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Experts Explore Link Between Maternal Infections and Autism Risk

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The relationship between maternal infections during pregnancy and the increased likelihood of autism in children has been a topic of growing research interest. While autism spectrum disorder (ASD) is not classified as an illness or disease but rather a range of traits with varying severity, scientists continue to examine factors that may influence its development.

Investigating Maternal Infections

One area of focus is the potential role of infections such as influenza during pregnancy. Research suggests that such infections may contribute to a higher risk of autism, though they are not considered direct causes. “Our work suggests that women with febrile episodes, high antibody levels to certain viruses like herpes simplex type 2, or confirmed influenza cases are at greater risk of having children diagnosed with ASD,” explained Dr. Ian Lipkin, director of Columbia University’s Center for Infection and Immunity, in an interview with Euronews Health.

Lipkin’s study emphasized laboratory-confirmed flu cases and found evidence of increased ASD risk when severe flu symptoms were reported. He noted that maternal immune responses, rather than the virus itself, might be the key factor, as inflammation could disrupt normal fetal development.

Understanding the Role of Inflammation

To explore this further, researchers have turned to animal models. Dr. Irene Sanchez Martin, a postdoctoral researcher at Cold Spring Harbor Laboratory, presented findings from her study on how maternal immune activation (MIA) in mice correlates with neurodevelopmental disorders resembling autism in humans.

Her research simulated viral infections during pregnancy, equivalent to the first trimester in humans, and observed early developmental deficits in embryos, particularly in males. “We cannot say that a mouse has autism,” Sanchez Martin clarified, “but they can exhibit behavioral abnormalities associated with neurodevelopmental disorders, including autism.”

The study highlighted disruptions in the fetal environment, such as changes to the amniotic fluid and placenta, as potential contributors to developmental issues.

Focus on Inflammation, Not the Virus

Both Lipkin and Sanchez Martin emphasized the role of inflammation over the specific infectious agent. Elevated levels of cytokines, markers of inflammation, were commonly observed in mothers of children diagnosed with autism. “It’s the inflammation that is associated with these problems, not the infectious agent itself,” Sanchez Martin stated.

While animal studies cannot fully replicate human conditions, they provide insights into how maternal immune responses might influence fetal development. These findings underscore the need for further research into the complex interactions between genetic, environmental, and immunological factors in autism.

Understanding these connections could lead to preventive measures and improved maternal health strategies, offering hope for reducing the impact of such risks on child development.

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Europe Faces Growing Challenges in Meeting Medical Care Needs, EU Report Shows

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A new report has highlighted stark disparities in healthcare access across Europe, revealing that a growing number of citizens face unmet medical needs due to systemic issues such as high costs and long waiting times.

According to the latest data from Eurostat and the Health at a Glance: Europe 2024 report, 3.8 per cent of EU residents aged 16 and over reported unmet medical needs in the past year. However, the percentage climbs significantly when focusing solely on individuals who actively required healthcare services — with some countries reporting unmet needs among over 20 per cent of this group.

The causes are twofold: healthcare system barriers, including long waiting lists and treatment costs, account for 2.4 per cent of all cases, while 1.4 per cent stem from personal reasons such as fear of doctors, lack of time, or lack of knowledge about available care.

Unmet healthcare needs vary widely across the continent. Estonia tops the list within the EU, with 15.5 per cent of people reporting unmet needs, followed closely by Greece and Albania, each over 13 per cent. Even wealthier Nordic countries show surprising figures — Denmark (12.2 per cent), Finland, and Norway (over 7.5 per cent) — despite high healthcare spending. Conversely, countries such as Germany (0.5 per cent), Austria (1.3 per cent), and the Netherlands (1.4 per cent) report the lowest levels, pointing to more efficient and accessible healthcare systems.

Cost is a dominant barrier in nations like Greece and Albania, where over 9 per cent of citizens cited unaffordable care. In contrast, long waiting times are the primary issue in countries like Estonia (12 per cent) and Finland (7.5 per cent).

Income inequality also plays a major role. On average, 3.8 per cent of low-income individuals across the EU report unmet needs due to healthcare system issues — more than triple the 1.2 per cent reported by higher-income groups. In Greece, that gap is particularly wide, with 23 per cent of low-income respondents affected.

Healthcare experts say these disparities reflect more than just economic factors. Dr. Tit Albreht, President of the European Public Health Association (EUPHA), noted, “Unmet health needs arise from different reasons, including how well healthcare governance integrates services to meet population needs.”

Industry leaders, such as Tina Taube of the European Federation of Pharmaceutical Industries and Associations (EFPIA), stressed the importance of timely access to diagnosis and treatment. “Unmet needs are context-specific,” she said. “It’s not just about product availability, but also healthcare system readiness.”

Andy Powrie-Smith of EFPIA added that patients in some European countries wait up to seven times longer than others for the same treatments due to regulatory delays and varying national infrastructures.

The findings underscore the need for a more coordinated, equitable healthcare strategy across the continent, especially as Europe faces the challenges of an ageing population and increasingly complex medical technologies.

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Chinese Nationals Charged in U.S. with Smuggling Toxic Fungus Labeled a Potential Agroterrorism Threat

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U.S. federal authorities have charged two Chinese nationals in connection with smuggling a dangerous agricultural fungus into the country, a move investigators describe as posing significant national security risks.

Yunqing Jian, 33, and Zunyong Liu, 34, are accused of conspiracy, smuggling, making false statements, and visa fraud after allegedly attempting to bring Fusarium graminearum — a toxic fungus capable of devastating crops and harming humans and livestock — into the United States. The case was detailed in a court filing by the Federal Bureau of Investigation (FBI) in Detroit.

The fungus, which targets essential food staples like wheat, maize, barley, and rice, is described in a scientific journal cited by the FBI as a “potential agroterrorism weapon.” Experts warn that its spread could inflict serious damage on global food security and agricultural economies.

U.S. Attorney Jerome Gorgon Jr. emphasized the seriousness of the case, stating: “The alleged actions of these Chinese nationals, including a loyal member of the Chinese Communist Party, are of the gravest national security concerns.”

Jian made her first appearance in a Detroit federal court on Tuesday and remains in custody awaiting a bond hearing scheduled for Thursday. A court-appointed attorney for her initial appearance declined to comment.

According to the FBI’s complaint, the investigation began in July 2024 when Liu was stopped at Detroit Metropolitan Airport. During a routine screening, customs officials discovered suspicious red plant material in his backpack. Liu initially claimed not to know what it was but later admitted he planned to use it for research purposes at the University of Michigan, where Jian is currently employed and where Liu previously worked.

Authorities say Liu’s mobile phone contained an article titled “Plant-Pathogen Warfare under Changing Climate Conditions,” raising further concerns about the intended use of the samples. The FBI believes the two individuals were coordinating to introduce the pathogen into a U.S. research setting without proper clearance or oversight.

Liu was denied entry to the U.S. and deported in July. Charges against both individuals were filed this week, as prosecutors continue to investigate the scope of the alleged conspiracy.

The case underscores growing concerns in the U.S. over biosecurity and potential misuse of scientific research amid rising geopolitical tensions.

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US Expands Measles Vaccination Guidance Amid Global Surge in Cases

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U.S. health officials have expanded their vaccination guidance for international travellers as measles cases rise sharply around the world, including in Europe and the United States.

The Centers for Disease Control and Prevention (CDC) now recommends that all international travellers be vaccinated against measles, regardless of their destination. Previously, the CDC’s focus was on countries experiencing known outbreaks, but this latest update reflects growing concern over transmission during travel itself.

“This change is significant,” said Ashley Darcy-Mahoney, a health researcher at George Washington University’s School of Nursing. “We’re seeing a shift from localised outbreaks to transmission in transit. Measles is now being spread not only in outbreak zones but also on airplanes and during international travel.”

The updated guidance urges U.S. travellers aged 1 year and older to receive two doses of the measles-mumps-rubella (MMR) vaccine before departing the country. Infants between 6 and 11 months old should receive an early dose, aligning with recommendations from the European Centre for Disease Prevention and Control (ECDC), which has also advised travellers to ensure they are fully vaccinated.

Measles is a highly contagious viral disease that spreads through coughing, sneezing, and close contact. Even brief exposure in confined spaces—such as airports or airplanes—can result in infection, particularly among unvaccinated individuals.

The CDC’s change comes amid a troubling global resurgence of measles. So far in 2025, more than 1,000 measles cases have been reported across the U.S., while the European Union has logged over 5,500 cases. Health officials have attributed many of the new infections to gaps in immunisation, often exacerbated by misinformation and pandemic-related disruptions to routine childhood vaccinations.

In the U.S., a recent outbreak in Colorado was traced back to an international flight that landed in Denver, underscoring the risks of in-flight transmission and the importance of proactive immunisation.

Measles was declared eliminated in the U.S. in 2000, but periodic outbreaks have occurred in recent years, often linked to unvaccinated travellers bringing the virus back from abroad.

Public health experts stress that maintaining high vaccination coverage is key to preventing further spread. The MMR vaccine is safe and highly effective, providing lifelong protection in most individuals after two doses.

“Given the rise in global travel and measles cases, the updated CDC guidance is a timely reminder that vaccination remains one of our strongest tools to protect public health,” Darcy-Mahoney said.

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