Health
Experimental Alzheimer’s Drug Shows Promise in Reducing Dementia Risk
A new experimental treatment targeting amyloid plaques in the brain has shown promising early results in reducing the risk of Alzheimer’s-related dementia among asymptomatic patients. The drug, gantenerumab, was studied in a small group of individuals genetically predisposed to the neurodegenerative disease.
Researchers tracked 22 patients with genetic mutations that cause an overproduction of amyloid, a protein that clumps together to form plaques in the brain, a hallmark of Alzheimer’s disease. According to findings published in Lancet Neurology, participants who took gantenerumab for eight years saw their risk of developing symptoms drop from 100% to approximately 50%.
Long-Term Treatment May Be Key
The study’s lead author, Randall Bateman, a professor of neurology at Washington University School of Medicine in the U.S., emphasized the significance of the results. “Everyone in this study was destined to develop Alzheimer’s disease, and some of them haven’t yet,” Bateman said. “To give them the best opportunity to stay cognitively normal, we have continued treatment with another anti-amyloid antibody in hopes they will never develop symptoms at all.”
Notably, cognitive benefits were observed only in patients who received the treatment for the full eight years. Those who were treated for only two to three years did not show noticeable improvements, suggesting that long-term preventive therapy may be necessary for effectiveness.
Challenges and Limitations
Despite the encouraging results, experts have pointed out limitations in the study. Charles Marshall, a professor of clinical neurology at Queen Mary University of London, called the findings “very exciting” but noted that the study involved a small number of participants and was a secondary evaluation rather than a primary clinical trial.
Another concern is that gantenerumab is not as effective as some newer amyloid-reducing treatments, suggesting there may be even better options available. The drug was discontinued in 2022 after failing to slow symptoms in a trial involving over 1,900 participants with more common forms of Alzheimer’s disease.
Future Research Needed
While gantenerumab has shown potential in genetically predisposed individuals, further research is required to determine the optimal treatment duration, the effects on non-genetic cases of Alzheimer’s, and possible side effects. Some anti-amyloid drugs have been linked to brain abnormalities and localized swelling, though most side effects resolve on their own. In the study, two participants had to stop taking the drug due to side effects, but no life-threatening adverse effects were reported.
The findings contribute to the growing body of research on anti-amyloid therapies, highlighting the need for continued investigation into more effective Alzheimer’s prevention and treatment strategies.
Health
Climate Change Poses Growing Threat to Blood Supply and Demand, Australian Study Warns
Climate change is poised to significantly disrupt both the supply and demand of blood for transfusions, according to a new study conducted by researchers from Red Cross Lifeblood and the University of the Sunshine Coast (UniSC). Published in The Lancet Planetary Health, the study outlines how increasing temperatures, extreme weather events, and the spread of infectious diseases could upend the current blood donation system.
The research highlights a dual threat: a shrinking pool of eligible blood donors due to health impacts and climate-induced disruptions, coupled with a rising demand for blood in disaster and disease-stricken areas.
“Climate change may impact some infectious diseases that can be transmitted via blood and can prevent people from donating,” said Dr. Elvina Viennet, one of the study’s co-authors. She emphasized that blood-borne illnesses such as Dengue Fever, West Nile Virus, and Malaria—driven by rising temperatures and increased rainfall—are becoming more prevalent in regions like Europe, affecting donor eligibility.
Currently, an estimated 25 million blood units are transfused each year across Europe. Blood is essential for a wide range of medical treatments, including surgeries, trauma care, managing chronic conditions, and supporting premature infants. However, disruptions in donor availability or blood storage due to climate extremes could pose serious risks.
“Extreme weather events can limit the mobility of people, disrupt transportation networks, and compromise blood storage conditions,” Viennet added. “This is particularly concerning because blood has a short shelf life and requires carefully regulated conditions.”
Helen Faddy, associate professor at UniSC and the study’s lead author, noted that climate-related health issues may further limit the pool of potential donors. “We could see new diseases emerge, and other health challenges such as blood pressure changes, dehydration from heatwaves, and psychological distress linked to climate anxiety that may affect individuals’ ability to donate,” she said.
Moreover, the study warns that the need for blood transfusions could also increase. Factors such as pregnancy complications, cardiovascular disease, and the rising incidence of sickle cell disease—conditions potentially exacerbated by climate change—may drive higher demand.
To mitigate these risks, the researchers propose several strategies, including the development of flexible and mobile blood collection centers, the use of cell salvage or autotransfusion techniques, and enhanced international collaboration to ensure a resilient and diverse blood supply.
“With rising sea levels and climate-related displacement likely to increase global migration, it’s vital to boost blood donation from a wider range of ethnic backgrounds,” Faddy stressed. “Encouraging more people to donate blood is a public health priority as climate impacts grow.”
The study serves as a call to action for health authorities worldwide to adapt blood donation systems in the face of escalating environmental challenges.
Health
EU Sees Record Surge in Harmful Consumer Products in 2024, Chemicals at Core of Concerns
A record number of potentially dangerous consumer products were flagged across the European Union in 2024, with toxic chemicals emerging as a significant concern, according to a new report by the European Commission.
The findings, released through the EU’s Safety Gate Rapid Alert System, recorded over 4,100 alerts last year — the highest number reported in two decades. The system, which tracks threats in consumer and professional goods, excludes food and pharmaceuticals but covers a wide range of products, from cosmetics and clothing to toys and electronics.
The report identified several hazardous substances, including banned fragrances, heavy metals, and so-called “forever chemicals” that remain in the environment and the human body for extended periods. These substances pose serious health risks ranging from skin irritation and reproductive damage to long-term cognitive effects in children.
Banned Fragrance in Cosmetics
One of the most commonly detected substances was a synthetic fragrance known as 2-(4-tert-butylbenzyl) propionaldehyde (BMHCA), also listed as butylphenyl methylpropional. This chemical, which emits a floral scent similar to lily of the valley, was found in nearly all cosmetics reported for chemical risk.
BMHCA has been banned in EU cosmetics since March 2022 due to evidence linking it to skin irritation, fertility issues, and potential harm to unborn children. Despite the ban, it continues to appear in perfumes, deodorants, lotions, and hair products, raising concerns about enforcement and product safety.
Dangerous ‘Forever Chemicals’
The report also highlighted the presence of short-chain chlorinated paraffins (SCCPs) in items like cables and rubber-based products. SCCPs fall under the category of PFAS—per- and polyfluoroalkyl substances—often dubbed “forever chemicals” due to their extreme resistance to environmental breakdown.
Although the import and use of SCCPs are heavily regulated in the EU, these substances were still detected in several products. Research indicates that SCCPs can damage the liver and kidneys, disrupt hormones, and affect child development. The report also warned of their toxicity to aquatic life and potential to accumulate in the food chain.
Lead Exposure Remains a Risk
Another alarming discovery was the toxic metal lead in solders used for bonding metal parts. Even minimal exposure to lead is considered unsafe, with the World Health Organization noting that it can damage the brain, kidneys, and cardiovascular system. Lead is particularly harmful to children and pregnant women, with links to developmental delays, reduced IQ, and behavioral disorders such as ADHD.
An estimated 2.5 million children and adolescents in Western Europe have blood lead levels at or above five micrograms per decilitre — a threshold associated with multiple health issues.
Growing Health and Environmental Concerns
The European Commission’s report underscores the need for stricter enforcement of safety regulations and increased consumer awareness. It also calls on manufacturers and importers to prioritize non-toxic materials and improve product traceability to ensure compliance with EU safety standards.
As concerns about chemical exposure and environmental toxicity grow, the report highlights the urgent need for coordinated efforts to protect public health and the environment from harmful consumer products.
Health
Experts Warn Against Viral TikTok Weight Loss Trends
Misleading weight loss trends are taking social media by storm, with millions of TikTok users sharing and trying out DIY hacks that promise rapid results without leaving home. However, health experts are raising concerns about their effectiveness and potential harm.
Among the most popular weight loss fads currently trending on TikTok are the castor oil belly rub and the coffee with lemon drink. These viral methods have racked up tens of thousands of likes and views, but health professionals caution that their benefits are overstated—and in some cases, entirely fictional.
The castor oil trend involves rubbing the oil, derived from castor beans, onto the stomach with claims that it can flatten the belly within weeks. A single TikTok post promoting this method has garnered over 49,000 likes.
However, Priya Tew, a specialist dietitian and spokesperson for the British Dietetic Association, dismissed the claims. “There is no proof that applying castor oil can affect your internal fat or aid in weight loss,” she said. “It’s essentially just moisturizing your skin.”
Dr. Adam Collins, Professor of Nutrition at the University of Surrey, agreed. “There’s no metabolic reason for castor oil to impact visceral fat. These claims are simply not based on science.”
Another enduring trend is adding lemon to coffee, which surged in popularity in 2024 and remains widely shared in 2025. Supporters suggest the mixture boosts metabolism and fat burning due to caffeine’s natural stimulant effects.
But experts say that while caffeine can slightly increase metabolism, the impact is minimal. “It’s not like you’ll suddenly burn hundreds more calories,” said Dr. Collins. “And high doses of caffeine can lead to other health issues.”
Dr. Christophe Matthys, professor of Human Nutrition at KU Leuven, warned of additional risks. “Overconsumption of caffeine can affect sleep and disrupt hunger cues, leading to overeating,” he explained. “That can actually work against weight loss goals.”
Beyond physical health, experts are also worried about the psychological toll these trends may have, especially on younger audiences. “People can develop distorted relationships with food,” said Matthys. “These ideas often aren’t based on any scientific understanding but can leave lasting mental effects.”
Tew emphasized that sustainable weight loss comes from consistent, manageable changes—not viral shortcuts. “Adding a portion of fruit, snacking on nuts instead of crisps—these are the kinds of small changes that make a long-term difference,” she said.
Importantly, she also stressed that weight isn’t the only—or best—indicator of health. “We can be healthy in all shapes and sizes. Being in a larger body doesn’t necessarily mean you’re unhealthy or need to lose weight,” she added.
As TikTok continues to shape wellness conversations, experts urge users to be critical of trends and to seek evidence-based advice when it comes to their health.
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