.

Banned Fragrance in Cosmetics

One of the most commonly detected substances was a synthetic fragrance known as 2-(4-tert-butylbenzyl) propionaldehyde (BMHCA), also listed as butylphenyl methylpropional. This chemical, which emits a floral scent similar to lily of the valley, was found in nearly all cosmetics reported for chemical risk.

BMHCA has been banned in EU cosmetics since March 2022 due to evidence linking it to skin irritation, fertility issues, and potential harm to unborn children. Despite the ban, it continues to appear in perfumes, deodorants, lotions, and hair products, raising concerns about enforcement and product safety.

Dangerous ‘Forever Chemicals’

The report also highlighted the presence of short-chain chlorinated paraffins (SCCPs) in items like cables and rubber-based products. SCCPs fall under the category of PFAS—per- and polyfluoroalkyl substances—often dubbed “forever chemicals” due to their extreme resistance to environmental breakdown.

Although the import and use of SCCPs are heavily regulated in the EU, these substances were still detected in several products. Research indicates that SCCPs can damage the liver and kidneys, disrupt hormones, and affect child development. The report also warned of their toxicity to aquatic life and potential to accumulate in the food chain.

Lead Exposure Remains a Risk

Another alarming discovery was the toxic metal lead in solders used for bonding metal parts. Even minimal exposure to lead is considered unsafe, with the World Health Organization noting that it can damage the brain, kidneys, and cardiovascular system. Lead is particularly harmful to children and pregnant women, with links to developmental delays, reduced IQ, and behavioral disorders such as ADHD.

An estimated 2.5 million children and adolescents in Western Europe have blood lead levels at or above five micrograms per decilitre — a threshold associated with multiple health issues.

Growing Health and Environmental Concerns

The European Commission’s report underscores the need for stricter enforcement of safety regulations and increased consumer awareness. It also calls on manufacturers and importers to prioritize non-toxic materials and improve product traceability to ensure compliance with EU safety standards.

As concerns about chemical exposure and environmental toxicity grow, the report highlights the urgent need for coordinated efforts to protect public health and the environment from harmful consumer products.

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Experts Warn Against Viral TikTok Weight Loss Trends

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Misleading weight loss trends are taking social media by storm, with millions of TikTok users sharing and trying out DIY hacks that promise rapid results without leaving home. However, health experts are raising concerns about their effectiveness and potential harm.

Among the most popular weight loss fads currently trending on TikTok are the castor oil belly rub and the coffee with lemon drink. These viral methods have racked up tens of thousands of likes and views, but health professionals caution that their benefits are overstated—and in some cases, entirely fictional.

The castor oil trend involves rubbing the oil, derived from castor beans, onto the stomach with claims that it can flatten the belly within weeks. A single TikTok post promoting this method has garnered over 49,000 likes.

However, Priya Tew, a specialist dietitian and spokesperson for the British Dietetic Association, dismissed the claims. “There is no proof that applying castor oil can affect your internal fat or aid in weight loss,” she said. “It’s essentially just moisturizing your skin.”

Dr. Adam Collins, Professor of Nutrition at the University of Surrey, agreed. “There’s no metabolic reason for castor oil to impact visceral fat. These claims are simply not based on science.”

Another enduring trend is adding lemon to coffee, which surged in popularity in 2024 and remains widely shared in 2025. Supporters suggest the mixture boosts metabolism and fat burning due to caffeine’s natural stimulant effects.

But experts say that while caffeine can slightly increase metabolism, the impact is minimal. “It’s not like you’ll suddenly burn hundreds more calories,” said Dr. Collins. “And high doses of caffeine can lead to other health issues.”

Dr. Christophe Matthys, professor of Human Nutrition at KU Leuven, warned of additional risks. “Overconsumption of caffeine can affect sleep and disrupt hunger cues, leading to overeating,” he explained. “That can actually work against weight loss goals.”

Beyond physical health, experts are also worried about the psychological toll these trends may have, especially on younger audiences. “People can develop distorted relationships with food,” said Matthys. “These ideas often aren’t based on any scientific understanding but can leave lasting mental effects.”

Tew emphasized that sustainable weight loss comes from consistent, manageable changes—not viral shortcuts. “Adding a portion of fruit, snacking on nuts instead of crisps—these are the kinds of small changes that make a long-term difference,” she said.

Importantly, she also stressed that weight isn’t the only—or best—indicator of health. “We can be healthy in all shapes and sizes. Being in a larger body doesn’t necessarily mean you’re unhealthy or need to lose weight,” she added.

As TikTok continues to shape wellness conversations, experts urge users to be critical of trends and to seek evidence-based advice when it comes to their health.

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